A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma by Hayes, Tikvah K, Luo, Flora, Cohen, Ofir, Goodale, Amy B, Lee, Yenarae, Pantel, Sasha, Bagul, Mukta, Piccioni, Federica, Root, David E, Garraway, Levi A, Meyerson, Matthew, Johannessen, Cory M

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Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants by Hayes, Tikvah K., Aquilanti, Elisa, Persky, Nicole S., Yang, Xiaoping, Kim, Erica E., Brenan, Lisa, Goodale, Amy B., Alan, Douglas, Sharpe, Ted, Shue, Robert E., Westlake, Lindsay, Golomb, Lior, Silverman, Brianna R., Morris, Myshal D., Fisher, Ty Running, Beyene, Eden, Li, Yvonne Y., Cherniack, Andrew D., Piccioni, Federica, Hicks, J. Kevin, Chi, Andrew S., Cahill, Daniel P., Dietrich, Jorg, Batchelor, Tracy T., Root, David E., Johannessen, Cory M., Meyerson, Matthew

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Author Correction: Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants by Hayes, Tikvah K., Aquilanti, Elisa, Persky, Nicole S., Yang, Xiaoping, Kim, Erica E., Brenan, Lisa, Goodale, Amy B., Alan, Douglas, Sharpe, Ted, Shue, Robert E., Westlake, Lindsay, Golomb, Lior, Silverman, Brianna R., Morris, Myshal D., Fisher, Ty Running, Beyene, Eden, Li, Yvonne Y., Cherniack, Andrew D., Piccioni, Federica, Hicks, J. Kevin, Chi, Andrew S., Cahill, Daniel P., Dietrich, Jorg, Batchelor, Tracy T., Root, David E., Johannessen, Cory M., Meyerson, Matthew

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A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering by To, Tsz-Leung, Cuadros, Alejandro M., Shah, Hardik, Hung, Wendy H.W., Li, Yang, Kim, Sharon H., Rubin, Daniel H.F., Boe, Ryan H., Rath, Sneha, Eaton, John K., Piccioni, Federica, Goodale, Amy, Kalani, Zohra, Doench, John G., Root, David E., Schreiber, Stuart L., Vafai, Scott B., Mootha, Vamsi K.

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Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting by Aguirre, Andrew J, Meyers, Robin M, Weir, Barbara A, Vazquez, Francisca, Zhang, Cheng-Zhong, Ben-David, Uri, Cook, April, Ha, Gavin, Harrington, William F, Doshi, Mihir B, Kost-Alimova, Maria, Gill, Stanley, Xu, Han, Ali, Levi D, Jiang, Guozhi, Pantel, Sasha, Lee, Yenarae, Goodale, Amy, Cherniack, Andrew D, Oh, Coyin, Kryukov, Gregory, Cowley, Glenn S, Garraway, Levi A, Stegmaier, Kimberly, Roberts, Charles W, Golub, Todd R, Meyerson, Matthew, Root, David E, Tsherniak, Aviad, Hahn, William C

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Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors by Malone, Clare F, Kim, Minjee, Alexe, Gabriela, Engel, Kathleen, Forman, Alexandra B, Robichaud, Amanda, Conway, Amy Saur, Goodale, Amy, Meyer, Ashleigh, Khalid, Delan, Thayakumar, Allen, Hatcher, John M, Gray, Nathanael S, Piccioni, Federica, Stegmaier, Kimberly

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Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma by Bandopadhayay, Pratiti, Piccioni, Federica, O’Rourke, Ryan, Ho, Patricia, Gonzalez, Elizabeth M., Buchan, Graham, Qian, Kenin, Gionet, Gabrielle, Girard, Emily, Coxon, Margo, Rees, Matthew G., Brenan, Lisa, Dubois, Frank, Shapira, Ofer, Greenwald, Noah F., Pages, Melanie, Balboni Iniguez, Amanda, Paolella, Brenton R., Meng, Alice, Sinai, Claire, Roti, Giovanni, Dharia, Neekesh V., Creech, Amanda, Tanenbaum, Benjamin, Khadka, Prasidda, Tracy, Adam, Tiv, Hong L., Hong, Andrew L., Coy, Shannon, Rashid, Rumana, Lin, Jia-Ren, Cowley, Glenn S., Lam, Fred C., Goodale, Amy, Lee, Yenarae, Schoolcraft, Kathleen, Vazquez, Francisca, Hahn, William C., Tsherniak, Aviad, Bradner, James E., Yaffe, Michael B., Milde, Till, Pfister, Stefan M., Qi, Jun, Schenone, Monica, Carr, Steven A., Ligon, Keith L., Kieran, Mark W., Santagata, Sandro, Olson, James M., Gokhale, Prafulla C., Jaffe, Jacob D., Root, David E., Stegmaier, Kimberly, Johannessen, Cory M., Beroukhim, Rameen

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LGG-45. Genetic dependencies inMYB/MYBL1-driven pediatric low-grade glioma models by Condurat, Alexandra-Larisa, Jones, Jill, Gonzalez, Elizabeth, Doshi, Jeyna, Zhou, Kevin, Tsai, Jessica W, Khadka, Prasidda, Buchan, Graham B J, Rouleau, Cecile, Pelton, Kristine, Abid, Tanaz, Goodale, Amy, Persky, Nicole, Beroukhim, Rameen, Ligon, Keith, Root, David, Piccioni, Federica, Bandopadhayay, Pratiti

