USP11 Enhances TGFβ-Induced Epithelial-Mesenchymal Plasticity and Human Breast Cancer Metastasis by Garcia, Daniel A, Baek, Christina, Estrada, M Valeria, Tysl, Tiffani, Bennett, Eric J, Yang, Jing, Chang, John T

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Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer by Hanna, Ann, Nixon, Mellissa J, Estrada, M Valeria, Sanchez, Violeta, Sheng, Quanhu, Opalenik, Susan R, Toren, Abigail L, Bauer, Joshua, Owens, Phillip, Mason, Frank M, Cook, Rebecca S, Sanders, Melinda E, Arteaga, Carlos L, Balko, Justin M

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Pembrolizumab plus cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma: an open-label, multi-arm, non-randomised, multicentre, phase 2 trial by Sacco, Assuntina G, Chen, Ruifeng, Worden, Francis P, Wong, Deborah J L, Adkins, Douglas, Swiecicki, Paul, Chai-Ho, Wanxing, Oppelt, Peter, Ghosh, Debanjali, Bykowski, Julie, Molinolo, Alfredo, Pittman, Emily, Estrada, M Valeria, Gold, Kathryn, Daniels, Gregory, Lippman, Scott M, Natsuhara, Amanda, Messer, Karen, Cohen, Ezra E W

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PIK3CA and MAP3K1 alterations imply luminal A status and are associated with clinical benefit from pan-PI3K inhibitor buparlisib and letrozole in ER+ metastatic breast cancer by Nixon, Mellissa J., Formisano, Luigi, Mayer, Ingrid A., Estrada, M. Valeria, González-Ericsson, Paula I., Isakoff, Steven J., Forero-Torres, Andrés, Won, Helen, Sanders, Melinda E., Solit, David B., Berger, Michael F., Cantley, Lewis C., Winer, Eric P., Arteaga, Carlos L., Balko, Justin M.

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The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group by El Bairi, Khalid, Haynes, Harry R., Blackley, Elizabeth, Fineberg, Susan, Shear, Jeffrey, Turner, Sophia, de Freitas, Juliana Ribeiro, Sur, Daniel, Amendola, Luis Claudio, Gharib, Masoumeh, Kallala, Amine, Arun, Indu, Azmoudeh-Ardalan, Farid, Fujimoto, Luciana, Sua, Luz F., Liu, Shi-Wei, Lien, Huang-Chun, Kirtani, Pawan, Balancin, Marcelo, El Attar, Hicham, Guleria, Prerna, Yang, Wenxian, Shash, Emad, Chen, I-Chun, Bautista, Veronica, Do Prado Moura, Jose Fernando, Rapoport, Bernardo L., Castaneda, Carlos, Spengler, Eunice, Acosta-Haab, Gabriela, Frahm, Isabel, Sanchez, Joselyn, Castillo, Miluska, Bouchmaa, Najat, Md Zin, Reena R., Shui, Ruohong, Onyuma, Timothy, Yang, Wentao, Husain, Zaheed, Willard-Gallo, Karen, Coosemans, An, Perez, Edith A., Provenzano, Elena, Ericsson, Paula Gonzalez, Richardet, Eduardo, Mehrotra, Ravi, Sarancone, Sandra, Ehinger, Anna, Rimm, David L., Bartlett, John M. S., Viale, Giuseppe, Denkert, Carsten, Hida, Akira I., Sotiriou, Christos, Loibl, Sibylle, Hewitt, Stephen M., Badve, Sunil, Symmans, William Fraser, Kim, Rim S., Pruneri, Giancarlo, Goel, Shom, Francis, Prudence A., Inurrigarro, Gloria, Yamaguchi, Rin, Garcia-Rivello, Hernan, Horlings, Hugo, Afqir, Said, Salgado, Roberto, Adams, Sylvia, Kok, Marleen, Dieci, Maria Vittoria, Michiels, Stefan, Demaria, Sandra, Loi, Sherene

