H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis by Harutyunyan, Ashot S., Krug, Brian, Chen, Haifen, Papillon-Cavanagh, Simon, Zeinieh, Michele, De Jay, Nicolas, Deshmukh, Shriya, Chen, Carol C. L., Belle, Jad, Mikael, Leonie G., Marchione, Dylan M., Li, Rui, Nikbakht, Hamid, Hu, Bo, Cagnone, Gael, Cheung, Warren A., Mohammadnia, Abdulshakour, Bechet, Denise, Faury, Damien, McConechy, Melissa K, Pathania, Manav, Jain, Siddhant U., Ellezam, Benjamin, Weil, Alexander G., Montpetit, Alexandre, Salomoni, Paolo, Pastinen, Tomi, Lu, Chao, Lewis, Peter W., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Majewski, Jacek

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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas by Khuong-Quang, Dong-Anh, Buczkowicz, Pawel, Rakopoulos, Patricia, Liu, Xiao-Yang, Fontebasso, Adam M., Bouffet, Eric, Bartels, Ute, Albrecht, Steffen, Schwartzentruber, Jeremy, Letourneau, Louis, Bourgey, Mathieu, Bourque, Guillaume, Montpetit, Alexandre, Bourret, Genevieve, Lepage, Pierre, Fleming, Adam, Lichter, Peter, Kool, Marcel, von Deimling, Andreas, Sturm, Dominik, Korshunov, Andrey, Faury, Damien, Jones, David T., Majewski, Jacek, Pfister, Stefan M., Jabado, Nada, Hawkins, Cynthia

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Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma by Nikbakht, Hamid, Panditharatna, Eshini, Mikael, Leonie G., Li, Rui, Gayden, Tenzin, Osmond, Matthew, Ho, Cheng-Ying, Kambhampati, Madhuri, Hwang, Eugene I., Faury, Damien, Siu, Alan, Papillon-Cavanagh, Simon, Bechet, Denise, Ligon, Keith L., Ellezam, Benjamin, Ingram, Wendy J., Stinson, Caedyn, Moore, Andrew S., Warren, Katherine E., Karamchandani, Jason, Packer, Roger J., Jabado, Nada, Majewski, Jacek, Nazarian, Javad

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Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas by Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, Sima, Koncar, Robert F., Agnihotri, Sameer, Faury, Damien, Ellezam, Benjamin, Weil, Alexander G., Ursini-Siegel, Josie, De Carvalho, Daniel D., Dirks, Peter B., Lewis, Peter W., Salomoni, Paolo, Lupien, Mathieu, Arrowsmith, Cheryl, Lasko, Paul F., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Mack, Stephen C.

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Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations by Liu, Xiao-Yang, Gerges, Noha, Korshunov, Andrey, Sabha, Nesrin, Khuong-Quang, Dong-Anh, Fontebasso, Adam M., Fleming, Adam, Hadjadj, Djihad, Schwartzentruber, Jeremy, Majewski, Jacek, Dong, Zhifeng, Siegel, Peter, Albrecht, Steffen, Croul, Sidney, Jones, David TW, Kool, Marcel, Tonjes, Martje, Reifenberger, Guido, Faury, Damien, Zadeh, Gelareh, Pfister, Stefan, Jabado, Nada

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Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas by Fontebasso, Adam M., Schwartzentruber, Jeremy, Khuong-Quang, Dong-Anh, Liu, Xiao-Yang, Sturm, Dominik, Korshunov, Andrey, Jones, David T. W., Witt, Hendrik, Kool, Marcel, Albrecht, Steffen, Fleming, Adam, Hadjadj, Djihad, Busche, Stephan, Lepage, Pierre, Montpetit, Alexandre, Staffa, Alfredo, Gerges, Noha, Zakrzewska, Magdalena, Zakrzewski, Krzystof, Liberski, Pawel P., Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Zadeh, Gelareh, Faury, Damien, Pfister, Stefan M., Jabado, Nada, Majewski, Jacek

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H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone by Khazaei, Sima, De Jay, Nicolas, Deshmukh, Shriya, Hendrikse, Liam D, Jawhar, Wajih, Chen, Carol C L, Mikael, Leonie G, Faury, Damien, Marchione, Dylan M, Lanoix, Joel, Bonneil, Éric, Ishii, Takeaki, Jain, Siddhant U, Rossokhata, Kateryna, Sihota, Tianna S, Eveleigh, Robert, Lisi, Véronique, Harutyunyan, Ashot S, Jung, Sungmi, Karamchandani, Jason, Dickson, Brendan C, Turcotte, Robert, Wunder, Jay S, Thibault, Pierre, Lewis, Peter W, Garcia, Benjamin A, Mack, Stephen C, Taylor, Michael D, Garzia, Livia, Kleinman, Claudia L, Jabado, Nada

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Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas by Bechet, Denise, Gielen, Gerrit G. H., Korshunov, Andrey, Pfister, Stefan M., Rousso, Caterina, Faury, Damien, Fiset, Pierre-Olivier, Benlimane, Naciba, Lewis, Peter W., Lu, Chao, David Allis, C., Kieran, Mark W., Ligon, Keith L., Pietsch, Torsten, Ellezam, Benjamin, Albrecht, Steffen, Jabado, Nada

