Paving the way towards an effective treatment for multiple sclerosis: advances in cell therapy by Mansilla, M. J., Presas-Rodríguez, S., Teniente-Serra, A., González-Larreategui, I., Quirant-Sánchez, B., Fondelli, F., Djedovic, N., Iwaszkiewicz-Grześ, D., Chwojnicki, K., Miljković, Đ., Trzonkowski, P., Ramo-Tello, C., Martínez-Cáceres, E. M.

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Characterization of KRAS-driven NSCLC cell lines with diverse mutational landscape and assessment of their response to MYC inhibition by González-Larreategui, Í., Vera, L., Giuntini, F., Martínez-Martín, S., Grueso, J., López, S., Serrano del Pozo, E., Thabussot, H., Macaya, I., Beaulieu, M.E., Vicent, S., Casacuberta-Serra, S., Soucek, L.

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217 (PB205): Therapeutic impact and reactivation of tumor immunity by MYC inhibition in KRAS-driven NSCLC with diverse mutational landscapes by González-Larreategui, I., Vera, L., Capitán-Leo, D., Sansegundo, L., Giuntini, F., Martínez-Martín, S., Thabussot, H., López-Estévez, S., del Pozo, E. Serrano, Grueso, J., Foradada, L., Macaya, I., Beaulieu, M.E., Vicent, S., Casacuberta-Serra, S., Soucek, L.

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Omomyc as a novel therapeutic strategy against metastatic triplenegative breast cancer, alone and in combination with the standard of care by Giuntini, F., Massó-Vallés, D., González-Larreategui, Í., Thabussot, H., Kaur, J., Zacarías-Fluck, M., Casacuberta-Serra, S., Martínez-Martín, S., Foradada-Felip, L., Serrano, E., Martín-Fernández, G., Castillo Cano, V., López-Estévez, S., Serra, V., Whitfield, J., Beaulieu, M.E., Soucek, L.

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213 (PB201): MYC Inhibition by OMO-103 Reprograms Tumor Immunity and Enhances Immunotherapy Efficacy in KRAS Mutant NSCLC by Serra, S. Casacuberta, González-Larreategui, I., Vera, L., Adradas, V., Martínez-Martín, S., Peressini, M., López-Estévez, S., Arnal, M., Sansegundo, L., del Pozo, E. Serrano, Grueso, J., Foradada, L., Thabussot, H., Giuntini, F., Whitfield, J., Beaulieu, M.E., Zugazagoitia, J., Vicent, S., Soucek, L.

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Omomyc downregulates MYC transcriptional signature in preclinical models of solid tumours and shows long half-life in tumour tissue by Martínez Martín, S., López-Estévez, S., Foradada, L., Kaur, J., Serrano, E., González-Larreategui, Í., Giuntini, F., Casacuberta-Serra, S., Thabussot, H., Castillo Cano, V., Nonell, L., Soucek, L., Beaulieu, M.E.

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MYC inhibition by OMO-103 induces immune cell recruitment in preclinical models of NSCLC and modulates the cytokine and chemokine profiles of Phase I patients showing stable diseas... by Casacuberta Serra, S., Martínez-Martín, S., González-Larreategui, Í., López-Estévez, S., Jauset, T., Zacarías-Fluck, M., Massó-Vallés, D., Martín, G., Foradada, L., Grueso, J., Serrano, E., Thabussot, H., Castillo Cano, V., Whitfield, J.R., Morales, J., Niewel, M., Beaulieu, M.E., Soucek, L.

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MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer by Casacuberta-Serra, Sílvia, González-Larreategui, Íñigo, Capitán-Leo, Daniel, Soucek, Laura

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Transfection of Vitamin D3-Induced Tolerogenic Dendritic Cells for the Silencing of Potential Tolerogenic Genes. Identification of CSF1R-CSF1 Signaling as a Glycolytic Regulator by Mansilla, María José, González-Larreategui, Iñigo, Figa-Martín, Neus, Barallat, Jaume, Fondelli, Federico, Sellés-Rius, Ares, Quirant-Sánchez, Bibiana, Teniente-Serra, Aina, Martínez-Cáceres, Eva

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eIF4A dependency: the hidden key to unlock KRAS mutant non-small cell lung cancer’s vulnerability by Casacuberta-Serra, Silvia, Gonzalez-Larreategui, Iñigo, Soucek, Laura

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Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma by Zacarías-Fluck, Mariano F, Massó-Vallés, Daniel, Giuntini, Fabio, González-Larreategui, Íñigo, Kaur, Jastrinjan, Casacuberta-Serra, Sílvia, Jauset, Toni, Martínez-Martín, Sandra, Martín-Fernández, Génesis, Serrano Del Pozo, Erika, Foradada, Laia, Grueso, Judit, Nonell, Lara, Beaulieu, Marie-Eve, Whitfield, Jonathan R, Soucek, Laura

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The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets by Zacarías-Fluck, Mariano F, Jauset, Toni, Martínez-Martín, Sandra, Kaur, Jastrinjan, Casacuberta-Serra, Sílvia, Massó-Vallés, Daniel, Serrano Del Pozo, Erika, Martín-Fernández, Génesis, González-Larreategui, Íñigo, López-Estévez, Sergio, Brown-Swigart, Lamorna, Beaulieu, Marie-Eve, Whitfield, Jonathan R, Madan, Babita, Virshup, David M, Evan, Gerard I, Soucek, Laura

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Abstract 3435: Identification of potential biomarkers of response to OMO-103, a first-in-modality pan-MYC inhibitor, in patients with advanced solid tumors by Beaulieu, Marie-Eve, Garralda, Elena, Casacuberta-Serra, Sílvia, Martínez-Martín, Sandra Sandra, Calvo, Emiliano, Moreno, Víctor, López-Estévez, Sergio, Foradada, Laia, Alonso, Guzman, Corral, Elena, Doger, Bernard, Hernández, Tatiana, Grueso, Judit, González-Larreategui, Íñigo Íñigo, Pozo, Erika Serrano del, Thabussot, Hugo, Cano, Virginia Castillo, Zacarías-Fluck, Mariano F. Mariano F., Kaur, Jastrinjan, Giuntini, Fabio, Whitfield, Jonathan R., Morales, Josefa, Niewel, Manuela, Soucek, Laura

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