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Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer by Kos, Zuzana, Roblin, Elvire, Kim, Rim S., Michiels, Stefan, Gallas, Brandon D., Chen, Weijie, van de Vijver, Koen K., Goel, Shom, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O., Badve, Sunil S., Symmans, W. Fraser, Sotiriou, Christos, Rimm, David L., Hewitt, Stephen, Denkert, Carsten, Loibl, Sibylle, Luen, Stephen J., Bartlett, John M. S., Savas, Peter, Pruneri, Giancarlo, Dillon, Deborah A., Cheang, Maggie Chon U., Tutt, Andrew, Hall, Jacqueline A., Kok, Marleen, Horlings, Hugo M., Madabhushi, Anant, van der Laak, Jeroen, Ciompi, Francesco, Laenkholm, Anne-Vibeke, Bellolio, Enrique, Gruosso, Tina, Fox, Stephen B., Araya, Juan Carlos, Floris, Giuseppe, Hudeček, Jan, Voorwerk, Leonie, Beck, Andrew H., Kerner, Jen, Larsimont, Denis, Declercq, Sabine, Van den Eynden, Gert, Pusztai, Lajos, Ehinger, Anna, Yang, Wentao, AbdulJabbar, Khalid, Yuan, Yinyin, Singh, Rajendra, Hiley, Crispin, Bakir, Maise al, Lazar, Alexander J., Naber, Stephen, Wienert, Stephan, Castillo, Miluska, Curigliano, Giuseppe, Dieci, Maria-Vittoria, André, Fabrice, Swanton, Charles, Reis-Filho, Jorge, Sparano, Joseph, Balslev, Eva, Chen, I-Chun, Stovgaard, Elisabeth Ida Specht, Pogue-Geile, Katherine, Blenman, Kim R. M., Penault-Llorca, Frédérique, Schnitt, Stuart, Lakhani, Sunil R., Vincent-Salomon, Anne, Rojo, Federico, Braybrooke, Jeremy P., Hanna, Matthew G., Soler-Monsó, M. Teresa, Bethmann, Daniel, Castaneda, Carlos A., Willard-Gallo, Karen, Sharma, Ashish, Lien, Huang-Chun, Fineberg, Susan, Thagaard, Jeppe, Comerma, Laura, Gonzalez-Ericsson, Paula, Brogi, Edi, Loi, Sherene, Saltz, Joel, Klaushen, Frederick, Cooper, Lee, Amgad, Mohamed, Moore, David A., Salgado, Roberto

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ER + Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors by Guerrero-Zotano, Angel L, Stricker, Thomas P, Formisano, Luigi, Hutchinson, Katherine E, Stover, Daniel G, Lee, Kyung-Min, Schwarz, Luis J, Giltnane, Jennifer M, Estrada, Monica V, Jansen, Valerie M, Servetto, Alberto, Gavilá, Joaquín, Perez-Fidalgo, J Alejandro, Lluch, Ana, Llombart-Cussac, Antonio, Bayar, Mohamed Amine, Michiels, Stefan, André, Fabrice, Arnedos, Mónica, Guillem, Vicente, Ruiz-Simon, Amparo, Arteaga, Carlos L

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Abstract B28: Rictor/mTORC2 drives formation, progression, and therapeutic resistance of HER2-amplified breast cancers by Morrison, Meghan M., Jones, Bayley A., Hicks, Donna J., Sanchez, Violeta, Estrada, Valeria M., Williams, Michelle M., Brantley-Sieders, Dana, Cook, Rebecca S.

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Abstract 5008: The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation by Ferraro, Gino B., Kodack, David P., Askoxylakis, Vasileios, Sheng, Qing, Badeaux, Mark, Goel, Shom, Qi, Xiaolong, Shankaraiah, Ram, Cao, Alexander Z., Ramjiawan, Rakesh R., Bezwada, Divya, Patel, Bhushankumar, Song, Youngchul, Costa, Carlotta, Naxerova, Kamila, Wong, Christina, Kloepper, Jonas, Das, Rita, Tam, Angela, Tanboon, Jantima, Duda, Dan G., Miller, Ryan C., Siegel, Marni B., Anders, Carey K., Sanders, Melinda, Estrada, Valeria M., Schlegel, Robert, Arteaga, Carlos L., Brachtel, Elena, Huang, Alan, Fukumura, Dai, Engelman, Jeffrey A., Jain, Rakesh K.