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Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function by Andrade, Augusto Faria, Annett, Alva, Karimi, Elham, Topouza, Danai Georgia, Rezanejad, Morteza, Liu, Yitong, McNicholas, Michael, Gonzalez Santiago, Eduardo G., Llivichuzhca-Loja, Dhana, Gehlhaar, Arne, Jessa, Selin, De Cola, Antonella, Chandarana, Bhavyaa, Russo, Caterina, Faury, Damien, Danieau, Geoffroy, Puligandla, Evan, Wei, Yuhong, Zeinieh, Michele, Wu, Qing, Hebert, Steven, Juretic, Nikoleta, Nakada, Emily M., Krug, Brian, Larouche, Valerie, Weil, Alexander G., Dudley, Roy W. R., Karamchandani, Jason, Agnihotri, Sameer, Quail, Daniela F., Ellezam, Benjamin, Konnikova, Liza, Walsh, Logan A., Pathania, Manav, Kleinman, Claudia L., Jabado, Nada

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Detection and genomic analysis of BRAF fusions in Juvenile Pilocytic Astrocytoma through the combination and integration of multi-omic data by Zwaig, Melissa, Baguette, Audrey, Hu, Bo, Johnston, Michael, Lakkis, Hussein, Nakada, Emily M, Faury, Damien, Juretic, Nikoleta, Ellezam, Benjamin, Weil, Alexandre G, Karamchandani, Jason, Majewski, Jacek, Blanchette, Mathieu, Taylor, Michael D, Gallo, Marco, Kleinman, Claudia L, Jabado, Nada, Ragoussis, Jiannis

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Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas by JACOB, Karine, QUANG-KHUONG, Dongh-Anh, GARAMI, Miklos, HAUSER, Peter, KLEKNER, Almos, BOGNAR, Laszlo, FARMER, Jean-Pierre, MONTES, Jose-Luis, ATKINSON, Jeffrey, HAWKINS, Cynthia, KORSHUNOV, Andrey, COLLINS, V. Peter, JONES, David T. W, PFISTER, Stefan M, TABORI, Uri, JABADO, Nada, WITT, Hendrik, LAMBERT, Sally, ALBRECHT, Steffen, WITT, Olaf, VEZINA, Catherine, SHIRINIAN, Margret, FAURY, Damien

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Management of Inoperable Supra-Sellar Low-Grade Glioma With BRAF Mutation in Young Children by Howden, Kaitlyn, Chapman, Stacy, Serletis, Demitre, Kazina, Colin, Rafay, Mubeen F, Faury, Damien, Hazrati, Lili-Naz, Jabado, Nada, Vanan, Magimairajan Issai

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Gene Expression Profiling from Formalin-Fixed Paraffin-Embedded Tumors of Pediatric Glioblastoma by HAQUE, Takrima, FAURY, Damien, NANTEL, Andre, JABADO, Nada, ALBRECHT, Steffen, LOPEZ-AGUILAR, Enrique, HAUSER, Peter, GARAMI, Miklos, HANZELY, Zoltan, BOGNAR, Laszlo, DEL MAESTRO, Rolando F, ATKINSON, Jeffrey

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Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma by Sturm, Dominik, Witt, Hendrik, Hovestadt, Volker, Khuong-Quang, Dong-Anh, Jones, David T.W., Konermann, Carolin, Pfaff, Elke, Tönjes, Martje, Sill, Martin, Bender, Sebastian, Kool, Marcel, Zapatka, Marc, Becker, Natalia, Zucknick, Manuela, Hielscher, Thomas, Liu, Xiao-Yang, Fontebasso, Adam M., Ryzhova, Marina, Albrecht, Steffen, Jacob, Karine, Wolter, Marietta, Ebinger, Martin, Schuhmann, Martin U., van Meter, Timothy, Frühwald, Michael C., Hauch, Holger, Pekrun, Arnulf, Radlwimmer, Bernhard, Niehues, Tim, von Komorowski, Gregor, Dürken, Matthias, Kulozik, Andreas E., Madden, Jenny, Donson, Andrew, Foreman, Nicholas K., Drissi, Rachid, Fouladi, Maryam, Scheurlen, Wolfram, von Deimling, Andreas, Monoranu, Camelia, Roggendorf, Wolfgang, Herold-Mende, Christel, Unterberg, Andreas, Kramm, Christof M., Felsberg, Jörg, Hartmann, Christian, Wiestler, Benedikt, Wick, Wolfgang, Milde, Till, Witt, Olaf, Lindroth, Anders M., Schwartzentruber, Jeremy, Faury, Damien, Fleming, Adam, Zakrzewska, Magdalena, Liberski, Pawel P., Zakrzewski, Krzysztof, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Morrissy, Sorana, Cavalli, Florence, Taylor, Michael D., van Sluis, Peter, Koster, Jan, Versteeg, Rogier, Volckmann, Richard, Mikkelsen, Tom, Aldape, Kenneth, Reifenberger, Guido, Collins, V. Peter, Majewski, Jacek, Korshunov, Andrey, Lichter, Peter, Plass, Christoph, Jabado, Nada, Pfister, Stefan M.

