WIP1 phosphatase as a potential therapeutic target in neuroblastoma by Richter, Mark, Dayaram, Tajhal, Gilmartin, Aidan G, Ganji, Gopinath, Pemmasani, Sandhya Kiran, Van Der Key, Harjeet, Shohet, Jason M, Donehower, Lawrence A, Kumar, Rakesh

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In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor by Gilmartin, Aidan G, Groy, Arthur, Gore, Elizabeth R, Atkins, Charity, Long, Edward R, Montoute, Monica N, Wu, Zining, Halsey, Wendy, McNulty, Dean E, Ennulat, Daniela, Rueda, Lourdes, Pappalardi, Melissa, Kruger, Ryan G, McCabe, Michael T, Raoof, Ali, Butlin, Roger, Stowell, Alexandra, Cockerill, Mark, Waddell, Ian, Ogilvie, Donald, Luengo, Juan, Jordan, Allan, Benowitz, Andrew B

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Distinct Concentration-Dependent Effects of the Polo-like Kinase 1―Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis by GILMARTIN, Aidan G, BLEAM, Maureen R, SUTTON, David, DIAMOND, Melody A, JACKSON, Jeffrey R, LAQUERRE, Sylvie G, RICHTER, Mark C, ERSKINE, Symon G, KRUGER, Ryan G, MADDEN, Lenore, HASSLER, Daniel F, SMITH, Gary K, GONTAREK, Richard R, COURTNEY, Mary P

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Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate) by Abe, Hiroyuki, Kikuchi, Shinichi, Hayakawa, Kazuhide, Iida, Tetsuya, Nagahashi, Noboru, Maeda, Katsuya, Sakamoto, Johei, Matsumoto, Noriaki, Miura, Tomoya, Matsumura, Koji, Seki, Noriyoshi, Inaba, Takashi, Kawasaki, Hisashi, Yamaguchi, Takayuki, Kakefuda, Reina, Nanayama, Toyomichi, Kurachi, Hironori, Hori, Yoshikazu, Yoshida, Takayuki, Kakegawa, Junya, Watanabe, Yoshihiro, Gilmartin, Aidan G, Richter, Mark C, Moss, Katherine G, Laquerre, Sylvie G

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GSK1120212 (JTP-74057) Is an Inhibitor of MEK Activity and Activation with Favorable Pharmacokinetic Properties for Sustained In Vivo Pathway Inhibition by GILMARTIN, Aidan G, BLEAM, Maureen R, ZAPPACOSTA, Francesca, ANNAN, Roland, SUTTON, David, LAQUERRE, Sylvie G, GROY, Arthur, MOSS, Katherine G, MINTHORN, Elisabeth A, KULKARNI, Swarupa G, ROMINGER, Cynthia M, ERSKINE, Symon, FISHER, Kelly E, JINGSONG YANG

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A hit deconstruction approach for the discovery of fetal hemoglobin inducers by Benowitz, Andrew B., Eberl, H. Christian, Erickson-Miller, Connie L., Gilmartin, Aidan G., Gore, Elizabeth R., Montoute, Monica N., Wu, Zining

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Antitumor activity of an allosteric inhibitor of centromere-associated protein-E by Wood, Kenneth W, Lad, Latesh, Luo, Lusong, Qian, Xiangping, Knight, Steven D, Nevins, Neysa, Brejc, Katjusa, Sutton, David, Gilmartin, Aidan G, Chua, Penelope R, Desai, Radhika, Schauer, Stephen P, McNulty, Dean E, Annan, Roland S, Belmont, Lisa D, Garcia, Carlos, Lee, Yan, Diamond, Melody A, Faucette, Leo F, Giardiniere, Michele, Zhang, ShuYun, Sun, Chiu-Mei, Vidal, Justin D, Lichtsteiner, Serge, Cornwell, William D, Greshock, Joel D, Wooster, Richard F, Finer, Jeffrey T, Copeland, Robert A, Huang, Pearl S, Morgans, David J. Jr, Dhanak, Dashyant, Bergnes, Gustave, Sakowicz, Roman, Jackson, Jeffrey R

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Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability by Degenhardt, Yan, Greshock, Joel, Laquerre, Sylvie, Gilmartin, Aidan G, Jing, Junping, Richter, Mark, Zhang, Xiping, Bleam, Maureen, Halsey, Wendy, Hughes, Ashley, Moy, Christopher, Liu-Sullivan, Nancy, Powers, Scott, Bachman, Kurtis, Jackson, Jeffrey, Weber, Barbara, Wooster, Richard

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Development and Characterization of a Model for Inducing Fetal Hemoglobin Production in Cynomolgus Macaques (Macaca fasicularis) by Kundu, Mila C, Gore, Liz R, Maguire, Sean, Gilmartin, Aidan G

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Novel receptor antagonists for cancer therapy: hedgehog pathway inhibitors by Shelton, Christopher A, Gilmartin, Aidan G

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Abstract 961: GSK1120212 inhibits both MEK kinase activity and activation by Fisher, Kelly, Yang, Jingsong, Zappacosta, Francesca, Groy, Arthur, Rominger, Cynthia, Gilmartin, Aidan G.

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Abstract C74: Reassessing IKKε as a novel oncology target by Richter, Mark C., Groy, Arthur X., Wang, Da-Yuan, Lu, Quinn, Holbrook, Joanna D., Sarpong, Martha A., Seefeld, Mark A., Smith, Danielle M., Laquerre, Sylvie G., Gilmartin, Aidan G.

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