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Abstract PD6-3: Recurrent ESR1 fusion transcripts are associated with endocrine resistance in estrogen receptor positive, HER2 negative breast cancer by Giltnane, Jennifer M, Balko, Justin M, Stricker, Thomas L, Young, Christian, Estrada, M Valeria, Wagle, Nikhil, van Allen, Eliezer, Mu, X Jasmine, Sanchez, Violeta, Farley, Jaime, Fitzgerald, Kerry, Graber, Armin, Pinto, Joseph A, Doimi, Franco, Gómez, Henry, Rizzo, Monica, Julian, Thomas B, Abramson, Vandana, Mayer, Ingrid, Kelley, Mark, Yenamandra, Ashwini, Wheeler, Ferrin C, Sanders, Melinda, Garraway, Levi, Meszoely, Ingrid, Arteaga, Carlos L

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Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer by Kos, Zuzana, Roblin, Elvire, Kim, Rim S, Michiels, Stefan, Gallas, Brandon D, Chen, Weijie, van de Vijver, Koen K, Goel, Shom, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O, Badve, Sunil S, Symmans, W Fraser, Sotiriou, Christos, Rimm, David L, Hewitt, Stephen, Denkert, Carsten, Loibl, Sibylle, Luen, Stephen J, Bartlett, John M S, Savas, Peter, Pruneri, Giancarlo, Dillon, Deborah A, Cheang, Maggie Chon U, Tutt, Andrew, Hall, Jacqueline A, Kok, Marleen, Horlings, Hugo M, Madabhushi, Anant, van der Laak, Jeroen, Ciompi, Francesco, Laenkholm, Anne-Vibeke, Bellolio, Enrique, Gruosso, Tina, Fox, Stephen B, Araya, Juan Carlos, Floris, Giuseppe, Hudeček, Jan, Voorwerk, Leonie, Beck, Andrew H, Kerner, Jen, Larsimont, Denis, Declercq, Sabine, Van den Eynden, Gert, Pusztai, Lajos, Ehinger, Anna, Yang, Wentao, AbdulJabbar, Khalid, Yuan, Yinyin, Singh, Rajendra, Hiley, Crispin, Bakir, Maise Al, Lazar, Alexander J, Naber, Stephen, Wienert, Stephan, Castillo, Miluska, Curigliano, Giuseppe, Dieci, Maria-Vittoria, André, Fabrice, Swanton, Charles, Reis-Filho, Jorge, Sparano, Joseph, Balslev, Eva, Chen, I-Chun, Stovgaard, Elisabeth Ida Specht, Pogue-Geile, Katherine, Blenman, Kim R M, Penault-Llorca, Frédérique, Schnitt, Stuart, Lakhani, Sunil R, Vincent-Salomon, Anne, Rojo, Federico, Braybrooke, Jeremy P, Hanna, Matthew G, Soler-Monsó, M Teresa, Bethmann, Daniel, Castaneda, Carlos A, Willard-Gallo, Karen, Sharma, Ashish, Lien, Huang-Chun, Fineberg, Susan, Thagaard, Jeppe, Comerma, Laura, Gonzalez-Ericsson, Paula, Brogi, Edi, Loi, Sherene, Saltz, Joel, Klaushen, Frederick, Cooper, Lee, Amgad, Mohamed, Moore, David A, Salgado, Roberto

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HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2 by Hanker, Ariella B, Garrett, Joan T, Estrada, Mónica Valeria, Moore, Preston D, Ericsson, Paula González, Koch, James P, Langley, Emma, Singh, Sharat, Kim, Phillip S, Frampton, Garrett M, Sanford, Eric, Owens, Philip, Becker, Jennifer, Groseclose, M Reid, Castellino, Stephen, Joensuu, Heikki, Huober, Jens, Brase, Jan C, Majjaj, Samira, Brohée, Sylvain, Venet, David, Brown, David, Baselga, José, Piccart, Martine, Sotiriou, Christos, Arteaga, Carlos L

