Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial by Del Mastro, Lucia, Dr, De Placido, Sabino, Prof, Bruzzi, Paolo, MD, De Laurentiis, Michele, MD, Boni, Corrado, MD, Cavazzini, Giovanna, MD, Durando, Antonio, MD, Turletti, Anna, MD, Nisticò, Cecilia, MD, Valle, Enrichetta, MD, Garrone, Ornella, MD, Puglisi, Fabio, MD, Montemurro, Filippo, MD, Barni, Sandro, MD, Ardizzoni, Andrea, MD, Gamucci, Teresa, MD, Colantuoni, Giuseppe, MD, Giuliano, Mario, MD, Gravina, Adriano, MD, Papaldo, Paola, MD, Bighin, Claudia, MD, Bisagni, Giancarlo, MD, Forestieri, Valeria, MD, Cognetti, Francesco, MD

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Enhancer-associated H3K4 methylation safeguards in vitro germline competence by Bleckwehl, Tore, Crispatzu, Giuliano, Schaaf, Kaitlin, Respuela, Patricia, Bartusel, Michaela, Benson, Laura, Clark, Stephen J., Dorighi, Kristel M., Barral, Antonio, Laugsch, Magdalena, van IJcken, Wilfred F. J., Manzanares, Miguel, Wysocka, Joanna, Reik, Wolf, Rada-Iglesias, Álvaro

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Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial by Caroli, Anna, PhD, Perico, Norberto, MD, Perna, Annalisa, MSc, Antiga, Luca, PhD, Brambilla, Paolo, MD, Pisani, Antonio, MD, Visciano, Bianca, MD, Imbriaco, Massimo, MD, Messa, Piergiorgio, MD, Cerutti, Roberta, MD, Dugo, Mauro, MD, Cancian, Luca, MD, Buongiorno, Erasmo, MD, De Pascalis, Antonio, MD, Gaspari, Flavio, ChemD, Carrara, Fabiola, Chemist, Rubis, Nadia, Res Nurse, Prandini, Silvia, Res Nurse, Remuzzi, Andrea, EngD, Remuzzi, Giuseppe, Dr, Ruggenenti, Piero, MD

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Multiclass HCV resistance to direct‐acting antiviral failure in real‐life patients advocates for tailored second‐line therapies by Di Maio, Velia C., Cento, Valeria, Aragri, Marianna, Rossi, Piera, Verucchi, Gabriella, Magni, Carlo F., Teti, Elisabetta, Micheli, Valeria, Calvaruso, Vincenza, Gianserra, Laura, Romagnoli, Dante, Cozzolongo, Raffaele, Grieco, Antonio, Morisco, Filomena, Brancaccio, Giuseppina, Di Biagio, Antonio, Loggi, Elisabetta, Mastroianni, Claudio M., Pace Palitti, Valeria, Tarquini, Pierluigi, Puoti, Massimo, Vullo, Vincenzo, Paoloni, Maurizio, Pasquazzi, Caterina, Rizzardini, Giuliano, Parruti, Giustino, Craxì, Antonio, Babudieri, Sergio, Angelico, Mario, Ceccherini‐Silberstein, Francesca, Grimaldi, A., Verucchi, G., Menzaghi, B., Quirino, T., Torti, C., Vecchiet, J., Bruzzone, B., De Maria, A., Marenco, S., Viscoli, C., Lichtner, M., Aghemo, A., Boccaccio, V., Bruno, S., Cerrone, M., Colombo, M., Danieli, E., Donato, F., Gubertini, G., Lleo, A., Magni, C.F., Mancon, A., Monico, S., Gnocchi, M., Orro, A., Milanesi, L., Bertolotti, M., Borghi, V., Mussini, C., Gaeta, G.B., Sangiovanni, V., Di Marco, V., Mazzola, A., D'Amico, E., Cacciatore, P., Consorte, A., Pieri, A., Sozio, F., Baiocchi, L., Barbaliscia, S., Biliotti, E., Carioti, L., Cerasari, G., Cerva, C., Ciotti, M., D'Ettorre, G., De Leonardis, F., De Sanctis, A., Di Maio, V.C., Furlan, C., Gallo, P., Giannelli, V., Lattanzi, B., Lenci, I., Lula, R., Malagnino, V., Manuelli, M., Milana, M., Moretti, A., Palazzo, D., Pellicelli, A., Romano, M., Sarrecchia, C., Sorbo, M.C., Spaziante, M., Mangia, A., Maida, I., Mura, M.S., Falconi, L., Di Giammartino, D.

