Diversity Oriented Routes to Thiopeptide Antibiotics: A Solution to the "Thiazole Problem" by Ferguson, Mai Lam, Ciufolini, Marco A

Get full text

Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia by Zhang, Lu, Cai, Tianyu, Lin, Xiaoyu, Huang, Xiaoli, Bui, Mai H, Plotnik, Joshua P, Bellin, Richard J, Faivre, Emily J, Kuruvilla, Vinitha M, Lam, Lloyd T, Lu, Xin, Zha, Zheng, Feng, Weiguo, Hessler, Paul, Uziel, Tamar, Zhang, Qi, Cavazos, Antonio, Han, Lina, Ferguson, Debra C, Mehta, Gaurav, Shanmugavelandy, Sriram S, Magoc, Terrance J, Rowe, Jenny, Goodwin, Neal C, Dorritie, Kathleen A, Boyiadzis, Michael, Albert, Daniel H, McDaniel, Keith F, Kati, Warren M, Konopleva, Marina, Shen, Yu

Get full text

Abstract 800: ABBV-744, a first-in-class and highly selective inhibitor of the second bromodomain of BET family proteins, displays robust activities in preclinical models of acute... by Lin, Xiaoyu, Huang, Xiaoli, Bellin, Richard, Faivre, Emily, Hessler, Paul, Lam, Lloyd, Bui, Mai Ha, Wilcox, Denise, Uziel, Tamar, Ferguson, Debra C., Magoc, Terrance J., Albert, Daniel H., McDaniel, Keith F., Kati, Warren, Shen, Yu

Get full text