Brain and visceral gene editing of mucopolysaccharidosis I mice by nasal delivery of the CRISPR/Cas9 system by Vera, Luisa Natalia Pimentel, Schuh, Roselena Silvestri, Fachel, Flavia Nathielly Silveira, Poletto, Edina, Piovesan, Eduarda, Kubaski, Francyne, Couto, Eduarda, Brum, Bruna, Rodrigues, Graziella, Souza, Hallana, Giugliani, Roberto, Matte, Ursula, Baldo, Guilherme, Teixeira, Helder F.

Get full text

Box-Behnken design optimization of mucoadhesive chitosan-coated nanoemulsions for rosmarinic acid nasal delivery—In vitro studies by Fachel, Flávia Nathiely Silveira, Medeiros-Neves, Bruna, Dal Prá, Morgana, Schuh, Roselena Silvestri, Veras, Kleyton Santos, Bassani, Valquíria Linck, Koester, Letícia Scherer, Henriques, Amelia Teresinha, Braganhol, Elizandra, Teixeira, Helder Ferreira

Get full text

An overview of the neuroprotective potential of rosmarinic acid and its association with nanotechnology-based delivery systems: A novel approach to treating neurodegenerative disor... by Fachel, Flávia Nathiely Silveira, Schuh, Roselena Silvestri, Veras, Kleyton Santos, Bassani, Valquíria Linck, Koester, Letícia Scherer, Henriques, Amelia Teresinha, Braganhol, Elizandra, Teixeira, Helder Ferreira

Get full text

Metastatic Melanoma: A Preclinical Model Standardization and Development of a Chitosan-Coated Nanoemulsion Containing Temozolomide to Treat Brain Metastasis by Gelsleichter, Nicolly Espindola, de Souza, Priscila Oliveira, Teixeira, Fernanda Cardoso, Debom, Gabriela Nogueira, Lenz, Gabriela Spies, Roliano, Gabriela Gonçalves, de Cássia Sant’ana, Rita, Visioli, Fernanda, Fachel, Flávia Nathiely Silveira, Michels, Luana Roberta, Azambuja, Juliana Hofstätter, Teixeira, Helder Ferreira, Braganhol, Elizandra

Get full text

Technological strategies applied for rosmarinic acid delivery through different routes – A review by Veras, Kleyton S., Fachel, Flávia Nathiely S., Teixeira, Helder F., Koester, Letícia S.

Get full text

Complexation of rosmarinic acid with hydroxypropyl-β-cyclodextrin and methyl-β-cyclodextrin: Formation of 2:1 complexes with improved antioxidant activity by Veras, Kleyton Santos, Silveira Fachel, Flávia Nathiely, Delagustin, Maria Gabriele, Teixeira, Helder Ferreira, Barcellos, Thiago, Henriques, Amélia Teresinha, Bassani, Valquíria Linck, Koester, Letícia Scherer

Get full text

Soybeans isoflavone aglycone-rich extracts: Optimization by different bioprocesses and production of a purified fraction with promising wound healing property by Nemitz, Marina Cardoso, Fachel, Flávia Nathiely Silveira, Beckenkamp, Aline, Buffon, Andréia, Teixeira, Helder Ferreira, Poser, Gilsane Lino von

Get full text

Chitosan-coated rosmarinic acid nanoemulsion nasal administration protects against LPS-induced memory deficit, neuroinflammation, and oxidative stress in Wistar rats by Fachel, Flávia Nathiely Silveira, Michels, Luana Roberta, Azambuja, Juliana Hofstätter, Lenz, Gabriela Spies, Gelsleichter, Nicolly Espindola, Endres, Marcelo, Scholl, Juliete Nathali, Schuh, Roselena Silvestri, Barschak, Alethea Gatto, Figueiró, Fabrício, Bassani, Valquíria Linck, Henriques, Amelia Teresinha, Koester, Letícia Scherer, Teixeira, Helder Ferreira, Braganhol, Elizandra

Get full text

Development, physico‐chemical characterization and in‐vitro studies of hydrogels containing rosmarinic acid‐loaded nanoemulsion for topical application by Marafon, Paula, Fachel, Flávia Nathiely Silveira, Dal Prá, Morgana, Bassani, Valquíria Linck, Koester, Letícia Scherer, Henriques, Amélia Teresinha, Braganhol, Elizandra, Teixeira, Helder Ferreira

Get full text

Hydrogels containing soybean isoflavone aglycones-rich fraction-loaded nanoemulsions for wound healing treatment – in vitro and in vivo studies by Back, Patricia Inês, Balestrin, Lucélia Albarello, Fachel, Flávia Nathiely Silveira, Nemitz, Marina Cardoso, Falkembach, Mariana, Soares, Gabriela, Marques, Magno da Silva, Silveira, Tony, Dal Prá, Morgana, Horn, Ana Paula, Braganhol, Elizandra, von Poser, Gilsane Lino, Dora, Cristiana Lima, Teixeira, Helder Ferreira

