Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors by Frampton, Garrett M, Ali, Siraj M, Rosenzweig, Mark, Chmielecki, Juliann, Lu, Xinyuan, Bauer, Todd M, Akimov, Mikhail, Bufill, Jose A, Lee, Carrie, Jentz, David, Hoover, Rick, Ou, Sai-Hong Ignatius, Salgia, Ravi, Brennan, Tim, Chalmers, Zachary R, Jaeger, Savina, Huang, Alan, Elvin, Julia A, Erlich, Rachel, Fichtenholtz, Alex, Gowen, Kyle A, Greenbowe, Joel, Johnson, Adrienne, Khaira, Depinder, McMahon, Caitlin, Sanford, Eric M, Roels, Steven, White, Jared, Greshock, Joel, Schlegel, Robert, Lipson, Doron, Yelensky, Roman, Morosini, Deborah, Ross, Jeffrey S, Collisson, Eric, Peters, Malte, Stephens, Philip J, Miller, Vincent A

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Methotrexate-Immobilized Poly(ethylene glycol) Magnetic Nanoparticles for MR Imaging and Drug Delivery by Kohler, Nathan, Sun, Conroy, Fichtenholtz, Alex, Gunn, Jonathan, Fang, Chen, Zhang, Miqin

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Abstract 1118: Activation of MET via diverse exon 14 skipping mutations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors by Frampton, Garrett M., Ali, Siraj, Chmielecki, Juliann, Rosenzweig, Mark, Brennan, Timothy, Chalmers, Zachary, Elvin, Julia, Fichtenholtz, Alex, Gowan, Kyle, Greenbowe, Joel, Johnson, Adrienne, Khaira, Lily, Lipson, Doron, McMahon, Caitlin, Roels, Steven, Yelensky, Roman, Morosini, Deborah, Stephens, Philip, Miller, Vincent

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Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing by Frampton, Garrett M, Fichtenholtz, Alex, Otto, Geoff A, Wang, Kai, Downing, Sean R, He, Jie, Schnall-Levin, Michael, White, Jared, Sanford, Eric M, An, Peter, Sun, James, Juhn, Frank, Brennan, Kristina, Iwanik, Kiel, Maillet, Ashley, Buell, Jamie, White, Emily, Zhao, Mandy, Balasubramanian, Sohail, Terzic, Selmira, Richards, Tina, Banning, Vera, Garcia, Lazaro, Mahoney, Kristen, Zwirko, Zac, Donahue, Amy, Beltran, Himisha, Mosquera, Juan Miguel, Rubin, Mark A, Dogan, Snjezana, Hedvat, Cyrus V, Berger, Michael F, Pusztai, Lajos, Lechner, Matthias, Boshoff, Chris, Jarosz, Mirna, Vietz, Christine, Parker, Alex, Miller, Vincent A, Ross, Jeffrey S, Curran, John, Cronin, Maureen T, Stephens, Philip J, Lipson, Doron, Yelensky, Roman

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Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting by He, Jie, Abdel-Wahab, Omar, Nahas, Michelle K., Wang, Kai, Rampal, Raajit K., Intlekofer, Andrew M., Patel, Jay, Krivstov, Andrei, Frampton, Garrett M., Young, Lauren E., Zhong, Shan, Bailey, Mark, White, Jared R., Roels, Steven, Deffenbaugh, Jason, Fichtenholtz, Alex, Brennan, Timothy, Rosenzweig, Mark, Pelak, Kimberly, Knapp, Kristina M., Brennan, Kristina W., Donahue, Amy L., Young, Geneva, Garcia, Lazaro, Beckstrom, Selmira T., Zhao, Mandy, White, Emily, Banning, Vera, Buell, Jamie, Iwanik, Kiel, Ross, Jeffrey S., Morosini, Deborah, Younes, Anas, Hanash, Alan M., Paietta, Elisabeth, Roberts, Kathryn, Mullighan, Charles, Dogan, Ahmet, Armstrong, Scott A., Mughal, Tariq, Vergilio, Jo-Anne, Labrecque, Elaine, Erlich, Rachel, Vietz, Christine, Yelensky, Roman, Stephens, Philip J., Miller, Vincent A., van den Brink, Marcel R.M., Otto, Geoff A., Lipson, Doron, Levine, Ross L.

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Abstract LB-328: Subtypes of urothelial carcinoma of the urinary bladder defined by genomic alteration combinations predict clinical characteristics by Khan, Alyna, Fichtenholtz, Alex, Ross, Jeffrey, Frampton, Garrett, Neumann, Eric, Ali, Siraj M., Stephens, Phil J.

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Abstract 4667: The complex genomic landscape of glial tumors reveals distinct subclasses and potential therapeutic targets associated with clinical responses to targeted inhibitors by Chmielecki, Juliann, Goldberg, Michael E., Fichtenholtz, Alex, Elvin, Julia, Frampton, Garrett M., Ali, Siraj M., Ross, Jeffrey S., Morosini, Deborah, Miller, Vincent A., Piccioni, David, Kesari, Santosh, Stephens, Philip J.

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Abstract 3570: Development and validation of a clinical next generation sequencing-based assay for hematologic malignancies by Lipson, Doron, Nahas, Michelle K., Otto, Geoff A., He, Jie, Wang, Kai, Knapp, Kristina M., Brennan, Kristina W., Donahue, Amy L., Young, Lauren E., Young, Geneva, Fichtenholtz, Alex, Ross, Jeffrey S., Yelensky, Roman, Stephens, Philip J., Miller, Vincent A., Levine, Ross

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Abstract 2279: Bringing next generation sequencing (NGS) to the clinic: Analytical validation of a comprehensive NGS-based cancer gene test by Yelensky, Roman, Frampton, Garrett M., Fichtenholtz, Alex, Downing, Sean, He, Jie, Juhn, Frank, Brennan, Kristina, Wang, Kai, Otto, Geoff, Jarosz, Mirna, Parker, Alex, Ross, Jeffrey S., Curran, John, Cronin, Maureen T., Stephens, Philip J., Lipson, Doron

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Identification Of Actionable Genomic Alterations In Hematologic Malignancies By a Clinical Next Generation Sequencing-Based Assay by Lipson, Doron, Nahas, Michelle K, Otto, Geoff A., Yelensky, Roman, Abdel-Wahab, Omar, Wang, Kai, He, Jie, Intlekofer, Andrew M., Rampal, Raajit K., Brennan, Timothy A, Knapp, Kristina M., Brennan, Kristina W, Young, Geneva, Donahue, Amy L, Sanford, Eric M, Greenbowe, Joel R, Frampton, Garrett M, Fichtenholtz, Alex, Young, Lauren E, Erlich, Rachel L, Parker, Alex, Klimstra, David, Dogan, Ahmet, Ross, Jeffrey S, Armstrong, Scott A., Stephens, Philip J., van den Brink, Marcel R.M., Miller, Vincent A., Levine, Ross L.

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