Reducing cisplatin ototoxicity in children: some hope and many questions by Bouffet, Eric

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Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis by Thompson, Eric M, MD, Hielscher, Thomas, MSc, Bouffet, Eric, Prof, Remke, Marc, MD, Luu, Betty, BSc, Gururangan, Sridharan, Prof, McLendon, Roger E, Prof, Bigner, Darell D, Prof, Lipp, Eric S, MD, Perreault, Sebastien, MD, Cho, Yoon-Jae, MD, Grant, Gerald, MD, Kim, Seung-Ki, Prof, Lee, Ji Yeoun, MD, Rao, Amulya A Nageswara, MD, Li, Kay Ka Wai, MD, Ng, Ho-Keung, Prof, Yao, Yu, MD, Kumabe, Toshihiro, MD, Tominaga, Teiji, Prof, Grajkowska, Wieslawa A, Prof, Perek-Polnik, Marta, Prof, Low, David C Y, MBBCh, Seow, Wan Tew, MBBS, Chang, Kenneth T E, MBBCh, Mora, Jaume, Prof, Pollack, Ian F, Prof, Hamilton, Ronald L, MD, Leary, Sarah, MD, Moore, Andrew S, PhD, Ingram, Wendy J, PhD, Hallahan, Andrew R, MBBS, Jouvet, Anne, MD, Fèvre-Montange, Michelle, PhD, Vasiljevic, Alexandre, MD, Faure-Conter, Cecile, MD, Shofuda, Tomoko, PhD, Hashimoto, Naoya, MD, Jabado, Nada, MD, Weil, Alexander G, MD, Gayden, Tenzin, PhD, Wataya, Takafumi, MD, Shalaby, Tarek, MD, Grotzer, Michael, Prof, Zitterbart, Karel, PhD, Sterba, Jaroslav, Prof, Kren, Leos, MD, Hortobágyi, Tibor, Prof, Klekner, Almos, PhD, László, Bognár, Prof, Pócza, Tímea, MSc, Hauser, Peter, MD, Schüller, Ulrich, MD, Jung, Shin, Prof, Jang, Woo-Youl, MD, French, Pim J, Prof, Kros, Johan M, Prof, van Veelen, Marie-Lise C, MD, Massimi, Luca, MD, Leonard, Jeffrey R, Prof, Rubin, Joshua B, MD, Vibhakar, Rajeev, MD, Chambless, Lola B, MD, Cooper, Michael K, MD, Thompson, Reid C, Prof, Carvalho, Alice, MD, Nunes, Sofia, MD, Pimentel, José, MD, Fan, Xing, MD, Lyden, David, Prof, Garzia, Livia, PhD, Shih, David J H, PhD, Kijima, Noriyuki, MD, Schneider, Christian, MD, Adamski, Jennifer, PhD, Northcott, Paul A, PhD, Kool, Marcel, PhD, Jones, David T W, PhD, Chan, Jennifer A, MD, Nikolic, Ana, MD, Garre, Maria Luisa, MD, Van Meir, Erwin G, Prof, Osuka, Satoru, MD, Olson, Jeffrey J, Prof, Jahangiri, Arman, BSc, Castro, Brandyn A, BSc, Gupta, Nalin, MD, Moxon-Emre, Iska, MSc, Mabbott, Donald J, PhD, Lassaletta, Alvaro, MD, Hawkins, Cynthia E, Prof, Tabori, Uri, MD, Drake, James, Prof, Kulkarni, Abhaya, Prof, Dirks, Peter, Prof, Rutka, James T, Prof, Pfister, Stefan M, Prof, Packer, Roger J, Prof, Ramaswamy, Vijay, MD, Taylor, Michael D, Dr Prof

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Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas by Ryall, Scott, Zapotocky, Michal, Fukuoka, Kohei, Nobre, Liana, Guerreiro Stucklin, Ana, Bennett, Julie, Siddaway, Robert, Li, Christopher, Pajovic, Sanja, Arnoldo, Anthony, Kowalski, Paul E., Johnson, Monique, Sheth, Javal, Lassaletta, Alvaro, Tatevossian, Ruth G., Orisme, Wilda, Qaddoumi, Ibrahim, Surrey, Lea F., Li, Marilyn M., Waanders, Angela J., Gilheeney, Stephen, Rosenblum, Marc, Bale, Tejus, Tsang, Derek S., Laperriere, Normand, Kulkarni, Abhaya, Ibrahim, George M., Drake, James, Dirks, Peter, Taylor, Michael D., Rutka, James T., Laughlin, Suzanne, Shroff, Manohar, Shago, Mary, Hazrati, Lili-Naz, D'Arcy, Colleen, Ramaswamy, Vijay, Bartels, Ute, Huang, Annie, Bouffet, Eric, Karajannis, Matthias A., Santi, Mariarita, Ellison, David W., Tabori, Uri, Hawkins, Cynthia

