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First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors
by
Janku, Filip
,
Beom, Seung-Hoon
,
Moon, Yong Wha
,
Kim, Tae Won
,
Shin, Young G.
,
Yim, Dong-Seok
,
Kim, Gun Min
,
Kim, Hyo Song
,
Kim, Sun Young
,
Cheong, Jae-Ho
,
Lee, Young Woo
,
Geiger, Barb
,
Yoo, Sanghee
,
Thurston, Archie
,
Welsch, Dean
,
Rudoltz, Marc S.
,
Rha, Sun Young
Published in
Investigational new drugs
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Investigational New Drugs
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Subjects
Anticancer Properties
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Antineoplastic Agents - Adverse Effects
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Antitumor Activity
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Biguanide
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Biguanides - Therapeutic Use
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Cancer
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Clinical Trial
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Constipation
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Diarrhea
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Dose-Response Relationship, Drug
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Humans
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Im156
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Inhibitors
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Lactic Acid
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Life Sciences & Biomedicine
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Maximum Tolerated Dose
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Medicine
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Medicine & Public Health
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Mitochondria
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Nausea
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Springer Nature
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Abi/Inform Global
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Springer Online Journal Archives (Through 1996)
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Springerlink Contemporary 1997-Present
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