Structure–activity relationship study of 4-substituted piperidines at Leu26 moiety of novel p53–hDM2 inhibitors by Tian, Yuan, Ma, Yao, Gibeau, Craig R., Lahue, Brian R., Shipps, Gerald W., Strickland, Corey, Bogen, Stéphane L.

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Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors by Bogen, Stéphane L, Pan, Weidong, Gibeau, Craig R, Lahue, Brian R, Ma, Yao, Nair, Latha G, Seigel, Elise, Shipps, Gerald W, Tian, Yuan, Wang, Yaolin, Lin, Yinghui, Liu, Ming, Liu, Suxing, Mirza, Asra, Wang, Xiaoying, Lipari, Philip, Seidel-Dugan, Cynthia, Hicklin, Daniel J, Bishop, W. Robert, Rindgen, Diane, Nomeir, Amin, Prosise, Winifred, Reichert, Paul, Scapin, Giovanna, Strickland, Corey, Doll, Ronald J

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Pivotal Role of an Aliphatic Side Chain in the Development of an HDM2 Inhibitor by Ma, Yao, Lahue, Brian R, Gibeau, Craig R, Shipps, Gerald W, Bogen, Stéphane L, Wang, Yaolin, Guo, Zhuyan, Guzi, Timothy J

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The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer by Quiroz, Ryan V, Reutershan, Michael H, Schneider, Sebastian E, Sloman, David, Lacey, Brian M, Swalm, Brooke M, Yeung, Charles S, Gibeau, Craig, Spellman, Daniel S, Rankic, Danica A, Chen, Dapeng, Witter, David, Linn, Doug, Munsell, Erik, Feng, Guo, Xu, Haiyan, Hughes, Jonathan M. E, Lim, Jongwon, Saurí, Josep, Geddes, Kristin, Wan, Murray, Mansueto, My Sam, Follmer, Nicole E, Fier, Patrick S, Siliphaivanh, Phieng, Daublain, Pierre, Palte, Rachel L, Hayes, Robert P, Lee, Sandra, Kawamura, Shuhei, Silverman, Steven, Sanyal, Sulagna, Henderson, Timothy J, Ye, Yingchun, Gao, Yuanwei, Nicholson, Benjamin, Machacek, Michelle R

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Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors by Simov, Vladimir, Deshmukh, Sujal V., Dinsmore, Christopher J., Elwood, Fiona, Fernandez, Rafael B., Garcia, Yudith, Gibeau, Craig, Gunaydin, Hakan, Jung, Joon, Katz, Jason D., Kraybill, Brian, Lapointe, Blair, Patel, Sangita B., Siu, Tony, Su, Hua, Young, Jonathan R.

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Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors by Huang, Chunhui, Fischer, Christian, Machacek, Michelle R, Bogen, Stephane, Biftu, Tesfaye, Huang, Xianhai, Reutershan, Michael H, Otte, Ryan, Hong, Qingmei, Wu, Zhicai, Yu, Yang, Park, Min, Chen, Lei, Biju, Purakkattle, Knemeyer, Ian, Lu, Ping, Kochansky, Christopher J, Hicks, Michael Brendan, Liu, Yong, Helmy, Roy, Fradera, Xavier, Donofrio, Anthony, Close, Josh, Maddess, Matthew L, White, Catherine, Sloman, David L, Sciammetta, Nunzio, Lu, Jun, Gibeau, Craig, Simov, Vladimir, Zhang, Hongjun, Fuller, Peter, Witter, David

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