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Fecal Microbiota Transplant in a Pre-Clinical Model of Type 2 Diabetes Mellitus, Obesity and Diabetic Kidney Disease by Bastos, Rosana M C, Simplício-Filho, Antônio, Sávio-Silva, Christian, Oliveira, Luiz Felipe V, Cruz, Giuliano N F, Sousa, Eliza H, Noronha, Irene L, Mangueira, Cristóvão L P, Quaglierini-Ribeiro, Heloísa, Josefi-Rocha, Gleice R, Rangel, Érika B

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Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID‐19 by Anto, Josep M., Vidal, Alain, Sheikh, Aziz, Akdis, Cezmi A., Aberer, Werner, Akdis, Mübeccel, Annesi‐Maesano, Isabella, Anto, Josep, Azhari, Khuzama, Baiardini, Ilaria, Bedolla Barajas, Martín, Bernstein, David, Bialek, Slawomir, Białoszewski, Artur, Boner, Attilio, Bosnic‐Anticevich, Sinthia, Buquicchio, Rosalva, Camargos, Paulo, Carmon Pirez, Jonas, Carreiro‐Martins, Pedro, Chandrasekharan, Ramanathan, Chelninska, Marta, Christoff, George, Chua, Antonio, Cicerán, Alberto, Cirule, Ieva, Correia de Sousa, Jaime, D'Amato, Gennaro, Dahlen, Sven‐Erik, Darsow, Ulf, Blay, Frédéric, Devillier, Philippe, Djukanovic, Ratko, Durham, Stephen, Ebo, Didier, Edelbaher, Natalija, Eklund, Patrik, Enecilla, Lourdes, Farrell, John, Fernandez, Lenora, Gamkrelidze, Amiran, Gennimata, Dimitra, Gomez, Maximiliano, Grigoreas, Christos, Salina, Husain, Ivancevich, Juan‐Carlos, Julge, Kaja, Kardas, Przemyslaw, KorenJeverica, Anja, Kostov, Kosta V., Kowalski, Marek L., Kralimarkova, Tanya, Kreft, Samo, Kupczyk, Maciej, Li, Jing, Lieberman, Philip, Lobo, Rommel, Luna Pech, Jorge A., Mais, Yassin, Mandajieva, Mariana, Montefort, Steve, Münter, Lars, Nicola, Stefania, Nyembue, Dieudonné, Oliver, Brian, Onorato, Gabrielle L., Passalacqua, Giovanni, Peleve, Susete, Pereira, Ana, Perna, Andrea, Pfaar, Oliver, Pin, Isabelle, Pitsios, Constantinos, Prados‐Torres, Alexandra, Prarros, Fotis, Recto, Marysia T., Ridolo, Erminia, Rodríguez González, Mónica, Rolla, Giovanni, Roman Rodriguez, Miguel, Rombaux, Philippe, Rozman Sinur, Irma, Ruiz Segura, Lucy Tania, Salimaki, Johanna, Sawaf, Bisher, Senna, Gianenrico, Sitkauskiene, Brigita, Specjalski, Krzysztof, Subramaniam, Abirami, Tomic‐Spiric, Vesna, Uberti, M., Vallianatou, Mina, Vassileva, Dafina, Vera‐Munoz, Cécilia, Vicheva, Dilyana, Vichyanond, Pakit, Wallace, Dana, Yawn, Barbara, Zaitoun, Fares, Zidarn, Mihaela

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Switch to Dolutegravir plus Rilpivirine Dual Therapy in cART-Experienced Subjects: An Observational Cohort by Capetti, Amedeo F, Sterrantino, Gaetana, Cossu, Maria Vittoria, Orofino, GianCarlo, Barbarini, Giorgio, De Socio, Giuseppe V, Di Giambenedetto, Simona, Di Biagio, Antonio, Celesia, Benedetto M, Argenteri, Barbara, Rizzardini, Giuliano

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Age and Multimorbidity Predict Death Among COVID-19 Patients: Results of the SARS-RAS Study of the Italian Society of Hypertension by Iaccarino, Guido, Grassi, Guido, Borghi, Claudio, Ferri, Claudio, Salvetti, Massimo, Volpe, Massimo

