Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase by Jani, Krupa S., Jain, Siddhant U., Ge, Eva J., Diehl, Katharine L., Lundgren, Stefan M., Müller, Manuel M., Lewis, Peter W., Muir, Tom W.

Get full text

PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor by Diehl, Katharine L., Ge, Eva J., Weinberg, Daniel N., Jani, Krupa S., Allis, C. David, Muir, Tom W.

Get full text

Temporally Controlled Targeting of 4‑Hydroxynonenal to Specific Proteins in Living Cells by Fang, Xinqiang, Fu, Yuan, Long, Marcus J. C, Haegele, Joseph A, Ge, Eva J, Parvez, Saba, Aye, Yimon

Get full text

Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes by Mashtalir, Nazar, Dao, Hai T, Sankar, Akshay, Liu, Hengyuan, Corin, Aaron J, Bagert, John D, Ge, Eva J, D'Avino, Andrew R, Filipovski, Martin, Michel, Brittany C, Dann, Geoffrey P, Muir, Tom W, Kadoch, Cigall

Get full text

Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates by Toh, Joel D. W., Crossley, Steven W. M., Bruemmer, Kevin J., Ge, Eva J., He, Dan, Iovan, Diana A., Chang, Christopher J.

Get full text

Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin by Leicher, Rachel, Ge, Eva J., Lin, Xingcheng, Reynolds, Matthew J., Xie, Wenjun, Walz, Thomas, Zhang, Bin, Muir, Tom W., Liu, Shixin

Get full text

Formaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism by Pham, Vanha N, Bruemmer, Kevin J, Toh, Joel D W, Ge, Eva J, Tenney, Logan, Ward, Carl C, Dingler, Felix A, Millington, Christopher L, Garcia-Prieto, Carlos A, Pulos-Holmes, Mia C, Ingolia, Nicholas T, Pontel, Lucas B, Esteller, Manel, Patel, Ketan J, Nomura, Daniel K, Chang, Christopher J

Get full text

Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric Constraints and Impact of the Regulatory Subunit JARID2 by Ge, Eva J, Jani, Krupa S, Diehl, Katharine L, Müller, Manuel M, Muir, Tom W

Get full text

The R-Process Alliance: First Release from the Northern Search for r-process-enhanced Metal-poor Stars in the Galactic Halo by Sakari, Charli M., Placco, Vinicius M., Farrell, Elizabeth M., Roederer, Ian U., Wallerstein, George, Beers, Timothy C., Ezzeddine, Rana, Frebel, Anna, Hansen, Terese, Holmbeck, Erika M., Sneden, Christopher, Cowan, John J., Venn, Kim A., Davis, Christopher Evan, Matijevi, Gal, Wyse, Rosemary F. G., Bland-Hawthorn, Joss, Chiappini, Cristina, Freeman, Kenneth C., Gibson, Brad K., Grebel, Eva K., Helmi, Amina, Kordopatis, Georges, Kunder, Andrea, Navarro, Julio, Reid, Warren, Seabroke, George, Steinmetz, Matthias, Watson, Fred

Get full text

Original Research Minimally important differences for interpreting EORTC QLQ-C30 change scores over time: A synthesis across 21 clinical trials involving nine different cancer type... by Musoro, JZ, Coens, C, Sprangers, MAG, Brandberg, Y, Groenvold, M, Flechtner, H-H, Cocks, K, Velikova, G, Dirven, L, Greimel, E

Get full text

A trial to evaluate the effect of the sodium–glucose co‐transporter 2 inhibitor dapagliflozin on morbidity and mortality in patients with heart failure and reduced left ventricular... by McMurray, John J.V., DeMets, David L., Inzucchi, Silvio E., Køber, Lars, Kosiborod, Mikhail N., Langkilde, Anna M., Martinez, Felipe A., Bengtsson, Olof, Ponikowski, Piotr, Sabatine, Marc S., Sjöstrand, Mikaela, Solomon, Scott D., McMurray, John JV, DeMets, David L, Inzucchi, Silvio E, Køber, Lars, Kosiborod, Mikhail N, Langkilde, Anna Maria, Martinez, Felipe A, Ponikowski, Piotr, Sabatine, Marc S, Sjöstrand, Mikaela, Solomon, Scott D, Diez, Mirta, Nicolau, Jose, Katova, Tzvetana, O'Meara, Eileen, Howlett, Jonathan, Verma, Subodh, Ge, Junbo, Belohlavek, Jan, Schou, Morten, Böhm, Michael, Merkely, Bela, Chopra, Vijay, Kitakaze, Masafumi, de Boer, Rudolf A., Drozdz, Jaroslaw, Tereshchenko, Sergey, Dukat, Andrej, Ljungman, Charlotta, Chiang, Chern‐En, Petrie, Mark, Desai, Akshay, Anand, Inder, Pham, Vinh Nguyen, Pfeffer, Marc A., Pocock, Stuart, Swedberg, Karl, Rouleau, Jean L., Chaturvedi, Nishi, Ivanovich, Peter, Levey, Andrew S., Christ‐Schmidt, Heidi, Held, Claes, Varenhorst, Christoph, Christersson, Christina, Mann, Johannes, Holmgren, Pernilla, Hallberg, Theresa, Langkilde, AnnaMaria, Sjöstrand, Mikaela, Denison, Hans, Reicher, Barry, Bengtsson, Olof, Fox, Ywonne, Forsby, Mikael, Alenhag, Eva‐Lena, Nilsson, Ann, Kazanowska, Kinga, Olofsson, Eva Lavik, Karup, Cathrine, Ekedahl‐Berggren, Maria, Klockargård, Anna‐Lena, Kempe, Karin, Selvén, Mathilda

