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The NF-ĸB p50 subunit generated by KPC1-mediated ubiquitination and limited proteasomal processing, suppresses tumor growth
by
Kravtsova-Ivantsiv, Yelena
,
Goldhirsh, Gilad
,
Tomuleasa, Ciprian
,
Pikarsky, Eli
,
Ciechanover, Aaron
Published in
Cancer cell international
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A short binding site in the KPC1 ubiquitin ligase mediates processing of NF-κB1 p105 to p50: A potential for a tumor-suppressive PROTAC
by
Goldhirsh, Gilad
,
Kravtsova-Ivantsiv, Yelena
,
Satish, Gandhesiri
,
Ziv, Tamar
,
Brik, Ashraf
,
Ciechanover, Aaron
Published in
Proceedings of the National Academy of Sciences - PNAS
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Vimentin is a ubiquitination and degradation substrate of the ubiquitin ligase KPC1
by
Gottfried, Yossi
,
Lulu-Shimron, Chen
,
Goldhirsh, Gilad
,
Fisher, Yael
,
Ziv, Tamar
,
Hoon, Dave S.B.
,
Kravtsova-Ivantsiv, Yelena
,
Ciechanover, Aaron
Published in
Biochemical and biophysical research communications
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Inhibition of nucleo-cytoplasmic proteasome translocation by the aromatic amino acids or silencing Sestrin3—their sensing mediator—is tumor suppressive
by
Livneh, Ido
,
Fabre, Bertrand
,
Goldhirsh, Gilad
,
Lulu, Chen
,
Zinger, Adar
,
Shammai Vainer, Yael
,
Kaduri, Maya
,
Dahan, Aviva
,
Ziv, Tamar
,
Schroeder, Avi
,
Ben-Neriah, Yinon
,
Zohar, Yaniv
,
Cohen-Kaplan, Victoria
,
Ciechanover, Aaron
Published in
Cell death and differentiation
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Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1– and chemokines-mediated mechanisms
by
Kravtsova-Ivantsiv, Yelena
,
Goldhirsh, Gilad
,
Ivantsiv, Alexandra
,
Itzhak, Ofer Ben
,
Kwon, Yong Tae
,
Pikarsky, Eli
,
Ciechanover, Aaron
Published in
Proceedings of the National Academy of Sciences - PNAS
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Proceedings Of The National Academy Of Sciences - Pnas
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Biochemical And Biophysical Research Communications
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Cancer Cell International
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Cell Death And Differentiation
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Subjects
Apoptosis
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Cell Death
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Proteasomes
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Tumors
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Ubiquitin
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Amino Acids
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Cell Line, Tumor
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Cell Proliferation
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Humans
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Immune Response
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Kpc1
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Science & Technology
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Ubiquitin-Protein Ligase
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Ubiquitination
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Animal Models
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Biochemistry & Molecular Biology
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Ccl3 Protein
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