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Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors
by
Hanisak, Jennifer
,
Seganish, W. Michael
,
McElroy, William T.
,
Tang, Haiquin
,
Zhang, Rui
,
Tsui, Hon-Chung
,
Fischmann, Theirry
,
Tulshian, Deen
,
Tata, James
,
Sondey, Christopher
,
Devito, Kristine
,
Fossetta, James
,
Garlisi, Charles G.
,
Lundell, Daniel
,
Niu, Xiaoda
Published in
Bioorganic & medicinal chemistry letters
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Journal Title
Bioorganic & Medicinal Chemistry Letters
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Subjects
60 Applied Life Sciences
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Animals
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Binding Sites
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Chemistry
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Chemistry, Medicinal
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Chemistry, Organic
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Crystallography, X-Ray
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Half-Life
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Humans
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Inflammation
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Inorganic, Organic, Physical, And Analytical Chemistry
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Interleukin Receptor-Associated Kinases
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Interleukin-1 Receptor-Associated Kinases - Antagonists & Inhibitors
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Interleukin-1 Receptor-Associated Kinases - Metabolism
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Irak4
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Life Sciences & Biomedicine
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Ligands
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Molecular Dynamics Simulation
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Pharmacology & Pharmacy
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Physical Sciences
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Sciencedirect Journals
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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