Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality by Dang, Mai T., Gonzalez, Michael V., Gaonkar, Krutika S., Rathi, Komal S., Young, Patricia, Arif, Sherjeel, Zhai, Li, Alam, Zahidul, Devalaraja, Samir, To, Tsun Ki Jerrick, Folkert, Ian W., Raman, Pichai, Rokita, Jo Lynne, Martinez, Daniel, Taroni, Jaclyn N., Shapiro, Joshua A., Greene, Casey S., Savonen, Candace, Mafra, Fernanda, Hakonarson, Hakon, Curran, Tom, Haldar, Malay

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annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions by Gaonkar, Krutika S, Marini, Federico, Rathi, Komal S, Jain, Payal, Zhu, Yuankun, Chimicles, Nicholas A, Brown, Miguel A, Naqvi, Ammar S, Zhang, Bo, Storm, Phillip B, Maris, John M, Raman, Pichai, Resnick, Adam C, Strauch, Konstantin, Taroni, Jaclyn N, Rokita, Jo Lynne

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Identification of factors associated with duplicate rate in ChIP-seq data by Tian, Shulan, Peng, Shuxia, Kalmbach, Michael, Gaonkar, Krutika S, Bhagwate, Aditya, Ding, Wei, Eckel-Passow, Jeanette, Yan, Huihuang, Slager, Susan L

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Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality by Dang, Mai T., Gonzalez, Michael V., Gaonkar, Krutika S., Rathi, Komal S., Young, Patricia, Arif, Sherjeel, Zhai, Li, Alam, Zahidul, Devalaraja, Samir, Jerrick To, Tsun Ki, Folkert, Ian W., Raman, Pichai, Rokita, Jo Lynne, Martinez, Daniel, Taroni, Jaclyn N., Shapiro, Joshua A., Greene, Casey S., Savonen, Candace, Mafra, Fernanda, Hakonarson, Hakon, Curran, Tom, Haldar, Malay

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Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer by Reva, Boris, Chowdhury, Shrabanti, Ji, Jiayi, Whiteaker, Jeffrey R., Colaprico, Antonio, Raman, Pichai, Guo, Yiran, Brown, Miguel A., Ivey, Richard G., Szpyt, John, Guha Thakurta, Sanjukta, Lopez, Gonzalo, Kalayci, Selim, Gümüş, Zeynep H., Yoo, Seungyeul, da Veiga Leprevost, Felipe, Katsnelson, Lizabeth, Wang, Ying, Kennedy, Jacob J., Voytovich, Uliana J., Zhao, Lei, Baubet, Valerie, Tauhid, Lamiya, Lilly, Jena V., Mason, Jennifer L., Farrow, Bailey, Young, Nathan, Leary, Sarah, Moon, Jamie, Petyuk, Vladislav A., Nazarian, Javad, Palmer, James N., Lober, Robert M., Rivero-Hinojosa, Samuel, Wang, Joshua M., Broberg, Matilda, Chu, Rosalie K., Moore, Ronald J., Monroe, Matthew E., Zhao, Rui, Zhu, Jun, Mesri, Mehdi, Boja, Emily, Hiltke, Tara, Rodriguez, Henry, Zhang, Bing, Mani, D.R., Iavarone, Antonio, Schürer, Stephan, Chen, Xi S., Heath, Allison P., Rokita, Jo Lynne, Nesvizhskii, Alexey I., Fenyö, David, Rodland, Karin D., Liu, Tao, Paulovich, Amanda G., Resnick, Adam C., Storm, Phillip B., Rood, Brian R., Wang, Pei, Morgan, Allison M., Waanders, Angela J., Buccoliero, Anna Maria, Leonard, Carina A., Kline, Cassie N., Li, Chunde, Kram, David E., Hanson, Derek, Appert, Elizabeth, Kawaler, Emily A., Raabe, Eric H., Jackson, Eric M., Greenfield, Jeffrey P., Pollack, Ian F., Cain, Jason E., Foster, Jessica B., Palma, July E., Ketchum, Karen A., Blumenberg, Lili, Cornwell, Macintosh, Sarmady, Mahdi, Domagalski, Marcin J., Cieślik, Marcin P., Li, Marilyn M., Wyczalkowski, Matthew A., Connors, Meghan, Gupta, Nalin, Edwards, Nathan J., Vaske, Olena M., Becher, Oren, Firestein, Ron, Mueller, Sabine, Winebrake, Samuel G., Dhanasekaran, Saravana Mohan, Cai, Shuang, Patton, Tatiana, Lorentzen, Travis D., Liu, Wenke, Bocik, William E.