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Diffuse brainstem glioma in children: critical review of clinical trials by Hargrave, Darren, Bartels, Ute, Bouffet, Eric

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A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway: TRAM-01 by Perreault, Sébastien, Larouche, Valérie, Tabori, Uri, Hawkin, Cynthia, Lippé, Sarah, Ellezam, Benjamin, Décarie, Jean-Claude, Théoret, Yves, Métras, Marie-Élaine, Sultan, Serge, Cantin, Édith, Routhier, Marie-Ève, Caru, Maxime, Legault, Geneviève, Bouffet, Éric, Lafay-Cousin, Lucie, Hukin, Juliette, Erker, Craig, Jabado, Nada

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Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas by Guerreiro Stucklin, Ana S., Ryall, Scott, Fukuoka, Kohei, Zapotocky, Michal, Lassaletta, Alvaro, Li, Christopher, Bridge, Taylor, Kim, Byungjin, Arnoldo, Anthony, Kowalski, Paul E., Zhong, Yvonne, Johnson, Monique, Li, Claire, Ramani, Arun K., Siddaway, Robert, Nobre, Liana Figueiredo, de Antonellis, Pasqualino, Dunham, Christopher, Cheng, Sylvia, Boué, Daniel R., Finlay, Jonathan L., Coven, Scott L., de Prada, Inmaculada, Perez-Somarriba, Marta, Faria, Claudia C., Grotzer, Michael A., Rushing, Elisabeth, Sumerauer, David, Zamecnik, Josef, Krskova, Lenka, Garcia Ariza, Miguel, Cruz, Ofelia, Morales La Madrid, Andres, Solano, Palma, Terashima, Keita, Nakano, Yoshiko, Ichimura, Koichi, Nagane, Motoo, Sakamoto, Hiroaki, Gil-da-Costa, Maria Joao, Silva, Roberto, Johnston, Donna L., Michaud, Jean, Wilson, Bev, van Landeghem, Frank K. H., Oviedo, Angelica, McNeely, P. Daniel, Crooks, Bruce, Fried, Iris, Zhukova, Nataliya, Hansford, Jordan R., Nageswararao, Amulya, Garzia, Livia, Shago, Mary, Brudno, Michael, Irwin, Meredith S., Bartels, Ute, Ramaswamy, Vijay, Bouffet, Eric, Taylor, Michael D., Tabori, Uri, Hawkins, Cynthia

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Risk stratification of childhood medulloblastoma in the molecular era: the current consensus by Ramaswamy, Vijay, Remke, Marc, Bouffet, Eric, Bailey, Simon, Clifford, Steven C., Doz, Francois, Kool, Marcel, Dufour, Christelle, Vassal, Gilles, Milde, Till, Witt, Olaf, von Hoff, Katja, Pietsch, Torsten, Northcott, Paul A., Gajjar, Amar, Robinson, Giles W., Padovani, Laetitia, André, Nicolas, Massimino, Maura, Pizer, Barry, Packer, Roger, Rutkowski, Stefan, Pfister, Stefan M., Taylor, Michael D., Pomeroy, Scott L.

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The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants by Pajtler, Kristian W., Mack, Stephen C., Ramaswamy, Vijay, Smith, Christian A., Witt, Hendrik, Smith, Amy, Hansford, Jordan R., von Hoff, Katja, Wright, Karen D., Hwang, Eugene, Frappaz, Didier, Kanemura, Yonehiro, Massimino, Maura, Faure-Conter, Cécile, Modena, Piergiorgio, Tabori, Uri, Warren, Katherine E., Holland, Eric C., Ichimura, Koichi, Giangaspero, Felice, Castel, David, von Deimling, Andreas, Kool, Marcel, Dirks, Peter B., Grundy, Richard G., Foreman, Nicholas K., Gajjar, Amar, Korshunov, Andrey, Finlay, Jonathan, Gilbertson, Richard J., Ellison, David W., Aldape, Kenneth D., Merchant, Thomas E., Bouffet, Eric, Pfister, Stefan M., Taylor, Michael D.

