Small-molecule inhibitors targeting G-protein–coupled Rho guanine nucleotide exchange factors by Shang, Xun, Marchioni, Fillipo, Evelyn, Chris R., Sipes, Nisha, Zhou, Xuan, Seibel, William, Wortman, Matthew, Zheng, Yi

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Small-Molecule Targeting of Proliferating Cell Nuclear Antigen Chromatin Association Inhibits Tumor Cell Growth by Tan, Zongqing, Wortman, Matthew, Dillehay, Kelsey L., Seibel, William L., Evelyn, Chris R., Smith, Shanna J., Malkas, Linda H., Zheng, Yi, Lu, Shan, Dong, Zhongyun

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Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance by Kesarwani, Meenu, Huber, Erika, Kincaid, Zachary, Evelyn, Chris R., Biesiada, Jacek, Rance, Mark, Thapa, Mahendra B., Shah, Neil P., Meller, Jarek, Zheng, Yi, Azam, Mohammad

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CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling by Evelyn, Chris R, Wade, Susan M, Wang, Qin, Wu, Mei, Iñiguez-Lluhí, Jorge A, Merajver, Sofia D, Neubig, Richard R

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Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423 by Evelyn, Chris R., Bell, Jessica L., Ryu, Jenny G., Wade, Susan M., Kocab, Andrew, Harzdorf, Nicole L., Hollis Showalter, H.D., Neubig, Richard R., Larsen, Scott D.

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A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells by Aittaleb, Mohamed, Gao, Guang, Evelyn, Chris R., Neubig, Richard R., Tesmer, John J.G.

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Combined Rational Design and a High Throughput Screening Platform for Identifying Chemical Inhibitors of a Ras-activating Enzyme by Evelyn, Chris R., Biesiada, Jacek, Duan, Xin, Tang, Hong, Shang, Xun, Papoian, Ruben, Seibel, William L., Nelson, Sandra, Meller, Jaroslaw, Zheng, Yi

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Structure of Gαq-p63RhoGEF-RhoA Complex Reveals a Pathway for the Activation of RhoA by GPCRs by Lutz, Susanne, Shankaranarayanan, Aruna, Coco, Cassandra, Ridilla, Marc, Nance, Mark R, Vettel, Christiane, Baltus, Doris, Evelyn, Chris R, Neubig, Richard R, Wieland, Thomas, Tesmer, John J.G

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High-Throughput Screening for Small-Molecule Inhibitors of LARG-Stimulated RhoA Nucleotide Binding via a Novel Fluorescence Polarization Assay by Evelyn, Chris R., Ferng, Timothy, Rojas, Rafael J., Larsen, Martha J., Sondek, John, Neubig, Richard R.

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Structure of G[alpha]q-p63RhoGEF-RhoA Complex Reveals a Pathway for the Activation of RhoA by GPCRs by Lutz, Susanne, Shankaranarayanan, Aruna, Coco, Cassandra, Ridilla, Marc, Nance, Mark R, Vettel, Christiane, Baltus, Doris, Evelyn, Chris R, Neubig, Richard R, Wieland, Thomas, Tesmer, John J G

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Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks by Evelyn, Chris R, Lisabeth, Erika M, Wade, Susan M, Haak, Andrew J, Johnson, Craig N, Lawlor, Elizabeth R, Neubig, Richard R

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Structure of$\text{G}\alpha _{\text{q}}-\text{p}63\text{RhoGEF}-\text{RhoA}$Complex Reveals a Pathway for the Activation of RhoA by GPCRs by Lutz, Susanne, Shankaranarayanan, Aruna, Coco, Cassandra, Ridilla, Marc, Nance, Mark R., Vettel, Christiane, Baltus, Doris, Evelyn, Chris R., Neubig, Richard R., Wieland, Thomas, Tesmer, John J. G.