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High sodium and low potassium intake among Italian children: relationship with age, body mass and blood pressure by Campanozzi, Angelo, Avallone, Sonia, Barbato, Antonio, Iacone, Roberto, Russo, Ornella, De Filippo, Gianpaolo, D'Angelo, Giuseppina, Pensabene, Licia, Malamisura, Basilio, Cecere, Gaetano, Micillo, Maria, Francavilla, Ruggiero, Tetro, Anna, Lombardi, Giuliano, Tonelli, Lisa, Castellucci, Giuseppe, Ferraro, Luigi, Di Biase, Rita, Lezo, Antonella, Salvatore, Silvia, Paoletti, Silvia, Siani, Alfonso, Galeone, Daniela, Strazzullo, Pasquale

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Brief communication: Comparing hydrological and hydrogeomorphic paradigms for global flood hazard mapping by Di Baldassarre, Giuliano, Nardi, Fernando, Annis, Antonio, Odongo, Vincent, Rusca, Maria, Grimaldi, Salvatore

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Progressive myoclonus epilepsies—Residual unsolved cases have marked genetic heterogeneity including dolichol-dependent protein glycosylation pathway genes by Courage, Carolina, Oliver, Karen L., Park, Eon Joo, Cameron, Jillian M., Grabińska, Kariona A., Muona, Mikko, Canafoglia, Laura, Gambardella, Antonio, Said, Edith, Afawi, Zaid, Baykan, Betul, Brandt, Christian, di Bonaventura, Carlo, Chew, Hui Bein, Criscuolo, Chiara, Dibbens, Leanne M., Castellotti, Barbara, Riguzzi, Patrizia, Labate, Angelo, Filla, Alessandro, Giallonardo, Anna T., Berecki, Geza, Jackson, Christopher B., Joensuu, Tarja, Damiano, John A., Kivity, Sara, Korczyn, Amos, Palotie, Aarno, Striano, Pasquale, Uccellini, Davide, Giuliano, Loretta, Andermann, Eva, Scheffer, Ingrid E., Michelucci, Roberto, Bahlo, Melanie, Franceschetti, Silvana, Sessa, William C., Berkovic, Samuel F., Lehesjoki, Anna-Elina

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2-year outcomes of MitraClip as a bridge to heart transplantation: The international MitraBridge registry by Munafò, Andrea Raffaele, Scotti, Andrea, Estévez-Loureiro, Rodrigo, Adamo, Marianna, Hernàndez, Antonio Portolés, Peregrina, Estefanìa Fernàndez, Gutierrez, Lola, Taramasso, Maurizio, Fam, Neil P., Ho, Edwin C., Asgar, Anita, Vitrella, Giancarlo, Raineri, Claudia, Chizzola, Giuliano, Pezzola, Elisa, Le Ruz, Robin, Montalto, Claudio, Oreglia, Jacopo A., Fraccaro, Chiara, Giannini, Cristina, Fiorelli, Francesca, Rubbio, Antonio Popolo, Ooms, J.F., Compagnone, Miriam, Marcelli, Chiara, Maffeo, Diego, Bettari, Luca, Fürholz, Monika, Arzamendi, Dabit, Guerin, Patrice, Tamburino, Corrado, Petronio, A. Sonia, Grasso, Carmelo, Agricola, Eustachio, Van Mieghem, Nicolas M., Tarantini, Giuseppe, Praz, Fabien, Pascual, Isaac, Potena, Luciano, Colombo, Antonio, Maisano, Francesco, Metra, Marco, Margonato, Alberto, Crimi, Gabriele, Saia, Francesco, Godino, Cosmo

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Kufs disease due to mutation of CLN6: clinical, pathological and molecular genetic features by Berkovic, Samuel F, Oliver, Karen L, Canafoglia, Laura, Krieger, Penina, Damiano, John A, Hildebrand, Michael S, Morbin, Michela, Vears, Danya F, Sofia, Vito, Giuliano, Loretta, Garavaglia, Barbara, Simonati, Alessandro, Santorelli, Filippo M, Gambardella, Antonio, Labate, Angelo, Belcastro, Vincenzo, Castellotti, Barbara, Ozkara, Cigdem, Zeman, Adam, Rankin, Julia, Mole, Sara E, Aguglia, Umberto, Farrell, Michael, Rajagopalan, Sulekha, McDougall, Alan, Brammah, Susan, Andermann, Frederick, Andermann, Eva, Dahl, Hans-Henrik M, Franceschetti, Silvana, Carpenter, Stirling