Get full text

Effects of Sacubitril-Valsartan Versus Valsartan in Women Compared With Men With Heart Failure and Preserved Ejection Fraction: Insights From PARAGON-HF by McMurray, John J.V., Jackson, Alice M., Lam, Carolyn S.P., Redfield, Margaret M., Anand, Inder S., Ge, Junbo, Lefkowitz, Marty P., Maggioni, Aldo P., Martinez, Felipe, Packer, Milton, Pfeffer, Marc A., Pieske, Burkert, Rizkala, Adel R., Sabarwal, Shalini V., Shah, Amil M., Shah, Sanjiv J., Shi, Victor C., van Veldhuisen, Dirk J., Zannad, Faiez, Zile, Michael R., Cikes, Maja, Goncalvesova, Eva, Katova, Tzvetana, Kosztin, Anamaria, Lelonek, Malgorzata, Sweitzer, Nancy, Vardeny, Orly, Claggett, Brian, Jhund, Pardeep S., Solomon, Scott D.

Get full text

Mid-Pleistocene climate transition drives net mass loss from rapidly uplifting St. Elias Mountains, Alaska by Gulick, Sean P. S., Jaeger, John M., Mix, Alan C., Asahi, Hirofumi, Bahlburg, Heinrich, Belanger, Christina L., Berbel, Glaucia B. B., Childress, Laurel, Cowan, Ellen, Drab, Laureen, Forwick, Matthias, Fukumura, Akemi, Ge, Shulan, Gupta, Shyam, Kioka, Arata, Konno, Susumu, LeVay, Leah J., März, Christian, Matsuzaki, Kenji M., McClymont, Erin L., Moy, Chris, Müller, Juliane, Nakamura, Atsunori, Ojima, Takanori, Ribeiro, Fabiana R., Ridgway, Kenneth D., Romero, Oscar E., Slagle, Angela L., Stoner, Joseph S., St-Onge, Guillaume, Suto, Itsuki, Walczak, Maureen D., Worthingtona, Lindsay L., Baileyb, Ian, Enkelmannc, Eva, Reeced, Robert, Swartz, John M.

Get full text

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease by Astle, William J., Elding, Heather, Jiang, Tao, Allen, Dave, Ruklisa, Dace, Mann, Alice L., Mead, Daniel, Bouman, Heleen, Riveros-Mckay, Fernando, Kostadima, Myrto A., Lambourne, John J., Sivapalaratnam, Suthesh, Downes, Kate, Kundu, Kousik, Bomba, Lorenzo, Berentsen, Kim, Bradley, John R., Daugherty, Louise C., Delaneau, Olivier, Freson, Kathleen, Garner, Stephen F., Grassi, Luigi, Guerrero, Jose, Haimel, Matthias, Janssen-Megens, Eva M., Kaan, Anita, Kamat, Mihir, Kim, Bowon, Mandoli, Amit, Marchini, Jonathan, Martens, Joost H.A., Meacham, Stuart, Megy, Karyn, O’Connell, Jared, Petersen, Romina, Sharifi, Nilofar, Sheard, Simon M., Staley, James R., Tuna, Salih, van der Ent, Martijn, Walter, Klaudia, Wang, Shuang-Yin, Wheeler, Eleanor, Wilder, Steven P., Iotchkova, Valentina, Moore, Carmel, Sambrook, Jennifer, Stunnenberg, Hendrik G., Di Angelantonio, Emanuele, Kaptoge, Stephen, Kuijpers, Taco W., Carrillo-de-Santa-Pau, Enrique, Juan, David, Rico, Daniel, Valencia, Alfonso, Chen, Lu, Ge, Bing, Vasquez, Louella, Kwan, Tony, Garrido-Martín, Diego, Watt, Stephen, Yang, Ying, Guigo, Roderic, Beck, Stephan, Paul, Dirk S., Pastinen, Tomi, Bujold, David, Bourque, Guillaume, Frontini, Mattia, Danesh, John, Roberts, David J., Ouwehand, Willem H., Butterworth, Adam S., Soranzo, Nicole

