Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans by Izotova, Natalia, Rivat, Christine, Baricordi, Cristina, Blanco, Elena, Pellin, Danilo, Watt, Eleanor, Gkazi, Athina S., Adams, Stuart, Gilmour, Kimberly, Bayford, Jinhua, Booth, Claire, Gaspar, H. Bobby, Thrasher, Adrian J., Biasco, Luca

Get full text

The importance of taking ART appropriately in children and adolescents with HIV-1 to reach the highest capacity of immune function later in life by Sandgaard, Katrine Schou, Gkouleli, Triantafylia, Attenborough, Teresa, Adams, Stuart, Gibbons, Deena, Holm, Mette, Eisen, Sarah, Baxendale, Helen, De Rossi, Anita, Pahwa, Savita, Chain, Benny, Gkazi, Athina S, Klein, Nigel

Get full text

Plasticity of the Immune System in Children Following Treatment Interruption in HIV-1 Infection by Sandgaard, Katrine Schou, Margetts, Ben, Attenborough, Teresa, Gkouleli, Triantafylia, Adams, Stuart, Holm, Mette, Gibb, Diana, Gibbons, Deena, Giaquinto, Carlo, De Rossi, Anita, Bamford, Alasdair, Palma, Paolo, Chain, Benny, Gkazi, Athina S, Klein, Nigel

Get full text

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways by Cirulli, Elizabeth T., Lasseigne, Brittany N., Petrovski, Slavé, Sapp, Peter C., Dion, Patrick A., Leblond, Claire S., Couthouis, Julien, Lu, Yi-Fan, Wang, Quanli, Krueger, Brian J., Ren, Zhong, Keebler, Jonathan, Han, Yujun, Levy, Shawn E., Boone, Braden E., Wimbish, Jack R., Waite, Lindsay L., Jones, Angela L., Carulli, John P., Day-Williams, Aaron G., Staropoli, John F., Xin, Winnie W., Chesi, Alessandra, Raphael, Alya R., McKenna-Yasek, Diane, Cady, Janet, de Jong, J. M. B. Vianney, Kenna, Kevin P., Smith, Bradley N., Topp, Simon, Miller, Jack, Gkazi, Athina, Al-Chalabi, Ammar, van den Berg, Leonard H., Veldink, Jan, Silani, Vincenzo, Ticozzi, Nicola, Shaw, Christopher E., Baloh, Robert H., Appel, Stanley, Simpson, Ericka, Lagier-Tourenne, Clotilde, Pulst, Stefan M., Gibson, Summer, Trojanowski, John Q., Elman, Lauren, McCluskey, Leo, Grossman, Murray, Shneider, Neil A., Chung, Wendy K., Ravits, John M., Glass, Jonathan D., Sims, Katherine B., Van Deerlin, Vivianna M., Maniatis, Tom, Hayes, Sebastian D., Ordureau, Alban, Swarup, Sharan, Landers, John, Baas, Frank, Allen, Andrew S., Bedlack, Richard S., Harper, J. Wade, Gitler, Aaron D., Rouleau, Guy A., Brown, Robert, Harms, Matthew B., Cooper, Gregory M., Harris, Tim, Myers, Richard M., Goldstein, David B.