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EANO, SNO and Euracan consensus review on the current management and future development of intracranial germ cell tumors in adolescents and young adults by Frappaz, Didier, Dhall, Girish, Murray, Matthew J, Goldman, Stuart, Faure Conter, Cecile, Allen, Jeffrey, Kortmann, Rolf Dieter, Haas-Kogen, Daphne, Morana, Giovanni, Finlay, Jonathan, Nicholson, James C, Bartels, Ute, Souweidane, Mark, Schönberger, Stefan, Vasiljevic, Alexandre, Robertson, Patricia, Albanese, Assunta, Alapetite, Claire, Czech, Thomas, Lau, Chin C, Wen, Patrick, Schiff, David, Shaw, Dennis, Calaminus, Gabriele, Bouffet, Eric

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Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors by Hoffman, Lindsey M, Richardson, Elizabeth Anne, Ho, Ben, Margol, Ashley, Reddy, Alyssa, Lafay-Cousin, Lucie, Chi, Susan, Slavc, Irene, Judkins, Alexander, Hasselblatt, Martin, Bourdeaut, Franck, Frühwald, Michael C, Vibhakar, Rajeev, Bouffet, Eric, Huang, Annie

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Divergent clonal selection dominates medulloblastoma at recurrence by Garzia, Livia, Zuyderduyn, Scott, Huang, Xi, Skowron, Patryk, Remke, Marc, Cavalli, Florence M. G., Ramaswamy, Vijay, Lindsay, Patricia E., Jelveh, Salomeh, Donovan, Laura K., Wang, Xin, Luu, Betty, Zayne, Kory, Thiessen, Nina, Mercier, Eloi, Mungall, Karen L., Ma, Yusanne, Tse, Kane, Shumansky, Karey, Roth, Andrew J. L., Shah, Sohrab, Farooq, Hamza, Holgado, Borja L., Liu, Jessica, Mack, Stephen C., Nor, Carolina, Rolider, Adi, Thompson, Yuan Y., Wu, Xiaochong, Pugh, Trevor, Ally, Adrian, Bilenky, Mikhail, Cheng, Young, Corbett, Richard D., He, An, Li, Haiyan I., Long, William, Mayo, Michael, Plettner, Patrick, Qian, Jenny Q., Schein, Jacqueline E., Tam, Angela, Wong, Tina, Zhao, Yongjun, Pimentel, José, Shalaby, Tarek, Hamilton, Ronald L., Li, Xiao-Nan, Bendel, Anne E., Fults, Daniel W., Walter, Andrew W., Kumabe, Toshihiro, Tominaga, Teiji, Collins, V. Peter, Cho, Yoon-Jae, Hoffman, Caitlin, Garvin, James H., Stearns, Duncan S., Schüller, Ulrich, Zitterbart, Karel, Puget, Stephanie, Ayrault, Olivier, Dunn, Sandra E., Tirapelli, Daniela P. C., Hallahan, Andrew R., Ingram, Wendy, MacDonald, Tobey J., Olson, Jeffrey J., Van Meir, Erwin G., Lee, Ji-Yeoun, Wang, Kyu-Chang, Kim, Seung-Ki, Cho, Byung-Kyu, Pietsch, Torsten, Fleischhack, Gudrun, Tippelt, Stephan, Lindsey, Janet C., Clifford, Steven C., Cooper, Michael K., Packer, Roger J., Massimino, Maura, Garre, Maria Luisa, Bartels, Ute, Dirks, Peter, Bouffet, Eric, Rutka, James T., Wechsler-Reya, Robert J., Weiss, William A., Collier, Lara S., Dupuy, Adam J., Korshunov, Andrey, Jones, David T. W., Kool, Marcel, Northcott, Paul A., Moore, Richard A., Jabado, Nada, Jones, Steven J. M., Malkin, David, Marra, Marco A., Taylor, Michael D.

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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas by Khuong-Quang, Dong-Anh, Buczkowicz, Pawel, Rakopoulos, Patricia, Liu, Xiao-Yang, Fontebasso, Adam M., Bouffet, Eric, Bartels, Ute, Albrecht, Steffen, Schwartzentruber, Jeremy, Letourneau, Louis, Bourgey, Mathieu, Bourque, Guillaume, Montpetit, Alexandre, Bourret, Genevieve, Lepage, Pierre, Fleming, Adam, Lichter, Peter, Kool, Marcel, von Deimling, Andreas, Sturm, Dominik, Korshunov, Andrey, Faury, Damien, Jones, David T., Majewski, Jacek, Pfister, Stefan M., Jabado, Nada, Hawkins, Cynthia

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Optic pathway and hypothalamic glioma, old problems, new paradigms by Yaman Bajin, Inci, Bouffet, Eric

