A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction by Somers, Klaartje, Wen, Victoria W., Middlemiss, Shiloh M. C., Osborne, Brenna, Forgham, Helen, Jung, MoonSun, Karsa, Mawar, Clifton, Molly, Bongers, Angelika, Gao, Jixuan, Mayoh, Chelsea, Raoufi-Rad, Newsha, Kusnadi, Eric P., Hannan, Kate M., Scott, David A., Kwek, Alan, Liu, Bing, Flemming, Claudia, Chudakova, Daria A., Pandher, Ruby, Failes, Tim W., Lim, James, Angeli, Andrea, Osterman, Andrei L., Imamura, Toshihiko, Kees, Ursula R., Supuran, Claudiu T., Pearson, Richard B., Hannan, Ross D., Davis, Thomas P., McCarroll, Joshua, Kavallaris, Maria, Turner, Nigel, Gudkov, Andrei V., Haber, Michelle, Norris, Murray D., Henderson, Michelle J.

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Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen by Cheung, Leanna, Yu, Denise M.T., Neiron, Zillan, Failes, Tim W., Arndt, Greg M., Fletcher, Jamie I.

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FDA-approved disulfiram as a novel treatment for aggressive leukemia by Karsa, Mawar, Xiao, Lin, Ronca, Emma, Bongers, Angelika, Spurling, Dayna, Karsa, Ayu, Cantilena, Sandra, Mariana, Anna, Failes, Tim W., Arndt, Greg M., Cheung, Laurence C., Kotecha, Rishi S., Sutton, Rosemary, Lock, Richard B., Williams, Owen, de Boer, Jasper, Haber, Michelle, Norris, Murray D., Henderson, Michelle J., Somers, Klaartje

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Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms by Ariey-Bonnet, Jérémy, Berges, Raphael, Montero, Marie-Pierre, Mouysset, Baptiste, Piris, Patricia, Muller, Kevin, Pinna, Guillaume, Failes, Tim W., Arndt, Greg M., Morando, Philippe, Baeza-Kallee, Nathalie, Colin, Carole, Chinot, Olivier, Braguer, Diane, Morelli, Xavier, André, Nicolas, Carré, Manon, Tabouret, Emeline, Figarella-Branger, Dominique, Le Grand, Marion, Pasquier, Eddy

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Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and... by Thoms, Julie A.I., Schnegg-Kaufmann, Annatina, Bhuyan, Golam Sarower, Hampton, Henry R., Vaughan, Lachlin, Rutherford, Kayleigh, Kakadia, Purvi M., Lee, Hui Mei, Johansson, Emma, Failes, Tim W., Arndt, Greg M., Koval, Jason, Davidson, Sarah, Lindeman, Robert, Warburton, Pauline, Rodriguez-Meira, Alba, Mead, Adam J, Unnikrishnan, Ashwin, Hertzberg, Mark, Polizzotto, Mark N., Papaemmanuil, Elli, Bohlander, Stefan K., Faridani, Omid, Jolly, Christopher J., Zanini, Fabio, Pimanda, John E.

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Abstract 4037: High throughput kinase inhibitor screen reveals novel inhibitor combinations acting in synergy with TUBB3 /βIII-tubulin suppression in non-small cell lung cancer by Teo, Wee Siang, Dwarte, Tanya, Failes, Tim W., Arndt, Greg M., McCarroll, Joshua A., Kavallaris, Maria

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In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer by Lau, Loretta M S, Mayoh, Chelsea, Xie, Jinhan, Barahona, Paulette, MacKenzie, Karen L, Wong, Marie, Kamili, Alvin, Tsoli, Maria, Failes, Tim W, Kumar, Amit, Mould, Emily V A, Gifford, Andrew, Chow, Shu‐Oi, Pinese, Mark, Fletcher, Jamie I, Arndt, Greg M, Khuong‐Quang, Dong‐Anh, Wadham, Carol, Batey, Daniel, Eden, Georgina, Trebilcock, Peter, Joshi, Swapna, Alfred, Stephanie, Gopalakrishnan, Anjana, Khan, Aaminah, Grebert Wade, Dylan, Strong, Patrick A, Manouvrier, Elodie, Morgan, Lisa T, Span, Miriam, Lim, Jin Yi, Cadiz, Roxanne, Ung, Caitlin, Thomas, David M, Tucker, Katherine M, Warby, Meera, McCowage, Geoffrey B, Dalla‐Pozza, Luciano, Byrne, Jennifer A, Saletta, Federica, Fellowes, Andrew, Fox, Stephen B, Norris, Murray D, Tyrrell, Vanessa, Trahair, Toby N, Lock, Richard B, Cowley, Mark J, Ekert, Paul G, Haber, Michelle, Ziegler, David S, Marshall, Glenn M

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Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergismsResearch in context by Jérémy Ariey-Bonnet, Raphael Berges, Marie-Pierre Montero, Baptiste Mouysset, Patricia Piris, Kevin Muller, Guillaume Pinna, Tim W. Failes, Greg M. Arndt, Philippe Morando, Nathalie Baeza-Kallee, Carole Colin, Olivier Chinot, Diane Braguer, Xavier Morelli, Nicolas André, Manon Carré, Emeline Tabouret, Dominique Figarella-Branger, Marion Le Grand, Eddy Pasquier

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Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms by Ariey-Bonnet, Jérémy, Berges, Raphael, Montero, Marie-Pierre, Mouysset, Baptiste, Piris, Patricia, Muller, Kevin, Pinna, Guillaume, Failes, Tim W, Arndt, Greg M, Morando, Philippe, Baeza-Kallee, Nathalie, Colin, Carole, Chinot, Olivier, Braguer, Diane, Morelli, Xavier, André, Nicolas, Carré, Manon, Tabouret, Emeline, Figarella-Branger, Dominique, Le Grand, Marion, Pasquier, Eddy Eddy

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Combination efficacy of ruxolitinib with standard-of-care drugs in CRLF2-rearranged Ph-like acute lymphoblastic leukemia by Bӧhm, Julia W., Sia, Keith C. S., Jones, Connor, Evans, Kathryn, Mariana, Anna, Pang, Ignatius, Failes, Tim, Zhong, Ling, Mayoh, Chelsea, Landman, Robert, Collins, Robert, Erickson, Stephen W., Arndt, Greg, Raftery, Mark J., Wilkins, Marc R., Norris, Murray D., Haber, Michelle, Marshall, Glenn M., Lock, Richard B.

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