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Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system
by
Bevacqua, R.J.
,
Fernandez-Martín, R.
,
Savy, V.
,
Canel, N.G.
,
Gismondi, M.I.
,
Kues, W.A.
,
Carlson, D.F.
,
Fahrenkrug, S.C.
,
Niemann, H.
,
Taboga, O.A.
,
Ferraris, S.
,
Salamone, D.F.
Published in
Theriogenology
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Theriogenology
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Subjects
Animals
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Bovine Spongiform Encephalopathy
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Cattle
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Cattle - Embryology
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Cattle - Genetics
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Crispr-Cas Systems
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Engineered Nuclease
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Fertilization In Vitro - Veterinary
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Fetus - Cytology
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Fibroblasts - Metabolism
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Gene Expression Regulation, Developmental
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Gene Targeting
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Genetic Engineering - Veterinary
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Life Sciences & Biomedicine
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Mad Cow Disease
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Mutation
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Prion Proteins - Genetics
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Prion Proteins - Metabolism
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Reproductive Biology
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Ruminant
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