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Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling by Mack, Stephen C., Pajtler, Kristian W., Chavez, Lukas, Okonechnikov, Konstantin, Bertrand, Kelsey C., Wang, Xiuxing, Erkek, Serap, Federation, Alexander, Song, Anne, Lee, Christine, Wang, Xin, McDonald, Laura, Morrow, James J., Saiakhova, Alina, Sin-Chan, Patrick, Wu, Qiulian, Michaelraj, Kulandaimanuvel Antony, Miller, Tyler E., Hubert, Christopher G., Ryzhova, Marina, Garzia, Livia, Donovan, Laura, Dombrowski, Stephen, Factor, Daniel C., Luu, Betty, Valentim, Claudia L. L., Gimple, Ryan C., Morton, Andrew, Kim, Leo, Prager, Briana C., Lee, John J. Y., Wu, Xiaochong, Zuccaro, Jennifer, Thompson, Yuan, Holgado, Borja L., Reimand, Jüri, Ke, Susan Q., Tropper, Adam, Lai, Sisi, Vijayarajah, Senthuran, Doan, Sylvia, Mahadev, Vaidehi, Miñan, Ana Fernandez, Gröbner, Susanne N., Lienhard, Matthias, Zapatka, Marc, Huang, Zhiqin, Aldape, Kenneth D., Carcaboso, Angel M., Houghton, Peter J., Keir, Stephen T., Milde, Till, Witt, Hendrik, Li, Yan, Li, Chao-Jun, Bian, Xiu-Wu, Jones, David T. W., Scott, Ian, Singh, Sheila K., Huang, Annie, Dirks, Peter B., Bouffet, Eric, Bradner, James E., Ramaswamy, Vijay, Jabado, Nada, Rutka, James T., Northcott, Paul A., Lupien, Mathieu, Lichter, Peter, Korshunov, Andrey, Scacheri, Peter C., Pfister, Stefan M., Kool, Marcel, Taylor, Michael D., Rich, Jeremy N.

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Clinical and treatment factors determining long‐term outcomes for adult survivors of childhood low‐grade glioma: A population‐based study by Krishnatry, Rahul, Zhukova, Nataliya, Guerreiro Stucklin, Ana S., Pole, Jason D., Mistry, Matthew, Fried, Iris, Ramaswamy, Vijay, Bartels, Ute, Huang, Annie, Laperriere, Normand, Dirks, Peter, Nathan, Paul C., Greenberg, Mark, Malkin, David, Hawkins, Cynthia, Bandopadhayay, Pratiti, Kieran, Mark W., Manley, Peter E., Bouffet, Eric, Tabori, Uri

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BRAF KIAA1549 Fusion Predicts Better Clinical Outcome in Pediatric Low-Grade Astrocytoma by HAWKING, Cynthia, WALKER, Erin, TSANGARIS, Elena, DIRKS, Peter, TRESSLER, Robert, BOUFFET, Eric, JABADO, Nada, TABORI, Uri, MOHAMED, Nequesha, ZHANG, Cindy, JACOB, Karine, SHIRINIAN, Margret, ALON, Noa, KAHN, Daniel, FRIED, Iris, SCHEINEMANN, Katrin

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Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis by Ramaswamy, Vijay, MD, Remke, Marc, MD, Bouffet, Eric, Prof, Faria, Claudia C, MD, Perreault, Sebastien, MD, Cho, Yoon-Jae, MD, Shih, David J, MSc, Luu, Betty, BSc, Dubuc, Adrian M, PhD, Northcott, Paul A, PhD, Schüller, Ulrich, MD, Gururangan, Sridharan, Prof, McLendon, Roger, Prof, Bigner, Darell, Prof, Fouladi, Maryam, Prof, Ligon, Keith L, MD, Pomeroy, Scott L, Prof, Dunn, Sandra, PhD, Triscott, Joanna, BSc, Jabado, Nada, MD, Fontebasso, Adam, BSc, Jones, David T W, PhD, Kool, Marcel, PhD, Karajannis, Matthias A, MD, Gardner, Sharon L, MD, Zagzag, David, Prof, Nunes, Sofia, MD, Pimentel, José, MD, Mora, Jaume, MD, Lipp, Eric, MD, Walter, Andrew W, MD, Ryzhova, Marina, MD, Zheludkova, Olga, MD, Kumirova, Ella, MD, Alshami, Jad, BSc, Croul, Sidney E, Prof, Rutka, James T, Prof, Hawkins, Cynthia, Prof, Tabori, Uri, MD, Codispoti, Kari-Elise T, MD, Packer, Roger J, Prof, Pfister, Stefan M, Prof, Korshunov, Andrey, Prof, Taylor, Michael D, Prof