Get full text

Influenza Vaccine Effectiveness in the Netherlands from 2003/2004 through 2013/2014: The Importance of Circulating Influenza Virus Types and Subtypes by Darvishian, Maryam, Dijkstra, Frederika, van Doorn, Eva, Bijlsma, Maarten J, Donker, Gé A, de Lange, Marit M A, Cadenau, Laura M, Hak, Eelko, Meijer, Adam

Get full text

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells by Chen, Lu, Ge, Bing, Casale, Francesco Paolo, Vasquez, Louella, Kwan, Tony, Garrido-Martín, Diego, Watt, Stephen, Yan, Ying, Kundu, Kousik, Ecker, Simone, Datta, Avik, Richardson, David, Burden, Frances, Mead, Daniel, Mann, Alice L., Fernandez, Jose Maria, Rowlston, Sophia, Wilder, Steven P., Farrow, Samantha, Shao, Xiaojian, Lambourne, John J., Redensek, Adriana, Albers, Cornelis A., Amstislavskiy, Vyacheslav, Ashford, Sofie, Berentsen, Kim, Bomba, Lorenzo, Bourque, Guillaume, Bujold, David, Busche, Stephan, Caron, Maxime, Chen, Shu-Huang, Cheung, Warren, Delaneau, Oliver, Dermitzakis, Emmanouil T., Elding, Heather, Colgiu, Irina, Bagger, Frederik O., Flicek, Paul, Habibi, Ehsan, Iotchkova, Valentina, Janssen-Megens, Eva, Kim, Bowon, Lehrach, Hans, Lowy, Ernesto, Mandoli, Amit, Matarese, Filomena, Maurano, Matthew T., Morris, John A., Pancaldi, Vera, Pourfarzad, Farzin, Rehnstrom, Karola, Rendon, Augusto, Risch, Thomas, Sharifi, Nilofar, Simon, Marie-Michelle, Sultan, Marc, Valencia, Alfonso, Walter, Klaudia, Wang, Shuang-Yin, Frontini, Mattia, Antonarakis, Stylianos E., Clarke, Laura, Yaspo, Marie-Laure, Beck, Stephan, Guigo, Roderic, Rico, Daniel, Martens, Joost H.A., Ouwehand, Willem H., Kuijpers, Taco W., Paul, Dirk S., Stunnenberg, Hendrik G., Stegle, Oliver, Downes, Kate, Pastinen, Tomi, Soranzo, Nicole

Get full text

Pre‐ and Postnatal Transplantation of Fetal Mesenchymal Stem Cells in Osteogenesis Imperfecta: A Two‐Center Experience by Götherström, Cecilia, Westgren, Magnus, Shaw, S.W. Steven, Åström, Eva, Biswas, Arijit, Byers, Peter H., Mattar, Citra N.Z., Graham, Gail E., Taslimi, Jahan, Ewald, Uwe, Fisk, Nicholas M., Yeoh, Allen E.J., Lin, Ju-Li, Cheng, Po-Jen, Choolani, Mahesh, Le Blanc, Katarina, Chan, Jerry K.Y.

Request full text

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry by Hoeks, Marlijn, Yu, Ge, Langemeijer, Saskia, Crouch, Simon, de Swart, Louise, Fenaux, Pierre, Symeonidis, Argiris, Čermák, Jaroslav, Hellström-Lindberg, Eva, Sanz, Guillermo, Stauder, Reinhard, Holm, Mette Skov, Mittelman, Moshe, Mądry, Krzysztof, Malcovati, Luca, Tatic, Aurelia, Almeida, Antonio Medina, Germing, Ulrich, Savic, Aleksandar, Šimec, Njetočka Gredelj, Culligan, Dominic, Itzykson, Raphael, Guerci-Bresler, Agnes, Slama, Borhane, Droste, Jackie, van Marrewijk, Corine, van de Loosdrecht, Arjan, Blijlevens, Nicole, van Kraaij, Marian, Bowen, David, de Witte, Theo, Smith, Alex

Get full text

Hypoxia-inducible factor 1α stabilization by carbon monoxide results in cytoprotective preconditioning by Chin, Beek Y, Jiang, Ge, Wegiel, Barbara, Wang, Hong J, MacDonald, Theresa, Zhang, Xu Chen, Gallo, David, Cszimadia, Eva, Bach, Fritz H, Lee, Patty J, Otterbein, Leo E

Get full text

Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I by Sokolowska, Milena, Rovati, G. Enrico, Diamant, Zuzana, Untersmayr, Eva, Schwarze, Jargen, Lukasik, Zuzanna, Sava, Florentina, Angelina, Alba, Palomares, Oscar, Akdis, Cezmi A., O’Mahony, Liam, Sanak, Marek, Dahlen, Sven‐Erik, Woszczek, Grzegorz

Get full text