Get full text

Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review by Veras, Kleyton Santos, Fachel, Flávia Nathiely Silveira, de Araújo, Bibiana Verlindo, Teixeira, Helder Ferreira, Koester, Letícia Scherer

Get full text

Compatibility study of rosmarinic acid with excipients used in pharmaceutical solid dosage forms using thermal and non-thermal techniques by Veras, Kleyton Santos, Fachel, Flávia Nathiely Silveira, Pittol, Vanessa, Garcia, Keth Ribeiro, Bassani, Valquíria Linck, dos Santos, Venina, Henriques, Amélia Teresinha, Teixeira, Helder Ferreira, Koester, Letícia Scherer

Get full text

Topical Nanoemulsions as Delivery Systems for Green Extracts of Pterocaulon balansae Aiming at the Treatment of Sporotrichosis by Medeiros-Neves, Bruna, Heidrich, Daiane, Schuh, Roselena Silvestri, Brazil, Nathalya Tesch, Fachel, Flávia Nathiely Silveira, Cassel, Eduardo, Vargas, Rubem Mário Figueiró, Scroferneker, Maria Lúcia, von Poser, Gilsane Lino, Koester, Letícia Scherer, Teixeira, Helder Ferreira

Get full text

Effect of Hydrogel Containing Achyrocline satureioides (Asteraceae) Extract-Loaded Nanoemulsions on Wound Healing Activity by Balestrin, Lucélia Albarello, Back, Patrícia Inês, Marques, Magno da Silva, Araújo, Gabriela de Moraes Soares, Carrasco, Mariana Corrêa Falkembach, Batista, Matheus Monteiro, Silveira, Tony, Rodrigues, Jamile Lima, Fachel, Flávia Nathiely Silveira, Koester, Leticia Scherer, Bassani, Valquiria Linck, Horn, Ana Paula, Dora, Cristiana Lima, Teixeira, Helder Ferreira

Get full text

Physicochemical properties of cationic nanoemulsions and liposomes obtained by microfluidization complexed with a single plasmid or along with an oligonucleotide: Implications for... by Schuh, Roselena S., Poletto, Édina, Fachel, Flávia N.S., Matte, Ursula, Baldo, Guilherme, Teixeira, Helder F.

Get full text

The proteomic and particle composition of human platelet lysate for cell therapy products by Rodrigues, Raul M., Valim, Vanessa de Souza, Berger, Markus, Silva, Annelise P. M., Fachel, Flávia N. S., Wilke, Ianaê I., Silva, Walter O. B., Santi, Lucélia, Silva, Maria A. L., Amorin, Bruna, Sehn, Filipe, Yates, John R., Guimarães, Jorge A., Silla, Lucia

Get full text

Curcumin and Quercetin-Loaded Lipid Nanocarriers: Development of Omega-3 Mucoadhesive Nanoemulsions for Intranasal Administration by Vaz, Gustavo Richter, Carrasco, Mariana Corrêa Falkembach, Batista, Matheus Monteiro, Barros, Paula Alice Bezerra, Oliveira, Meliza da Conceição, Muccillo-Baisch, Ana Luiza, Yurgel, Virginia Campello, Buttini, Francesca, Soares, Félix Alexandre Antunes, Cordeiro, Larissa Marafiga, Fachel, Flavia, Teixeira, Helder Ferreira, Bidone, Juliana, de Oliveira, Patrícia Diaz, Sonvico, Fabio, Dora, Cristiana Lima

Get full text

Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses by Fachel, Flávia Nathiely Silveira, Frâncio, Lariane, Poletto, Édina, Schuh, Roselena Silvestri, Teixeira, Helder Ferreira, Giugliani, Roberto, Baldo, Guilherme, Matte, Ursula

Get full text

Nasal administration of a temozolomide-loaded thermoresponsive nanoemulsion reduces tumor growth in a preclinical glioblastoma model by Michels, Luana Roberta, Fachel, Flávia Nathiely Silveira, Schuh, Roselena Silvestri, Azambuja, Juliana Hofstätter, de Souza, Priscila Oliveira, Gelsleichter, Nicolly Espindola, Lenz, Gabriela Spies, Visioli, Fernanda, Braganhol, Elizandra, Teixeira, Helder Ferreira

Get full text

A novel, simplified and stability-indicating high-throughput ultra-fast liquid chromatography method for the determination of rosmarinic acid in nanoemulsions, porcine skin and nas... by Fachel, Flávia N.S., Nemitz, Marina C., Medeiros-Neves, Bruna, Veras, Kleyton S., Bassani, Valquíria L., Koester, Letícia S., Henriques, Amelia T., Teixeira, Helder F.

Get full text