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Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost by Zapotocky, Michal, Beera, Kiran, Adamski, Jenny, Laperierre, Normand, Guger, Sharon, Janzen, Laura, Lassaletta, Alvaro, Figueiredo Nobre, Liana, Bartels, Ute, Tabori, Uri, Hawkins, Cynthia, Urbach, Stacey, Tsang, Derek S., Dirks, Peter B., Taylor, Michael D., Bouffet, Eric, Mabbott, Donald J., Ramaswamy, Vijay

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The transcriptional landscape of Shh medulloblastoma by Skowron, Patryk, Farooq, Hamza, Cavalli, Florence M. G., Morrissy, A. Sorana, Ly, Michelle, Hendrikse, Liam D., Wang, Evan Y., Djambazian, Haig, Zhu, Helen, Mungall, Karen L., Trinh, Quang M., Zheng, Tina, Dai, Shizhong, Stucklin, Ana S. Guerreiro, Vladoiu, Maria C., Fong, Vernon, Holgado, Borja L., Nor, Carolina, Wu, Xiaochong, Abd-Rabbo, Diala, Bérubé, Pierre, Wang, Yu Chang, Luu, Betty, Suarez, Raul A., Rastan, Avesta, Gillmor, Aaron H., Lee, John J. Y., Zhang, Xiao Yun, Daniels, Craig, Dirks, Peter, Malkin, David, Bouffet, Eric, Tabori, Uri, Loukides, James, Doz, François P., Bourdeaut, Franck, Delattre, Olivier O., Masliah-Planchon, Julien, Ayrault, Olivier, Kim, Seung-Ki, Meyronet, David, Grajkowska, Wieslawa A., Carlotti, Carlos G., de Torres, Carmen, Mora, Jaume, Eberhart, Charles G., Van Meir, Erwin G., Kumabe, Toshihiro, French, Pim J., Kros, Johan M., Jabado, Nada, Lach, Boleslaw, Pollack, Ian F., Hamilton, Ronald L., Rao, Amulya A. Nageswara, Giannini, Caterina, Olson, James M., Bognár, László, Klekner, Almos, Zitterbart, Karel, Phillips, Joanna J., Thompson, Reid C., Cooper, Michael K., Rubin, Joshua B., Liau, Linda M., Garami, Miklós, Hauser, Peter, Li, Kay Ka Wai, Ng, Ho-Keung, Poon, Wai Sang, Yancey Gillespie, G., Chan, Jennifer A., Jung, Shin, McLendon, Roger E., Thompson, Eric M., Zagzag, David, Vibhakar, Rajeev, Ra, Young Shin, Garre, Maria Luisa, Schüller, Ulrich, Shofuda, Tomoko, Faria, Claudia C., López-Aguilar, Enrique, Zadeh, Gelareh, Hui, Chi-Chung, Ramaswamy, Vijay, Bailey, Swneke D., Jones, Steven J., Mungall, Andrew J., Moore, Richard A., Calarco, John A., Stein, Lincoln D., Bader, Gary D., Reimand, Jüri, Ragoussis, Jiannis, Weiss, William A., Marra, Marco A., Suzuki, Hiromichi, Taylor, Michael D.

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A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor by Sin-Chan, Patrick, Mumal, Iqra, Suwal, Tannu, Ho, Ben, Fan, Xiaolian, Singh, Irtisha, Du, Yuchen, Lu, Mei, Patel, Neilket, Torchia, Jonathon, Popovski, Dean, Fouladi, Maryam, Guilhamon, Paul, Hansford, Jordan R., Leary, Sarah, Hoffman, Lindsey M., Mulcahy Levy, Jean M., Lassaletta, Alvaro, Solano-Paez, Palma, Rivas, Eloy, Reddy, Alyssa, Gillespie, G. Yancey, Gupta, Nalin, Van Meter, Timothy E., Nakamura, Hideo, Wong, Tai-Tong, Ra, Young-Shin, Kim, Seung-Ki, Massimi, Luca, Grundy, Richard G., Fangusaro, Jason, Johnston, Donna, Chan, Jennifer, Lafay-Cousin, Lucie, Hwang, Eugene I., Wang, Yin, Catchpoole, Daniel, Michaud, Jean, Ellezam, Benjamin, Ramanujachar, Ramya, Lindsay, Holly, Taylor, Michael D., Hawkins, Cynthia E., Bouffet, Eric, Jabado, Nada, Singh, Sheila K., Kleinman, Claudia L., Barsyte-Lovejoy, Dalia, Li, Xiao-Nan, Dirks, Peter B., Lin, Charles Y., Mack, Stephen C., Rich, Jeremy N., Huang, Annie

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