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Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging by Bhaskar, Sonu, Tian, Furong, Stoeger, Tobias, Kreyling, Wolfgang, de la Fuente, Jesús M, Grazú, Valeria, Borm, Paul, Estrada, Giovani, Ntziachristos, Vasilis, Razansky, Daniel

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Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER + Breast Cancer by Formisano, Luigi, Stauffer, Kimberly M, Young, Christian D, Bhola, Neil E, Guerrero-Zotano, Angel L, Jansen, Valerie M, Estrada, Mónica M, Hutchinson, Katherine E, Giltnane, Jennifer M, Schwarz, Luis J, Lu, Yao, Balko, Justin M, Deas, Olivier, Cairo, Stefano, Judde, Jean-Gabriel, Mayer, Ingrid A, Sanders, Melinda, Dugger, Teresa C, Bianco, Roberto, Stricker, Thomas, Arteaga, Carlos L

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Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer by Jansen, Valerie M, Bhola, Neil E, Bauer, Joshua A, Formisano, Luigi, Lee, Kyung-Min, Hutchinson, Katherine E, Witkiewicz, Agnieszka K, Moore, Preston D, Estrada, Mónica Valéria, Sánchez, Violeta, Ericsson, Paula G, Sanders, Melinda E, Pohlmann, Paula R, Pishvaian, Michael J, Riddle, David A, Dugger, Teresa C, Wei, Wenyi, Knudsen, Erik S, Arteaga, Carlos L

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Single neurons may encode simultaneous stimuli by switching between activity patterns by Caruso, Valeria C., Mohl, Jeff T., Glynn, Christopher, Lee, Jungah, Willett, Shawn M., Zaman, Azeem, Ebihara, Akinori F., Estrada, Rolando, Freiwald, Winrich A., Tokdar, Surya T., Groh, Jennifer M.

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FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer by Tai, Yifan, Chow, Angela, Han, Seoyoung, Coker, Courtney, Ma, Wanchao, Gu, Yifan, Estrada Navarro, Valeria, Kandpal, Manoj, Hibshoosh, Hanina, Kalinsky, Kevin, Manova-Todorova, Katia, Safonov, Anton, Walsh, Elaine M, Robson, Mark, Norton, Larry, Baer, Richard, Merghoub, Taha, Biswas, Anup K, Acharyya, Swarnali

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Rituximab Therapy in Refractory Neuropsychiatric Lupus: Current Clinical Evidence by Narváez, Javier, MD, PhD, Ríos-Rodriguez, Valeria, MD, de la Fuente, Diana, MD, Estrada, Paula, MD, López-Vives, Laura, MD, Gómez-Vaquero, Carmen, MD, PhD, Nolla, Joan Miquel, MD, PhD

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Biological Control Mechanisms of Bacillus cabrialesii subsp. tritici TSO2T against Fusarium languescens, the Causal Agent of Wilt in Jalapeño Peppers by Montoya-Martínez, Amelia C., Figueroa-Brambila, Karem M., Escalante-Beltrán, Alina, López-Montoya, Naomi D., Valenzuela-Ruíz, Valeria, Parra-Cota, Fannie I., Estrada Alvarado, María Isabel, de los Santos-Villalobos, Sergio

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Long-term exposure to house dust mites accelerates lung cancer development in mice by Wang, Dongjie, Li, Wen, Albasha, Natalie, Griffin, Lindsey, Chang, Han, Amaya, Lauren, Ganguly, Sneha, Zeng, Liping, Keum, Bora, González-Navajas, José M, Levin, Matt, AkhavanAghdam, Zohreh, Snyder, Helen, Schwartz, David, Tao, Ailin, Boosherhri, Laela M, Hoffman, Hal M, Rose, Michael, Estrada, Monica Valeria, Varki, Nissi, Herdman, Scott, Corr, Maripat, Webster, Nicholas J G, Raz, Eyal, Bertin, Samuel

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