Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models by Esteban-Medina, Marina, Peña-Chilet, María, Loucera, Carlos, Dopazo, Joaquín

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Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients by Loucera, Carlos, Peña-Chilet, María, Esteban-Medina, Marina, Muñoyerro-Muñiz, Dolores, Villegas, Román, Lopez-Miranda, Jose, Rodriguez-Baño, Jesus, Túnez, Isaac, Bouillon, Roger, Dopazo, Joaquin, Quesada Gomez, Jose Manuel

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Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models by Payá-Milans, Miriam, Peña-Chilet, María, Loucera, Carlos, Esteban-Medina, Marina, Dopazo, Joaquín

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The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery by Esteban-Medina, Marina, Loucera, Carlos, Rian, Kinza, Velasco, Sheyla, Olivares-González, Lorena, Rodrigo, Regina, Dopazo, Joaquin, Peña-Chilet, Maria

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Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments by Loucera, Carlos, Carmona, Rosario, Esteban-Medina, Marina, Bostelmann, Gerrit, Muéoyerro-Muéiz, Dolores, Villegas, Román, Peéa-Chilet, María, Dopazo, Joaquín

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Nutraceutical supplementation in inherited retinal dystrophies by Velasco, Sheyla, Olivares‐González, Lorena, Morales, Silvia, Valencia, Daira, Esteban‐Medina, Marina, Loucera, Carlos, Salom, David, García, Emilio González, Castillo, Jose Miguel Soriano, Rodrigo, Regina

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Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection by Loucera, Carlos, Esteban-Medina, Marina, Rian, Kinza, Falco, Matías M., Dopazo, Joaquín, Peña-Chilet, María

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drexml: A command line tool and Python package for drug repurposing by Esteban-Medina, Marina, de la Oliva Roque, Víctor Manuel, Herráiz-Gil, Sara, Peña-Chilet, María, Dopazo, Joaquín, Loucera, Carlos

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Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell–Matrix Interactions by Puerto-Camacho, Pilar, Díaz-Martín, Juan, Olmedo-Pelayo, Joaquín, Bolado-Carrancio, Alfonso, Salguero-Aranda, Carmen, Jordán-Pérez, Carmen, Esteban-Medina, Marina, Álamo-Álvarez, Inmaculada, Delgado-Bellido, Daniel, Lobo-Selma, Laura, Dopazo, Joaquín, Sastre, Ana, Alonso, Javier, Grünewald, Thomas G. P., Bernabeu, Carmelo, Byron, Adam, Brunton, Valerie G., Amaral, Ana Teresa, Álava, Enrique De

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Mechanistic modeling of the SARS-CoV-2 disease map by Rian, Kinza, Esteban-Medina, Marina, Hidalgo, Marta R, Çubuk, Cankut, Falco, Matias M, Loucera, Carlos, Gunyel, Devrim, Ostaszewski, Marek, Peña-Chilet, María, Dopazo, Joaquín

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An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice by Olivares-González, Lorena, Velasco, Sheyla, Gallego, Idoia, Esteban-Medina, Marina, Puras, Gustavo, Loucera, Carlos, Martínez-Romero, Alicia, Peña-Chilet, María, Pedraz, José Luis, Rodrigo, Regina

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Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data by Rian, Kinza, Hidalgo, Marta R., Çubuk, Cankut, Falco, Matias M., Loucera, Carlos, Esteban-Medina, Marina, Alamo-Alvarez, Inmaculada, Peña-Chilet, María, Dopazo, Joaquín

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Visualization of automatically combined disease maps and pathway diagrams for rare diseases by Gawron, Piotr, Hoksza, David, Piñero, Janet, Peña-Chilet, Maria, Esteban-Medina, Marina, Fernandez-Rueda, Jose Luis, Colonna, Vincenza, Smula, Ewa, Heirendt, Laurent, Ancien, François, Groues, Valentin, Satagopam, Venkata P, Schneider, Reinhard, Dopazo, Joaquin, Furlong, Laura I, Ostaszewski, Marek