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LGG-45. Genetic dependencies in MYB/MYBL1 -driven pediatric low-grade glioma models by Condurat, Alexandra-Larisa, Jones, Jill, Gonzalez, Elizabeth, Doshi, Jeyna, Zhou, Kevin, Tsai, Jessica W, Khadka, Prasidda, Buchan, Graham B J, Rouleau, Cecile, Pelton, Kristine, Abid, Tanaz, Goodale, Amy, Persky, Nicole, Beroukhim, Rameen, Ligon, Keith, Root, David, Piccioni, Federica, Bandopadhayay, Pratiti

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Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer by Stover, Elizabeth H, Baco, Maria B, Cohen, Ofir, Li, Yvonne Y, Christie, Elizabeth L, Bagul, Mukta, Goodale, Amy, Lee, Yenarae, Pantel, Sasha, Rees, Matthew G, Wei, Guo, Presser, Adam G, Gelbard, Maya K, Zhang, Weiqun, Zervantonakis, Ioannis K, Bhola, Patrick D, Ryan, Jeremy, Guerriero, Jennifer L, Montero, Joan, Liang, Felice J, Cherniack, Andrew D, Piccioni, Federica, Matulonis, Ursula A, Bowtell, David D L, Sarosiek, Kristopher A, Letai, Anthony, Garraway, Levi A, Johannessen, Cory M, Meyerson, Matthew

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Abstract 2010: Transcriptional antagonism by CDK8 inhibition improves therapeutic efficacy of MEK inhibitors by Malone, Clare F., Kim, Minjee, Alexe, Gabriela, Forman, Alexandra B., Robichaud, Amanda, Conway, Amy Saur, Goodale, Amy, Hatcher, John M., Gray, Nathanael S., Piccioni, Federica, Stegmaier, Kimberly

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Abstract AP14: POOLED GENOMIC SCREENS IDENTIFY ANTI-APOPTOTIC GENES AS MEDIATORS OF CHEMOTHERAPY RESISTANCE IN OVARIAN CANCER by Stover, Elizabeth H., Baco, Maria B., Cohen, Ofir, Li, Yvonne, Christie, Elizabeth, Bagul, Mukta, Goodale, Amy, Lee, Yenarae, Pantel, Sasha, Rees, Matthew, Wei, Guo, Presser, Adam, Zervantonakis, Ioannis, Bhola, Patrick, Ryan, Jeremy, Guerriero, Jennifer, Liang, Felice, Cherniack, Andrew, Piccioni, Federica, Matulonis, Ursula A., Bowtell, David D. L., Letai, Anthony, Sarosiek, Kris, Garraway, Levi, Johannessen, Cory M., Meyerson, Matthew

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Morphological map of under- and over-expression of genes in human cells by Chandrasekaran, Srinivas Niranj, Alix, Eric, Arevalo, John, Borowa, Adriana, Byrne, Patrick J, Charles, William G, Chen, Zitong S, Cimini, Beth A, Deng, Boxiong, Doench, John G, Ewald, Jessica D, Fritchman, Briana, Fuller, Colin J, Gaetz, Jedidiah, Goodale, Amy, Haghighi, Marzieh, Han, Yu, Hanifehlou, Zahra, Hennig, Holger, Hernandez, Desiree, Jacob, Christina B, James, Tim, Jetka, Tomasz, Kalinin, Alexandr A, Komalo, Ben, Kost-Alimova, Maria, Krawiec, Tomasz, Marion, Brittany A, Glynn, Martin, Mccarthy, Nicola J, Miller, Lisa, Monsees, Arne, Moshkov, Nikita, Muñoz, Alán F, Ogier, Arnaud, Otrocka, Magdalena, Rataj, Krzysztof, Root, David E, Rubbo, Francesco, Scrace, Simon F, Selinger, Douglas W, Senft, Rebecca A, Sommer, Peter, Thibaudeau, Amandine, Trisorus, Sarah, Veettil, Rahul Valiya, Van Trump, William J, Wang, Sui, Warchoł, Michał, Weisbart, Erin, Weiss, Amélie, Wiest, Michael, Zaremba, Agata, Zinovyev, Andrei, Singh, Shantanu, Carpenter, Anne E

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Optimizing the Cell Painting assay for image-based profiling by Cimini, Beth A, Chandrasekaran, Srinivas Niranj, Kost-Alimova, Maria, Miller, Lisa, Goodale, Amy, Fritchman, Briana, Byrne, Patrick, Garg, Sakshi, Jamali, Nasim, Logan, David J, Concannon, John B, Charles-Hugues Lardeau, Mouchet, Elizabeth, Singh, Shantanu, Abbasi, Hamdah Shafqat, Aspesi, Peter, Boyd, Justin D, Gilbert, Tamara, Gnutt, David, Hariharan, Santosh, Hernandez, Desiree, Hormel, Gisela, Juhani, Karolina, Melanson, Michelle, Lewis, Mervin, Monteverde, Tiziana, Pilling, James E, Skepner, Adam, Swalley, Susanne E, Vrcic, Anita, Weisbart, Erin, Williams, Guy, Yu, Shan, Bolek Zapiec, Carpenter, Anne E

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