Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment by Wiegman, Albert, Gidding, Samuel S, Watts, Gerald F, Chapman, M John, Ginsberg, Henry N, Cuchel, Marina, Ose, Leiv, Averna, Maurizio, Boileau, Catherine, Borén, Jan, Bruckert, Eric, Catapano, Alberico L, Defesche, Joep C, Descamps, Olivier S, Hegele, Robert A, Hovingh, G Kees, Humphries, Steve E, Kovanen, Petri T, Kuivenhoven, Jan Albert, Masana, Luis, Nordestgaard, Børge G, Pajukanta, Päivi, Parhofer, Klaus G, Raal, Frederick J, Ray, Kausik K, Santos, Raul D, Stalenhoef, Anton F H, Steinhagen-Thiessen, Elisabeth, Stroes, Erik S, Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Wiklund, Olov

Get full text

Effects of Supra-Physiological Levothyroxine Dosages on Liver Parameters, Lipids and Lipoproteins in Healthy Volunteers: A Randomized Controlled Crossover Study by Sjouke, Barbara, Elbers, Laura P. B., van Zaane, Bregje, Kastelein, John J. P., Hovingh, G. Kees, Gerdes, Victor E. A.

Get full text

Using genetic association data to guide drug discovery and development: Review of methods and applications by Burgess, Stephen, Mason, Amy M., Grant, Andrew J., Slob, Eric A.W., Gkatzionis, Apostolos, Zuber, Verena, Patel, Ashish, Tian, Haodong, Liu, Cunhao, Haynes, William G., Hovingh, G. Kees, Knudsen, Lotte Bjerre, Whittaker, John C., Gill, Dipender

Get full text

Inclisiran Durably Lowers Low-Density Lipoprotein Cholesterol and Proprotein Convertase Subtilisin/Kexin Type 9 Expression in Homozygous Familial Hypercholesterolemia: The ORION-2... by Hovingh, G. Kees, Lepor, Norman E., Kallend, David, Stoekenbroek, Robert M., Wijngaard, Peter L.J., Raal, Frederick J.

Get full text

Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans[S] by Singaraja, Roshni R., Tietjen, Ian, Hovingh, G. Kees, Franchini, Patrick L., Radomski, Chris, Wong, Kenny, vanHeek, Margaret, Stylianou, Ioannis M., Lin, Linus, Wang, Liangsu, Mitnaul, Lyndon, Hubbard, Brian, Winther, Michael, Mattice, Maryanne, Legendre, Annick, Sherrington, Robin, Kastelein, John J., Akinsanya, Karen, Plump, Andrew, Hayden, Michael R.

Get full text

Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease by Ference, Brian A, Bhatt, Deepak L, Catapano, Alberico L, Packard, Chris J, Graham, Ian, Kaptoge, Stephen, Ference, Thatcher B, Guo, Qi, Laufs, Ulrich, Ruff, Christian T, Cupido, Arjen, Hovingh, G. Kees, Danesh, John, Holmes, Michael V, Smith, George Davey, Ray, Kausik K, Nicholls, Stephen J, Sabatine, Marc S

Get full text

HDL does not influence the polarization of human monocytes toward an alternative phenotype by Colin, Sophie, Fanchon, Mélanie, Belloy, Loic, Bochem, Andrea E, Copin, Corinne, Derudas, Bruno, Stroes, Erik S.G, Hovingh, G. Kees, Kuivenhoven, Jan A, Dallinga-Thie, Geesje M, Staels, Bart, Chinetti-Gbaguidi, Giulia

Get full text

The interplay between inflammatory cytokines and cardiometabolic disease: bi-directional mendelian randomisation study by Karhunen, Ville, Gill, Dipender, Huang, Jian, Bouras, Emmanouil, Malik, Rainer, Ponsford, Mark J, Ahola-Olli, Ari, Papadopoulou, Areti, Palaniswamy, Saranya, Sebert, Sylvain, Wielscher, Matthias, Auvinen, Juha, Veijola, Juha, Herzig, Karl-Heinz, Timonen, Markku, Keinänen-Kiukaanniemi, Sirkka, Dichgans, Martin, Salmi, Marko, Jalkanen, Sirpa, Lehtimäki, Terho, Salomaa, Veikko, Raitakari, Olli, Jones, Simon A, Hovingh, G Kees, Tsilidis, Konstantinos K, Järvelin, Marjo-Riitta, Dehghan, Abbas

Get full text

The cholesterol content of the erythrocyte membrane is an important determinant of phosphatidylserine exposure by van Zwieten, Rob, Bochem, Andrea E., Hilarius, Petra M., van Bruggen, Robin, Bergkamp, Ferry, Hovingh, G. Kees, Verhoeven, Arthur J.

Get full text

Correction to: Assessment of the 1% of Patients with Consistent < 15% Reduction in Low-Density Lipoprotein Cholesterol: Pooled Analysis of 10 Phase 3 ODYSSEY Alirocumab Trials by Bays, Harold E., Rosenson, Robert S., Baccara-Dinet, Marie T., Louie, Michael J., Thompson, Desmond, Kees Hovingh, G.