Get full text

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis by Dewan, Ramita, Keagle, Pamela, Bacikova, Dagmar, Soltis, Anthony R., Kost, Jason, Colombrita, Claudia, Lewis, Elizabeth A., Pensato, Viviana, Castellotti, Barbara, McLaughlin, Russell L., Comi, Giacomo P., Ceroni, Mauro, Gagliardi, Stella, van Blitterswijk, Marka, Corrado, Lucia, Sorarù, Gianni, Williams, Kelly L., Morrison, Karen E., Veldink, Jan H., Brown, Robert H., Ambrose, John C., Brittain, H., Elgar, Greg, Halai, Dina, Holman, James E., Jackson, Rob, Leong, Ivonne U.S., Maleady-Crowe, Fiona, Mason, Joanne, Riesgo-Ferreiro, Pablo, Rogers, Tim, Watters, Sarah A., Arepalli, Sampath, Chiò, Adriano, Dunckley, Travis L., Faghri, Faraz, Feldman, Eva, Floeter, Mary Kay, Gerhard, Glenn, Jansson, Lilja, Kirby, Janine, Mora, Gabriele, Nalls, Mike A., Pulst, Stefan M., Ravits, John M., Renton, Alan E., Robberecht, Wim, Robey, Ian, Dols-Icardo, Oriol, Illán-Gala, Ignacio, Lleó, Alberto, Khoshnood, Behzad, Sorbi, Sandro, Pastor, Pau, Bigio, Eileen H., Black, Sandra E., Brunetti, Maura, Canosa, Antonio, Gan-Or, Ziv, Goate, Alison, Hupalo, Daniel, Infante, Jon, Kaufmann, Horacio, Kim, Ronald C., Krüger, Rejko, Logroscino, Giancarlo, Love, Seth, Mao, Qinwen, Masliah, Eliezer, Pletnikova, Olga, Reynolds, Regina H., Scherzer, Clemens R., Serrano, Geidy E., Xiromerisiou, Georgia, Phatnani, Hemali, Kwan, Justin, Broach, James R., Arcila-Londono, Ximena, Malaspina, Andrea, Thompson, Leslie M., Dardiotis, Efthimios, Chandran, Siddharthan, Butovsky, Oleg, Dubnau, Joshua, Harms, Matt, Poss, Mary, Phillips-Cremins, Jennifer, Altschuler, Steven, Hu, Michele T.M., Leigh, P. Nigel, Massey, Luke A., Pavese, Nicola, Vaughan, Jenny, Rowe, James B., Ghidoni, Roberta, Ryten, Mina, Tanaka, Toshiko, Ferrucci, Luigi, Vonsattel, Jean Paul, Landers, John E.

Get full text

The CHCHD10 P34S variant is not associated with ALS in a UK cohort of familial and sporadic patients by Wong, Chun Hao, Topp, Simon, Gkazi, Athina Soragia, Troakes, Claire, Miller, Jack W, de Majo, Martina, Kirby, Janine, Shaw, Pamela J, Morrison, Karen E, de Belleroche, Jacqueline, Vance, Caroline A, Al-Chalabi, Ammar, Al-Sarraj, Safa, Shaw, Christopher E, Smith, Bradley N

Get full text

Base-edited CAR T cells for combinational therapy against T cell malignancies by Georgiadis, Christos, Rasaiyaah, Jane, Gkazi, Soragia Athina, Preece, Roland, Etuk, Aniekan, Christi, Abraham, Qasim, Waseem

Get full text

Clinically Applicable Assessment of Tisagenlecleucel CAR T Cell Treatment by Digital Droplet PCR for Copy Number Variant Assessment by Gkazi, Soragia Athina, Gravett, Emma, Bautista, Carla, Bartram, Jack, Ghorashian, Sara, Adams, Stuart Paul

Get full text

‘Mini’ U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects by Preece, Roland, Georgiadis, Christos, Gkazi, Soragia Athina, Etuk, Aniekan, Christi, Abraham, Qasim, Waseem

Get full text

Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options by Georgiadis, Christos, Nickolay, Lauren, Syed, Farhatullah, Zhan, Hong, Gkazi, Soragia Athina, Etuk, Annie, Abramowski-Mock, Ulrike, Preece, Roland, Cuber, Piotr, Adams, Stuart, Ottaviano, Giorgio, Qasim, Waseem

Get full text

Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy by Moretti, Federico A., Giardino, Giuliana, Attenborough, Teresa C. H., Gkazi, Athina Soragia, Margetts, Ben K., la Marca, Giancarlo, Fairbanks, Lynette, Crompton, Tessa, Gaspar, H. Bobby

Get full text

Routine Whole Genome Sequencing Offers a More Comprehensive Assessment of IG/TCR Gene Rearrangements for MRD Targets in Acute Lymphoblastic Leukemia - Data from the First 62 Cases... by Adams, Stuart, Hancock, Jeremy, Kaplinsky, Joe, Sosinsky, Alona, Wright, Gary, Gkazi, Soragia Athina, Kricke, Susanne, Thomas, Rebecca, Kent, Natalie, Hodder, Angus, Bartram, Jack

Get full text

Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation by Gkazi, Athina Soragia, Margetts, Ben K, Attenborough, Teresa, Mhaldien, Lana, Standing, Joseph F, Oakes, Theres, Heather, James M, Booth, John, Pasquet, Marlene, Chiesa, Robert, Veys, Paul, Klein, Nigel, Chain, Benny, Callard, Robin, Adams, Stuart P

Get full text

Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia by Ottaviano, Giorgio, Georgiadis, Christos, Gkazi, Soragia Athina, Syed, Farhatullah, Zhan, Hong, Etuk, Annie, Preece, Roland, Chu, Jan, Kubat, Agnieszka, Adams, Stuart, Veys, Paul, Vora, Ajay, Rao, Kanchan, Qasim, Waseem