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Using mechanistic models for the clinical interpretation of complex genomic variation by Peña-Chilet, María, Esteban-Medina, Marina, Falco, Matias M., Rian, Kinza, Hidalgo, Marta R., Loucera, Carlos, Dopazo, Joaquín

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Abstract 6158: The relevance of endoglin and MMP14 to the metastatic potential of Ewing sarcoma cells by Puerto-Camacho, Pilar, Amaral, Ana Teresa, Diaz-Martin, Juan, Bolado-Carrancio, Alfonso, Jordan-Perez, Carmen, Salguero-Aranda, Carmen, Esteban-Medina, Marina, Alamo-Alvarez, Inmaculada, Dopazo, Joaquin, Bernabeu, Carmelo, Byron, Adam, Brunton, Valerie G., de Álava, Enrique

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Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches by Niarakis, Anna, Ostaszewski, Marek, Mazein, Alexander, Kuperstein, Inna, Kutmon, Martina, Gillespie, Marc E, Funahashi, Akira, Acencio, Marcio Luis, Hemedan, Ahmed, Aichem, Michael, Klein, Karsten, Czauderna, Tobias, Burtscher, Felicia, Yamada, Takahiro G, Hiki, Yusuke, Hiroi, Noriko F, Hu, Finterly, Pham, Nhung, Ehrhart, Friederike, Willighagen, Egon L, Valdeolivas, Alberto, Dugourd, Aurelien, Messina, Francesco, Esteban-Medina, Marina, Peña-Chilet, Maria, Rian, Kinza, Soliman, Sylvain, Aghamiri, Sara Sadat, Puniya, Bhanwar Lal, Naldi, Aurélien, Helikar, Tomáš, Singh, Vidisha, Fernández, Marco Fariñas, Bermudez, Viviam, Tsirvouli, Eirini, Montagud, Arnau, Noël, Vincent, Ponce-de-Leon, Miguel, Maier, Dieter, Bauch, Angela, Gyori, Benjamin M, Bachman, John A, Luna, Augustin, Piñero, Janet, Furlong, Laura I, Balaur, Irina, Rougny, Adrien, Jarosz, Yohan, Overall, Rupert W, Phair, Robert, Perfetto, Livia, Matthews, Lisa, Rex, Devasahayam Arokia Balaya, Orlic-Milacic, Marija, Gomez, Luis Cristobal Monraz, De Meulder, Bertrand, Ravel, Jean Marie, Jassal, Bijay, Satagopam, Venkata, Wu, Guanming, Golebiewski, Martin, Gawron, Piotr, Calzone, Laurence, Beckmann, Jacques S, Evelo, Chris T, D'Eustachio, Peter, Schreiber, Falk, Saez-Rodriguez, Julio, Dopazo, Joaquin, Kuiper, Martin, Valencia, Alfonso, Wolkenhauer, Olaf, Kitano, Hiroaki, Barillot, Emmanuel, Auffray, Charles, Balling, Rudi, Schneider, Reinhard