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Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003 by Kline, Cassie, Jain, Payal, Kilburn, Lindsay, Bonner, Erin R, Gupta, Nalin, Crawford, John R, Banerjee, Anu, Packer, Roger J, Villanueva-Meyer, Javier, Luks, Tracy, Zhang, Yalan, Kambhampati, Madhuri, Zhang, Jie, Yadavilli, Sridevi, Zhang, Bo, Gaonkar, Krutika S, Rokita, Jo Lynne, Kraya, Adam, Kuhn, John, Liang, Winnie, Byron, Sara, Berens, Michael, Molinaro, Annette, Prados, Michael, Resnick, Adam, Waszak, Sebastian M, Nazarian, Javad, Mueller, Sabine

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Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design by Rokita, Jo Lynne, Rathi, Komal S., Cardenas, Maria F., Upton, Kristen A., Jayaseelan, Joy, Cross, Katherine L., Pfeil, Jacob, Egolf, Laura E., Way, Gregory P., Farrel, Alvin, Kendsersky, Nathan M., Patel, Khushbu, Gaonkar, Krutika S., Modi, Apexa, Berko, Esther R., Lopez, Gonzalo, Vaksman, Zalman, Mayoh, Chelsea, Nance, Jonas, McCoy, Kristyn, Haber, Michelle, Evans, Kathryn, McCalmont, Hannah, Bendak, Katerina, Böhm, Julia W., Marshall, Glenn M., Tyrrell, Vanessa, Kalletla, Karthik, Braun, Frank K., Qi, Lin, Du, Yunchen, Zhang, Huiyuan, Lindsay, Holly B., Zhao, Sibo, Shu, Jack, Baxter, Patricia, Morton, Christopher, Kurmashev, Dias, Zheng, Siyuan, Chen, Yidong, Bowen, Jay, Bryan, Anthony C., Leraas, Kristen M., Coppens, Sara E., Doddapaneni, HarshaVardhan, Momin, Zeineen, Zhang, Wendong, Sacks, Gregory I., Hart, Lori S., Krytska, Kateryna, Mosse, Yael P., Gatto, Gregory J., Sanchez, Yolanda, Greene, Casey S., Diskin, Sharon J., Vaske, Olena Morozova, Haussler, David, Gastier-Foster, Julie M., Kolb, E. Anders, Gorlick, Richard, Li, Xiao-Nan, Reynolds, C. Patrick, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Lock, Richard B., Raman, Pichai, Wheeler, David A., Maris, John M.

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Recurrent MSCE116K mutations in ALK-negative anaplastic large cell lymphoma by Luchtel, Rebecca A., Zimmermann, Michael T., Hu, Guangzhen, Dasari, Surendra, Jiang, Manli, Oishi, Naoki, Jacobs, Hailey K., Zeng, Yu, Hundal, Tanya, Rech, Karen L., Ketterling, Rhett P., Lee, Jeong-Heon, Eckloff, Bruce W., Yan, Huihuang, Gaonkar, Krutika S., Tian, Shulan, Ye, Zhenqing, Kadin, Marshall E., Sidhu, Jagmohan, Jiang, Liuyan, Voss, Jesse, Link, Brian K., Syrbu, Sergei I., Facchetti, Fabio, Bennani, N. Nora, Slager, Susan L., Ordog, Tamas, Kocher, Jean-Pierre, Cerhan, James R., Ansell, Stephen M., Feldman, Andrew L.

