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Synthesis of New Congeners of 1-methyl-3-aminoisoquinolines, Evaluation of Their Cytotoxic Activity, In Silico and In Vitro Study of Their Molecular Targets as PDE4B
by
Lapa, Gennady B.
,
Tsunoda, Toshiyuki
,
Shirasawa, Senji
,
Baryshnikova, Maria A.
,
Evseev, Gregory G.
,
Afanasyeva, Daria A.
,
Chigorina, Elena A.
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Chemical biology & drug design
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Chemical Biology & Drug Design
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Subjects
3-Amino-Isoquinoline
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3D Floating Culture
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3‐Amino‐Isoquinoline
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Biochemistry & Molecular Biology
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Breast Cancer
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Cell Line, Tumor
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Chemistry, Medicinal
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Chromatography, Liquid
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Colorectal Cancer
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Computer Simulation
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Cytotoxic Activity
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Drug Screening Assays, Antitumor
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Hct116
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Hke3
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Humans
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In Vitro Techniques
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Isoquinolines - Chemical Synthesis
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Isoquinolines - Chemistry
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Isoquinolines - Pharmacology
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K562
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Wiley-Blackwell Journals
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