Get full text

Prevalence and management of familial hypercholesterolaemia in coronary patients: An analysis of EUROASPIRE IV, a study of the European Society of Cardiology by De Backer, Guy, Besseling, Joost, Chapman, John, Hovingh, G.Kees, Kastelein, John J.P, Kotseva, Kornelia, Ray, Kausik, Reiner, Željko, Wood, David, De Bacquer, Dirk

Get full text

Semaglutide for cardiovascular event reduction in people with overweight or obesity: SELECT study baseline characteristics by Lingvay, Ildiko, Brown‐Frandsen, Kirstine, Colhoun, Helen M., Deanfield, John, Emerson, Scott S., Esbjerg, Sille, Hardt‐Lindberg, Søren, Hovingh, G. Kees, Kahn, Steven E., Kushner, Robert F., Lincoff, A. Michael, Marso, Steven P., Fries, Tea Monk, Plutzky, Jorge, Ryan, Donna H.

Get full text

Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness by van den Bogaard, Bas, Holleboom, Adriaan G, Duivenvoorden, Raphaël, Hutten, Barbara A, Kastelein, John J.P, Hovingh, G. Kees, Kuivenhoven, Jan Albert, Stroes, Erik S.G, van den Born, Bert-Jan H

Get full text

2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein convertase subtilisin/kexin type 9 inhibition in patients with atherosclerotic cardiovascular diseas... by Landmesser, Ulf, Chapman, M John, Stock, Jane K, Amarenco, Pierre, Belch, Jill J F, Borén, Jan, Farnier, Michel, Ference, Brian A, Gielen, Stephan, Graham, Ian, Grobbee, Diederick E, Hovingh, G Kees, Lüscher, Thomas F, Piepoli, Massimo F, Ray, Kausik K, Stroes, Erik S, Wiklund, Olov, Windecker, Stephan, Zamorano, Jose Luis, Pinto, Fausto, Tokgözoğlu, Lale, Bax, Jeroen J, Catapano, Alberico L

Get full text

Dissecting the IL‐6 pathway in cardiometabolic disease: A Mendelian randomization study on both IL6 and IL6R by Cupido, Arjen J., Asselbergs, Folkert W., Natarajan, Pradeep, Ridker, Paul M., Hovingh, G. Kees, Schmidt, A. Floriaan

Get full text

In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1[S] by Holleboom, Adriaan G., Jakulj, Lily, Franssen, Remco, Decaris, Julie, Vergeer, Menno, Koetsveld, Joris, Luchoomun, Jayraz, Glass, Alexander, Hellerstein, Marc K., Kastelein, John J.P., Hovingh, G. Kees, Kuivenhoven, Jan Albert, Groen, Albert K., Turner, Scott M., Stroes, Erik S.G.

Get full text

Cardiovascular disease risk associated with elevated lipoprotein(a) attenuates at low low-density lipoprotein cholesterol levels in a primary prevention setting by Verbeek, Rutger, Hoogeveen, Renate M, Langsted, Anne, Stiekema, Lotte C A, Verweij, Simone L, Hovingh, G Kees, Wareham, Nicholas J, Khaw, Kay-Tee, Boekholdt, S Matthijs, Nordestgaard, Børge G, Stroes, Erik S G

Get full text

Adverse effects of statin therapy: perception vs. the evidence – focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract by Mach, François, Ray, Kausik K, Wiklund, Olov, Corsini, Alberto, Catapano, Alberico L, Bruckert, Eric, De Backer, Guy, Hegele, Robert A, Hovingh, G Kees, Jacobson, Terry A, Krauss, Ronald M, Laufs, Ulrich, Leiter, Lawrence A, März, Winfried, Nordestgaard, Børge G, Raal, Frederick J, Roden, Michael, Santos, Raul D, Stein, Evan A, Stroes, Erik S, Thompson, Paul D, Tokgözoğlu, Lale, Vladutiu, Georgirene D, Gencer, Baris, Stock, Jane K, Ginsberg, Henry N, Chapman, M John

Get full text

Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol by Tietjen, Ian, Hovingh, G Kees, Singaraja, Roshni R, Radomski, Chris, Barhdadi, Amina, McEwen, Jason, Chan, Elden, Mattice, Maryanne, Legendre, Annick, Franchini, Patrick L, Dubé, Marie-Pierre, Kastelein, John J P, Hayden, Michael R

Get full text

Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production by Viaud, Manon, Ivanov, Stoyan, Vujic, Nemanja, Duta-Mare, Madalina, Aira, Lazaro-Emilio, Barouillet, Thibault, Garcia, Elsa, Orange, Francois, Dugail, Isabelle, Hainault, Isabelle, Stehlik, Christian, Marchetti, Sandrine, Boyer, Laurent, Guinamard, Rodolphe, Foufelle, Fabienne, Bochem, Andrea, Hovingh, Kees G, Thorp, Edward B, Gautier, Emmanuel L, Kratky, Dagmar, Dasilva-Jardine, Paul, Yvan-Charvet, Laurent

Get full text