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Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR... by Stundon, Jennifer L, Ijaz, Heba, Gaonkar, Krutika S, Kaufman, Rebecca S, Jin, Run, Karras, Anastasios, Vaksman, Zalman, Kim, Jung, Corbett, Ryan J, Lueder, Matthew R, Miller, Daniel P, Guo, Yiran, Santi, Mariarita, Li, Marilyn, Lopez, Gonzalo, Storm, Phillip B, Resnick, Adam C, Waanders, Angela J, MacFarland, Suzanne P, Stewart, Douglas R, Diskin, Sharon J, Rokita, Jo Lynne, Cole, Kristina A

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Pediatric high-grade glioma resources from the Children’s Brain Tumor Tissue Consortium by Ijaz, Heba, Koptyra, Mateusz, Gaonkar, Krutika S, Rokita, Jo Lynne, Baubet, Valerie P, Tauhid, Lamiya, Zhu, Yuankun, Brown, Miguel, Lopez, Gonzalo, Zhang, Bo, Diskin, Sharon J, Vaksman, Zalman, Mason, Jennifer L, Appert, Elizabeth, Lilly, Jena, Lulla, Rishi, De Raedt, Thomas, Heath, Allison P, Felmeister, Alex, Raman, Pichai, Nazarian, Javad, Santi, Maria Rita, Storm, Phillip B, Resnick, Adam, Waanders, Angela J, Cole, Kristina A

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Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix by Heim, Joel B., Squirewell, Edwin J., Neu, Ancilla, Zocher, Georg, Sominidi-Damodaran, Sindhuja, Wyles, Saranya P., Nikolova, Ekaterina, Behrendt, Nille, Saunte, Ditte M., Lock-Andersen, Jorgen, Gaonkar, Krutika S., Yan, Huihuang, Sarkaria, Jann N., Krendel, Mira, van Deursen, Jan, Sprangers, Remco, Stehle, Thilo, Böttcher, Ralph T., Lee, Jeong-Heon, Ordog, Tamas, Meves, Alexander

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Abstract 445: Integrated proteogenomic characterization across seven histological types of pediatric brain tumors by Petralia, Francesca, Tignor, Nicole, Reva, Boris, Raman, Pichai, Chowdhury, Shrabanti, Rykunov, Dmitry, Krek, Azra, Ma, Weiping, Ji, Jiayi, Song, Xiaoyu, Zhu, Yuankun, Rokita, Jo Lynne, Colaprico, Antonio, Calinawan, Anna, Whiteaker, Jeffrey R., Ivey, Richard G., Gumus, Zeynep, Kalayci, Selim, Garcia, Gonzalo L., Yoo, Seungyeul, Katsnelson, Lizabeth, Wang, Ying, Kennedy, Jacob J., Voytovich, Uliana J., Zhao, Lei, Leprevost, Felipe, Chang, Hui-Yin, Gaonkar, Krutika S., Appert, Elizabeth M., Cuellar, Ximena, Lilly, Jena, Zhu, Jun, Schadt, Eric E., Mesri, Medhi, Boja, Emily, Hiltka, Tara, Rodriguez, Henry, Ding, Li, Iavarone, Antonio, Wiznerowicz, Maciej, Nesvizhskii, Alexey I., Fenyo, David, Gygi, Steven, Paulovich, Amanda, Resnick, Adam C., Storm, Phillip B., Rood, Brian, Wang, Pei

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OpenPBTA: The Open Pediatric Brain Tumor Atlas by Shapiro, Joshua A., Gaonkar, Krutika S., Spielman, Stephanie J., Savonen, Candace L., Bethell, Chante J., Jin, Run, Rathi, Komal S., Zhu, Yuankun, Egolf, Laura E., Farrow, Bailey K., Miller, Daniel P., Yang, Yang, Koganti, Tejaswi, Noureen, Nighat, Koptyra, Mateusz P., Duong, Nhat, Santi, Mariarita, Kim, Jung, Robins, Shannon, Storm, Phillip B., Mack, Stephen C., Lilly, Jena V., Xie, Hongbo M., Jain, Payal, Raman, Pichai, Rood, Brian R., Lulla, Rishi R., Nazarian, Javad, Kraya, Adam A., Vaksman, Zalman, Heath, Allison P., Kline, Cassie, Scolaro, Laura, Viaene, Angela N., Huang, Xiaoyan, Way, Gregory P., Foltz, Steven M., Zhang, Bo, Poetsch, Anna R., Mueller, Sabine, Ennis, Brian M., Prados, Michael, Diskin, Sharon J., Zheng, Siyuan, Guo, Yiran, Kannan, Shrivats, Waanders, Angela J., Margol, Ashley S., Kim, Meen Chul, Hanson, Derek, Van Kuren, Nicholas, Wong, Jessica, Kaufman, Rebecca S., Coleman, Noel, Blackden, Christopher, Cole, Kristina A., Mason, Jennifer L., Madsen, Peter J., Koschmann, Carl J., Stewart, Douglas R., Wafula, Eric, Brown, Miguel A., Resnick, Adam C., Greene, Casey S., Rokita, Jo Lynne, Taroni, Jaclyn N.