Get full text

Author Correction: Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy by Moretti, Federico A., Giardino, Giuliana, Attenborough, Teresa C. H., Gkazi, Athina Soragia, Margetts, Ben K., la Marca, Giancarlo, Fairbanks, Lynette, Crompton, Tessa, Gaspar, H. Bobby

Get full text

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS by Kim, Hong Joo, Kim, Nam Chul, Wang, Yong-Dong, Scarborough, Emily A., Moore, Jennifer, Diaz, Zamia, MacLea, Kyle S., Freibaum, Brian, Li, Songqing, Molliex, Amandine, Kanagaraj, Anderson P., Carter, Robert, Boylan, Kevin B., Wojtas, Aleksandra M., Rademakers, Rosa, Pinkus, Jack L., Greenberg, Steven A., Trojanowski, John Q., Traynor, Bryan J., Smith, Bradley N., Topp, Simon, Gkazi, Athina-Soragia, Miller, Jack, Shaw, Christopher E., Kottlors, Michael, Kirschner, Janbernd, Pestronk, Alan, Li, Yun R., Ford, Alice Flynn, Gitler, Aaron D., Benatar, Michael, King, Oliver D., Kimonis, Virginia E., Ross, Eric D., Weihl, Conrad C., Shorter, James, Taylor, J. Paul

Get full text

Universal' Fratricide-Resistant CAR T Cells Against T Cell Leukemia Generated By Coupled & Uncoupled Deamination Mediated Base Editing by Georgiadis, Christos, Rasaiyaah, Jane, Gkazi, Soragia Athina, Preece, Roland, Etuk, Annie, Christi, Abraham, Qasim, Waseem

Get full text

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia by Williams, Kelly L., Topp, Simon, Yang, Shu, Smith, Bradley, Fifita, Jennifer A., Warraich, Sadaf T., Zhang, Katharine Y., Farrawell, Natalie, Vance, Caroline, Hu, Xun, Chesi, Alessandra, Leblond, Claire S., Lee, Albert, Rayner, Stephanie L., Sundaramoorthy, Vinod, Dobson-Stone, Carol, Molloy, Mark P., van Blitterswijk, Marka, Dickson, Dennis W., Petersen, Ronald C., Graff-Radford, Neill R., Boeve, Bradley F., Murray, Melissa E., Pottier, Cyril, Don, Emily, Winnick, Claire, McCann, Emily P., Hogan, Alison, Daoud, Hussein, Levert, Annie, Dion, Patrick A., Mitsui, Jun, Ishiura, Hiroyuki, Takahashi, Yuji, Goto, Jun, Kost, Jason, Gellera, Cinzia, Gkazi, Athina Soragia, Miller, Jack, Stockton, Joanne, Brooks, William S., Boundy, Karyn, Polak, Meraida, Muñoz-Blanco, José Luis, Esteban-Pérez, Jesús, Rábano, Alberto, Hardiman, Orla, Morrison, Karen E., Ticozzi, Nicola, Silani, Vincenzo, de Belleroche, Jacqueline, Glass, Jonathan D., Kwok, John B. J., Guillemin, Gilles J., Chung, Roger S., Tsuji, Shoji, Brown, Robert H., García-Redondo, Alberto, Rademakers, Rosa, Landers, John E., Gitler, Aaron D., Rouleau, Guy A., Cole, Nicholas J., Yerbury, Justin J., Atkin, Julie D., Shaw, Christopher E., Nicholson, Garth A., Blair, Ian P.

Get full text

Single and Combinational Multiplex Base-Edited 'Universal' CAR T Cells in a Humanised Model of Primary CD7+CD33+ AML by Kloos, Arnold, Georgiadis, Christos, Etuk, Annie, Gkazi, Soragia Athina, Syed, Farhatullah, Braybrook, Toni, Zhan, Hong, Kadirkamanathan, Renuka, Kattre, Nadine, Görlich, Kerstin, Fangmann, Thomas, Schambach, Axel, Sauer, Martin G., Heuser, Michael, Qasim, Waseem

Get full text

CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity by Preece, Roland, Pavesi, Andrea, Gkazi, Soragia Athina, Stegmann, Kerstin A., Georgiadis, Christos, Tan, Zhi Ming, Aw, Jia Ying Joey, Maini, Mala K., Bertoletti, Antonio, Qasim, Waseem

Get full text