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Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene
by
Wickliffe, Jeffrey K.
,
Herring, Stacy M.
,
Hallberg, Lance M.
,
Galbert, Lori A.
,
Masters, Oscar E.
,
Ammenheuser, Marinel M.
,
Xie, Jingwu
,
Friedberg, Errol C.
,
Lloyd, R. Stephen
,
Abdel-Rahman, Sherif Z.
,
Ward, Jonathan B.
Published in
Chemico-biological interactions
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Journal Title
Chemico-Biological Interactions
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Subjects
Animals
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Biochemistry & Molecular Biology
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Biotransformation
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1
Butadiene
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Butadienes - Toxicity
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Dna Damage
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Dna Repair - Drug Effects
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Epoxide
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Epoxide Hydrolase
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Epoxide Hydrolases - Deficiency
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Epoxy Compounds - Pharmacokinetics
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Epoxy Compounds - Toxicity
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Female
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Hprt
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Humans
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Hypoxanthine Phosphoribosyltransferase - Genetics
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Inactivation, Metabolic
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Inhalation
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Inhalation Exposure
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Injections, Intraperitoneal
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Sciencedirect
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Elsevier
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