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Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis by Chen, Carol C.L., Deshmukh, Shriya, Jessa, Selin, Hadjadj, Djihad, Lisi, Véronique, Andrade, Augusto Faria, Faury, Damien, Jawhar, Wajih, Dali, Rola, Suzuki, Hiromichi, Pathania, Manav, A, Deli, Dubois, Frank, Woodward, Eleanor, Hébert, Steven, Coutelier, Marie, Karamchandani, Jason, Albrecht, Steffen, Brandner, Sebastian, De Jay, Nicolas, Gayden, Tenzin, Bajic, Andrea, Harutyunyan, Ashot S., Marchione, Dylan M., Mikael, Leonie G., Juretic, Nikoleta, Zeinieh, Michele, Russo, Caterina, Maestro, Nicola, Bassenden, Angelia V., Hauser, Peter, Virga, József, Bognar, Laszlo, Klekner, Almos, Zapotocky, Michal, Vicha, Ales, Krskova, Lenka, Vanova, Katerina, Zamecnik, Josef, Sumerauer, David, Ekert, Paul G., Ziegler, David S., Ellezam, Benjamin, Filbin, Mariella G., Blanchette, Mathieu, Hansford, Jordan R., Khuong-Quang, Dong-Anh, Berghuis, Albert M., Weil, Alexander G., Garcia, Benjamin A., Garzia, Livia, Mack, Stephen C., Beroukhim, Rameen, Ligon, Keith L., Taylor, Michael D., Bandopadhayay, Pratiti, Kramm, Christoph, Pfister, Stefan M., Korshunov, Andrey, Sturm, Dominik, Jones, David T.W., Salomoni, Paolo, Kleinman, Claudia L., Jabado, Nada

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma by Schwartzentruber, Jeremy, Korshunov, Andrey, Liu, Xiao-Yang, Jones, David T. W., Pfaff, Elke, Jacob, Karine, Sturm, Dominik, Fontebasso, Adam M., Quang, Dong-Anh Khuong, Tönjes, Martje, Hovestadt, Volker, Albrecht, Steffen, Kool, Marcel, Nantel, Andre, Konermann, Carolin, Lindroth, Anders, Jäger, Natalie, Rausch, Tobias, Ryzhova, Marina, Korbel, Jan O., Hielscher, Thomas, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Ebinger, Martin, Schuhmann, Martin U., Scheurlen, Wolfram, Pekrun, Arnulf, Frühwald, Michael C., Roggendorf, Wolfgang, Kramm, Christoph, Dürken, Matthias, Atkinson, Jeffrey, Lepage, Pierre, Montpetit, Alexandre, Zakrzewska, Magdalena, Zakrzewski, Krzystof, Liberski, Pawel P., Dong, Zhifeng, Siegel, Peter, Kulozik, Andreas E., Zapatka, Marc, Guha, Abhijit, Malkin, David, Felsberg, Jörg, Reifenberger, Guido, von Deimling, Andreas, Ichimura, Koichi, Collins, V. Peter, Witt, Hendrik, Milde, Till, Witt, Olaf, Zhang, Cindy, Castelo-Branco, Pedro, Lichter, Peter, Faury, Damien, Tabori, Uri, Plass, Christoph, Majewski, Jacek, Pfister, Stefan M., Jabado, Nada

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Acquired Omenn-Like Syndrome, a Novel Posttransplant Autoaggression Syndrome Reversed by Rapamycin by Vinh, Donald C, Bin Dhuban, Khalid, Mason, Helen, Lejtenyi, Duncan, Jung, Sungmi, Sheppard, Donald C, Faury, Damien, Jabado, Nada, Piccirillo, Ciriaco A

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Single Cell Transcriptomic Analysis of the Histone H3 K27M Mutation in Pre-Leukemic Hematopoietic Stem Cells by Boileau, Meaghan, Jessa, Selin, Worme, Samantha, Faury, Damien, Jabado, Nada, Mercier, François, Kleinman, Claudia, Eppert, Kolja

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A Compendium of Syngeneic, Transplantable Pediatric High-Grade Glioma Models Reveals Subtype-Specific Therapeutic Vulnerabilities by McNicholas, Michael, De Cola, Antonella, Bashardanesh, Zahedeh, Foss, Amelia, Lloyd, Cameron B, Hébert, Steven, Faury, Damien, Andrade, Augusto Faria, Jabado, Nada, Kleinman, Claudia L, Pathania, Manav

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MODL-08. A COMPENDIUM OF SYNGENEIC, TRANSPLANTABLE PEDIATRIC HIGH-GRADE GLIOMA MODELS REVEALS SUBTYPE-SPECIFIC THERAPEUTIC VULNERABILITIES by McNicholas, Michael, De Cola, Antonella, Bashardanesh, Zahedeh, Foss, Amelia, Lloyd, Cameron, Hebert, Steven, Faury, Damien, Andrade, Augusto Faria, Jabado, Nada, Kleinman, Claudia, Pathania, Manav

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