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Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs by Lutz, Susanne, Shankaranarayanan, Aruna, Coco, Cassandra, Ridilla, Marc, Nance, Mark R, Vettel, Christiane, Baltus, Doris, Evelyn, Chris R, Neubig, Richard R, Wieland, Thomas, Tesmer, John J G

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The antimicrobial potential of Streptomyces from insect microbiomes by Chevrette, Marc G., Carlson, Caitlin M., Ortega, Humberto E., Thomas, Chris, Ananiev, Gene E., Barns, Kenneth J., Book, Adam J., Cagnazzo, Julian, Carlos, Camila, Flanigan, Will, Grubbs, Kirk J., Horn, Heidi A., Hoffmann, F. Michael, Klassen, Jonathan L., Knack, Jennifer J., Lewin, Gina R., McDonald, Bradon R., Muller, Laura, Melo, Weilan G. P., Pinto-Tomás, Adrián A., Schmitz, Amber, Wendt-Pienkowski, Evelyn, Wildman, Scott, Zhao, Miao, Zhang, Fan, Bugni, Tim S., Andes, David R., Pupo, Monica T., Currie, Cameron R.

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Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients by de Sousa E Melo, Felipe, Colak, Selcuk, Buikhuisen, Joyce, Koster, Jan, Cameron, Kate, de Jong, Joan H., Tuynman, Jurriaan B., Prasetyanti, Pramudita R., Fessler, Evelyn, van den Bergh, Saskia P., Rodermond, Hans, Dekker, Evelien, van der Loos, Chris M., Pals, Steven T., van de Vijver, Marc J., Versteeg, Rogier, Richel, Dick J., Vermeulen, Louis, Medema, Jan Paul

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Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis by Tacconelli, Evelina, Carrara, Elena, Savoldi, Alessia, Harbarth, Stephan, Mendelson, Marc, Monnet, Dominique L, Pulcini, Céline, Kahlmeter, Gunnar, Kluytmans, Jan, Carmeli, Yehuda, Ouellette, Marc, Outterson, Kevin, Patel, Jean, Cavaleri, Marco, Cox, Edward M, Houchens, Chris R, Grayson, M Lindsay, Hansen, Paul, Singh, Nalini, Theuretzbacher, Ursula, Magrini, Nicola, Aboderin, Aaron Oladipo, Al-Abri, Seif Salem, Awang Jalil, Nordiah, Benzonana, Nur, Bhattacharya, Sanjay, Brink, Adrian John, Burkert, Francesco Robert, Cars, Otto, Cornaglia, Giuseppe, Dyar, Oliver James, Friedrich, Alex W, Gales, Ana C, Gandra, Sumanth, Giske, Christian Georg, Goff, Debra A, Goossens, Herman, Gottlieb, Thomas, Guzman Blanco, Manuel, Hryniewicz, Waleria, Kattula, Deepthi, Jinks, Timothy, Kanj, Souha S, Kerr, Lawrence, Kieny, Marie-Paule, Kim, Yang Soo, Kozlov, Roman S, Labarca, Jaime, Laxminarayan, Ramanan, Leder, Karin, Leibovici, Leonard, Levy-Hara, Gabriel, Littman, Jasper, Malhotra-Kumar, Surbhi, Manchanda, Vikas, Moja, Lorenzo, Ndoye, Babacar, Pan, Angelo, Paterson, David L, Paul, Mical, Qiu, Haibo, Ramon-Pardo, Pilar, Rodríguez-Baño, Jesús, Sanguinetti, Maurizio, Sengupta, Sharmila, Sharland, Mike, Si-Mehand, Massinissa, Silver, Lynn L, Song, Wonkeung, Steinbakk, Martin, Thomsen, Jens, Thwaites, Guy E, van der Meer, Jos WM, Van Kinh, Nguyen, Vega, Silvio, Villegas, Maria Virginia, Wechsler-Fördös, Agnes, Wertheim, Heiman Frank Louis, Wesangula, Evelyn, Woodford, Neil, Yilmaz, Fidan O, Zorzet, Anna

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Where and with whom does a brief social-belonging intervention promote progress in college? by Walton, Gregory M, Murphy, Mary C, Logel, Christine, Yeager, David S, Goyer, J Parker, Brady, Shannon T, Emerson, Katherine T U, Paunesku, David, Fotuhi, Omid, Blodorn, Alison, Boucher, Kathryn L, Carter, Evelyn R, Gopalan, Maithreyi, Henderson, Amy, Kroeper, Kathryn M, Murdock-Perriera, Lisel Alice, Reeves, Stephanie L, Ablorh, Tsotso T, Ansari, Shahana, Chen, Susie, Fisher, Peter, Galvan, Manuel, Gilbertson, Madison Kawakami, Hulleman, Chris S, Le Forestier, Joel M, Lok, Christopher, Mathias, Katie, Muragishi, Gregg A, Netter, Melanie, Ozier, Elise, Smith, Eric N, Thoman, Dustin B, Williams, Heidi E, Wilmot, Matthew O, Hartzog, Cassie, Li, X Alice, Krol, Natasha