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Blast-induced liquefaction in silty sands for full-scale testing of ground improvement methods: Insights from a multidisciplinary study by Amoroso, Sara, Rollins, Kyle M., Andersen, Paul, Gottardi, Guido, Tonni, Laura, García Martínez, Maria F., Wissmann, Kord, Minarelli, Luca, Comina, Cesare, Fontana, Daniela, De Martini, Paolo Marco, Monaco, Paola, Pesci, Arianna, Sapia, Vincenzo, Vassallo, Maurizio, Anzidei, Marco, Carpena, Andrea, Cinti, Francesca, Civico, Riccardo, Coco, Igino, Conforti, Dario, Doumaz, Fawzi, Giannattasio, Fabio, Di Giulio, Giuseppe, Foti, Sebastiano, Loddo, Fabiana, Lugli, Stefano, Manuel, Maria R., Marchetti, Diego, Mariotti, Mauro, Materni, Valerio, Metcalfe, Brian, Milana, Giuliano, Pantosti, Daniela, Pesce, Antonio, Salocchi, Aura C., Smedile, Alessandra, Stefani, Marco, Tarabusi, Gabriele, Teza, Giordano

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Declining Prevalence of HIV-1 Drug Resistance in Antiretroviral Treatment-exposed Individuals in Western Europe by De Luca, Andrea, Dunn, David, Zazzi, Maurizio, Camacho, Ricardo, Torti, Carlo, Fanti, Iuri, Kaiser, Rolf, Sönnerborg, Anders, Codoñer, Francisco M., Van Laethem, Kristel, Vandamme, Anne-Mieke, Bansi, Loveleen, Ghisetti, Valeria, van de Vijver, David A. M. C., Asboe, David, Prosperi, Mattia C. F., Di Giambenedetto, Simona

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Effects of Manidipine and Delapril in Hypertensive Patients With Type 2 Diabetes Mellitus: The Delapril and Manidipine for Nephroprotection in Diabetes (DEMAND) Randomized Clinical... by Ruggenenti, Piero, Lauria, Giuseppe, Iliev, Ilian Petrov, Fassi, Anna, Ilieva, Aneliya Parvanova, Rota, Stefano, Chiurchiu, Carlos, Barlovic, Drazenka Pongrac, Sghirlanzoni, Angelo, Lombardi, Raffaella, Penza, Paola, Cavaletti, Guido, Piatti, Maria Luisa, Frigeni, Barbara, Filipponi, Marco, Rubis, Nadia, Noris, Greta, Motterlini, Nicola, Ene-Iordache, Bogdan, Gaspari, Flavio, Perna, Annalisa, Zaletel, Jelka, Bossi, Antonio, Dodesini, Alessandro Roberto, Trevisan, Roberto, Remuzzi, Giuseppe

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Characterization and in silico Mutagenic Assessment of a New Betahistine Degradation Impurity by de Mello, Murilo, de Oliveira, Antonio, de Oliveira, Caroline, Ultramari, Mariah, Gama, Fernando, Mascarello, Alessandra, Guimarães, Cristiano, de Freitas, Miller, Cunha, Carlos, Lourenço, Tiago, Ferreira, Fernanda, Lopes, João, Clososki, Giuliano

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Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning by BOENGLER, Kerstin, DODONI, Giuliano, HEUSCH, Gerd, SCHULZ, Rainer, RODRIGUEZ-SINOVAS, Antonio, CABESTRERO, Alberto, RUIZ-MEANA, Marisol, GRES, Petra, KONIETZKA, Ina, LOPEZ-IGLESIAS, Carmen, GARCIA-DORADO, David, DI LISA, Fabio

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Saccharomyces cerevisiae and non-Saccharomyces yeasts in grape varieties of the São Francisco Valley by de Ponzzes-Gomes, Camila M P B S, de Mélo, Dângelly L F M, Santana, Caroline A, Pereira, Giuliano E, Mendonça, Michelle O C, Gomes, Fátima C O, Oliveira, Evelyn S, Barbosa, Jr, Antonio M, Trindade, Rita C, Rosa, Carlos A

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Production of fermented cheese whey-based beverage using kefir grains as starter culture: Evaluation of morphological and microbial variations by Magalhães, Karina Teixeira, Pereira, Maria Alcina, Nicolau, Ana, Dragone, Giuliano, Domingues, Lucília, Teixeira, José António, de Almeida Silva, João Batista, Schwan, Rosane Freitas

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