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COVID‐19 Disease Map, a computational knowledge repository of virus‐host interaction mechanisms by Niarakis, Anna, Kuperstein, Inna, Orta‐Resendiz, Aurelio, Singh, Vidisha, Aghamiri, Sara Sadat, Acencio, Marcio Luis, Glaab, Enrico, Ruepp, Andreas, Montrone, Corinna, Monraz Gómez, Luis Cristóbal, Somers, Julia, Hoch, Matti, Scheel, Julia, Borlinghaus, Hanna, Schreiber, Falk, Montagud, Arnau, Funahashi, Akira, Hiki, Yusuke, Yamada, Takahiro G, Renz, Alina, Naveez, Muhammad, Bocskei, Zsolt, Messina, Francesco, Börnigen, Daniela, Fergusson, Liam, Conti, Marta, Rameil, Marius, Nakonecnij, Vanessa, Vanhoefer, Jakob, Schmiester, Leonard, Wang, Muying, Ackerman, Emily E, Shoemaker, Jason E, Oxford, Kristie, Teuton, Jeremy, Kocakaya, Ebru, Summak, Gökçe Yağmur, Hanspers, Kristina, Kutmon, Martina, Coort, Susan, Ehrhart, Friederike, Martens, Marvin, Pham, Nhung, Haw, Robin, Jassal, Bijay, Matthews, Lisa, Senff‐Ribeiro, Andrea, Rothfels, Karen, Shamovsky, Veronica, Stephan, Ralf, Sevilla, Cristoffer, Varusai, Thawfeek, Ravel, Jean‐Marie, Fraser, Rupsha, Smula, Ewa, Heirendt, Laurent, Satagopam, Venkata, Owen, Stuart, Goble, Carole, Hu, Xiaoming, Maier, Dieter, Bauch, Angela, Gyori, Benjamin M, Bachman, John A, Vega, Carlos, Grouès, Valentin, Porras, Pablo, Licata, Luana, Sacco, Francesca, Nesterova, Anastasia, Turei, Denes, Luna, Augustin, Babur, Ozgun, Soliman, Sylvain, Peña‐Chilet, Maria, Rian, Kinza, Helikar, Tomáš, Modos, Dezso, Treveil, Agatha, Olbei, Marton, De Meulder, Bertrand, Ballereau, Stephane, Dugourd, Aurélien, Naldi, Aurélien, Noël, Vincent, Calzone, Laurence, Sander, Chris, Demir, Emek, Korcsmaros, Tamas, Beckmann, Jacques S, Hasenauer, Jan, Wolkenhauer, Olaf, Willighagen, Egon L, Evelo, Chris T, Gillespie, Marc E, Valencia, Alfonso, Kitano, Hiroaki, Auffray, Charles, Balling, Rudi, Schneider, Reinhard

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Immune digital twins for complex human pathologies: applications, limitations, and challenges by Niarakis, Anna, Laubenbacher, Reinhard, An, Gary, Ilan, Yaron, Fisher, Jasmin, Flobak, Åsmund, Reiche, Kristin, Rodríguez Martínez, María, Geris, Liesbet, Ladeira, Luiz, Veschini, Lorenzo, Blinov, Michael L., Messina, Francesco, Fonseca, Luis L., Ferreira, Sandra, Montagud, Arnau, Noël, Vincent, Marku, Malvina, Tsirvouli, Eirini, Torres, Marcella M., Harris, Leonard A., Sego, T. J., Cockrell, Chase, Shick, Amanda E., Balci, Hasan, Salazar, Albin, Rian, Kinza, Hemedan, Ahmed Abdelmonem, Esteban-Medina, Marina, Staumont, Bernard, Hernandez-Vargas, Esteban, Martis B, Shiny, Madrid-Valiente, Alejandro, Karampelesis, Panagiotis, Sordo Vieira, Luis, Harlapur, Pradyumna, Kulesza, Alexander, Nikaein, Niloofar, Garira, Winston, Malik Sheriff, Rahuman S., Thakar, Juilee, Tran, Van Du T., Carbonell-Caballero, Jose, Safaei, Soroush, Valencia, Alfonso, Zinovyev, Andrei, Glazier, James A.

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Mechanistic modeling of the SARS-CoV-2 disease map by Kinza Rian, Esteban-Medina, Marina, Hidalgo, Marta R, Çubuk, Cankut, Falco, Matias M, Loucera, Carlos, Gunyel, Devrim, Ostaszewski, Marek, Peña-Chilet, María, Dopazo, Joaquin

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Mechanistic modeling of the SARS-CoV-2 disease map by Kinza Rian, Esteban-Medina, Marina, Hidalgo, Marta R, Cubuk, Cankut, Falco, Matias M, Loucera, Carlos, Gunyel, Devrim, Ostaszewski, Marek, Pena-Chilet, Maria, Dopazo, Joaquin

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