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Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals by Howrigan, Daniel P., Abbott, Liam E., Tashman, Katherine, Singh, Tarjinder, Watts, Nick, Lal, Dennis, Hakonarson, Hakon, Weckhuysen, Sarah, Petrovski, Slavé, Cossette, Patrick, Cotsapas, Chris, De Jonghe, Peter, Guerrini, Renzo, Marson, Anthony G., Depondt, Chantal, Striano, Pasquale, Freyer, Catharine, Regan, Brigid M., Leu, Costin, Johns, Esther M.C., Macdonald, Alexandra, Bahlo, Melanie, Todaro, Marian, Stamberger, Hannah, Sadoway, Tara R., Kousiappa, Ioanna, Tanteles, George A., Štěrbová, Katalin, Kunz, Wolfram S., Zsurka, Gábor, Elger, Christian E., Rademacher, Michael, van Baalen, Andreas, von Spiczak, Sarah, Afawi, Zaid, Canavati, Christina, Kluger, Gerhard, Blatt, Ilan, Weber, Yvonne G., Wolking, Stefan, Rau, Sarah, Steinhoff, Bernhard J., Schulze-Bonhage, Andreas, Borggräfe, Ingo, Madeleyn, Rene, Kälviäinen, Reetta, Linnankivi, Tarja, Chung, Seo-Kyung, Balestrini, Simona, Braatz, Vera, Johnson, Michael R., Auce, Pauls, Sham, Pak C., Lui, Colin H.T., Doherty, Colin P., Shukralla, Arif, El-Naggar, Hany, Vari, Maria Stella, Salpietro, Vincenzo, Tinuper, Paolo, Gagliardi, Monica, Montomoli, Martino, Doccini, Viola, Inoue, Yushi, Yamakawa, Kazuhiro, Tumiene, Birute, Sadleir, Lynette G., Caglayan, S. Hande, Arslan, Mutluay, Yis, Uluc, Topaloglu, Pınar, Baykan, Betül, Salman, Barış, Haryanyan, Garen, Özkara, Çiğdem, Poduri, Annapurna, Shiedley, Beth R., Shain, Catherine, French, Jacqueline A., Kuzniecky, Ruben I., Hegde, Manu, Helbig, Katherine L., Piras, Federica, Reif, Andreas, McQuillin, Andrew, Johnstone, Mandy, Palotie, Aarno, Carvalho, Celia Barreto, Achtyes, Eric D., Azevedo, Maria Helena, Kotov, Roman, Lehrer, Douglas S., Marder, Stephen R., Medeiros, Helena, Morley, Christopher P., Rapaport, Mark H., Knowles, James A., McCarroll, Steven A., Lowenstein, Daniel H., Goldstein, David B.

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Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease by Jostins, Luke, Ripke, Stephan, Weersma, Rinse K., Duerr, Richard H., McGovern, Dermot P., Hui, Ken Y., Lee, James C., Philip Schumm, L., Sharma, Yashoda, Anderson, Carl A., Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N., Andersen, Vibeke, Andrews, Jane M., Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A., Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R., Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H., Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C., Lees, Charlie W., Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R., Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y., Potocnik, Uros, Prescott, Natalie J., Rotter, Jerome I., Sanderson, Jeremy D., Sans, Miquel, Schreiber, Stefan, Simms, Lisa A., Sventoraityte, Jurgita, Targan, Stephan R., Taylor, Kent D., Tremelling, Mark, Verspaget, Hein W., De Vos, Martine, Wijmenga, Cisca, Wilson, David C., Winkelmann, Juliane, Xavier, Ramnik J., Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K., Zhao, Hongyu, Silverberg, Mark S., Annese, Vito, Hakonarson, Hakon, Brant, Steven R., Radford-Smith, Graham, Mathew, Christopher G., Rioux, John D., Schadt, Eric E., Daly, Mark J., Franke, Andre, Parkes, Miles, Vermeire, Severine, Barrett, Jeffrey C., Cho, Judy H

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Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data by Romagnoni, Alberto, Jégou, Simon, Van Steen, Kristel, Wainrib, Gilles, Hugot, Jean-Pierre

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