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Computational evaluation of small molecule inhibitors of RGS4 to regulate the dopaminergic control of striatal LTD by Gaonkar, Krutika Satish, Gulati, Gavish, Balu, K., Purohit, Rituraj

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Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma by Luchtel, Rebecca A, Zimmermann, Michael T, Hu, Guangzhen, Dasari, Surendra, Jiang, Manli, Oishi, Naoki, Jacobs, Hailey K, Zeng, Yu, Hundal, Tanya, Rech, Karen L, Ketterling, Rhett P, Lee, Jeong-Heon, Eckloff, Bruce W, Yan, Huihuang, Gaonkar, Krutika S, Tian, Shulan, Ye, Zhenqing, Kadin, Marshall E, Sidhu, Jagmohan, Jiang, Liuyan, Voss, Jesse, Link, Brian K, Syrbu, Sergei I, Facchetti, Fabio, Bennani, N Nora, Slager, Susan L, Ordog, Tamas, Kocher, Jean-Pierre, Cerhan, James R, Ansell, Stephen M, Feldman, Andrew L

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Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes by Lomberk, Gwen, Blum, Yuna, Nicolle, Rémy, Nair, Asha, Gaonkar, Krutika Satish, Marisa, Laetitia, Mathison, Angela, Sun, Zhifu, Yan, Huihuang, Elarouci, Nabila, Armenoult, Lucile, Ayadi, Mira, Ordog, Tamas, Lee, Jeong-Heon, Oliver, Gavin, Klee, Eric, Moutardier, Vincent, Gayet, Odile, Bian, Benjamin, Duconseil, Pauline, Gilabert, Marine, Bigonnet, Martin, Garcia, Stephane, Turrini, Olivier, Delpero, Jean-Robert, Giovannini, Marc, Grandval, Philippe, Gasmi, Mohamed, Secq, Veronique, De Reyniès, Aurélien, Dusetti, Nelson, Iovanna, Juan, Urrutia, Raul

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CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity by Karakashev, Sergey, Zhu, Hengrui, Wu, Shuai, Yokoyama, Yuhki, Bitler, Benjamin G., Park, Pyoung-Hwa, Lee, Jeong-Heon, Kossenkov, Andrew V., Gaonkar, Krutika Satish, Yan, Huihuang, Drapkin, Ronny, Conejo-Garcia, Jose R., Speicher, David W., Ordog, Tamas, Zhang, Rugang

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HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4 + CD8 + thymocytes for CD4-lineage commitment by Philips, Rachael Laura, Lee, Jeong-Heon, Gaonkar, Krutika, Chanana, Pritha, Chung, Ji Young, Romero Arocha, Sinibaldo R, Schwab, Aaron, Ordog, Tamas, Shapiro, Virginia Smith

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A tailored approach to fusion transcript identification increases diagnosis of rare inherited disease by Oliver, Gavin R, Tang, Xiaojia, Schultz-Rogers, Laura E, Vidal-Folch, Noemi, Jenkinson, W Garrett, Schwab, Tanya L, Gaonkar, Krutika, Cousin, Margot A, Nair, Asha, Basu, Shubham, Chanana, Pritha, Oglesbee, Devin, Klee, Eric W

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Harmonization of postmortem donations for pediatric brain tumors and molecular characterization of diffuse midline gliomas by Kambhampati, Madhuri, Panditharatna, Eshini, Yadavilli, Sridevi, Saoud, Karim, Lee, Sulgi, Eze, Augustine, Almira-Suarez, M. I., Hancock, Lauren, Bonner, Erin R., Gittens, Jamila, Stampar, Mojca, Gaonkar, Krutika, Resnick, Adam C., Kline, Cassie, Ho, Cheng-Ying, Waanders, Angela J., Georgescu, Maria-Magdalena, Rance, Naomi E., Kim, Yong, Johnson, Courtney, Rood, Brian R., Kilburn, Lindsay B., Hwang, Eugene I., Mueller, Sabine, Packer, Roger J., Bornhorst, Miriam, Nazarian, Javad

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