The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer by Joseph, James D, Darimont, Beatrice, Zhou, Wei, Arrazate, Alfonso, Young, Amy, Ingalla, Ellen, Walter, Kimberly, Blake, Robert A, Nonomiya, Jim, Guan, Zhengyu, Kategaya, Lorna, Govek, Steven P, Lai, Andiliy G, Kahraman, Mehmet, Brigham, Dan, Sensintaffar, John, Lu, Nhin, Shao, Gang, Qian, Jing, Grillot, Kate, Moon, Michael, Prudente, Rene, Bischoff, Eric, Lee, Kyoung-Jin, Bonnefous, Celine, Douglas, Karensa L, Julien, Jackaline D, Nagasawa, Johnny Y, Aparicio, Anna, Kaufman, Josh, Haley, Benjamin, Giltnane, Jennifer M, Wertz, Ingrid E, Lackner, Mark R, Nannini, Michelle A, Sampath, Deepak, Schwarz, Luis, Manning, Henry Charles, Tantawy, Mohammed Noor, Arteaga, Carlos L, Heyman, Richard A, Rix, Peter J, Friedman, Lori, Smith, Nicholas D, Metcalfe, Ciara, Hager, Jeffrey H

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Maximizing ER‑α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927 by Kahraman, Mehmet, Govek, Steven P, Nagasawa, Johnny Y, Lai, Andiliy, Bonnefous, Celine, Douglas, Karensa, Sensintaffar, John, Liu, Nhin, Lee, KyoungJin, Aparicio, Anna, Kaufman, Josh, Qian, Jing, Shao, Gang, Prudente, Rene, Joseph, James D, Darimont, Beatrice, Brigham, Daniel, Heyman, Richard, Rix, Peter J, Hager, Jeffrey H, Smith, Nicholas D

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Water-soluble PDE4 inhibitors for the treatment of dry eye by Govek, Steven P., Oshiro, Guy, Anzola, John V., Beauregard, Clay, Chen, Jasmine, Coyle, Avery R., Gamache, Daniel A., Hellberg, Mark R., Hsien, Jennifer N., Lerch, Julia M., Liao, John C., Malecha, James W., Staszewski, Lena M., Thomas, David J., Yanni, John M., Noble, Stewart A., Shiau, Andrew K.

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Optimization of an indazole series of selective estrogen receptor degraders: Tumor regression in a tamoxifen-resistant breast cancer xenograft by Govek, Steven P., Nagasawa, Johnny Y., Douglas, Karensa L., Lai, Andiliy G., Kahraman, Mehmet, Bonnefous, Celine, Aparicio, Anna M., Darimont, Beatrice D., Grillot, Katherine L., Joseph, James D., Kaufman, Joshua A., Lee, Kyoung-Jin, Lu, Nhin, Moon, Michael J., Prudente, Rene Y., Sensintaffar, John, Rix, Peter J., Hager, Jeffrey H., Smith, Nicholas D.

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Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen-resistant breast cancer xenograft by Govek, Steven P., Bonnefous, Celine, Julien, Jackaline D., Nagasawa, Johnny Y., Kahraman, Mehmet, Lai, Andiliy G., Douglas, Karensa L., Aparicio, Anna M., Darimont, Beatrice D., Grillot, Katherine L., Joseph, James D., Kaufman, Joshua A., Lee, Kyoung-Jin, Lu, Nhin, Moon, Michael J., Prudente, Rene Y., Sensintaffar, John, Rix, Peter J., Hager, Jeffrey H., Smith, Nicholas D.

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Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer by Joseph, James D, Darimont, Beatrice, Zhou, Wei, Arrazate, Alfonso, Young, Amy, Ingalla, Ellen, Walter, Kimberly, Blake, Robert A, Nonomiya, Jim, Guan, Zhengyu, Kategaya, Lorna, Govek, Steven P, Lai, Andiliy G, Kahraman, Mehmet, Brigham, Dan, Sensintaffar, John, Lu, Nhin, Shao, Gang, Qian, Jing, Grillot, Kate, Moon, Michael, Prudente, Rene, Bischoff, Eric, Lee, Kyoung-Jin, Bonnefous, Celine, Douglas, Karensa L, Julien, Jackaline D, Nagasawa, Johnny Y, Aparicio, Anna, Kaufman, Josh, Haley, Benjamin, Giltnane, Jennifer M, Wertz, Ingrid E, Lackner, Mark R, Nannini, Michelle A, Sampath, Deepak, Schwarz, Luis, Manning, Henry Charles, Tantawy, Mohammed Noor, Arteaga, Carlos L, Heyman, Richard A, Rix, Peter J, Friedman, Lori, Smith, Nicholas D, Metcalfe, Ciara, Hager, Jeffrey H

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Total Synthesis of Asperazine by Govek, Steven P, Overman, Larry E

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Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Studies of Intramolecular Heck Reactions of (Z)-α,β-Unsaturated Anilides and Mechanistic Investigations of... by Ashimori, Atsuyuki, Bachand, Benoit, Calter, Michael A, Govek, Steven P, Overman, Larry E, Poon, Daniel J

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Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): Efficacy in an animal model for schizophrenia by Govek, Steven P., Bonnefous, Celine, Hutchinson, John H., Kamenecka, Theodore, McQuiston, Jeffrey, Pracitto, Richard, Zhao, Lucy X., Gardner, Michael F., James, Joyce K., Daggett, Lorrie P., Rowe, Blake A., Schaffhauser, Hervé, Bristow, Linda J., Campbell, Una C., Rodriguez, Dana E., Vernier, Jean-Michel

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Total synthesis of (+)-asperazine by Govek, Steven P., Overman, Larry E.

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Abstract 1648: Discovery and evolution of orally bioavailable selective estrogen receptor degraders for ER+ breast cancer: From GDC-0810 to GDC-0927 by Kahraman, Mehmet, Govek, Steven P., Nagasawa, Johnny Y., Lai, Andiliy, Bonnefous, Celine, Douglas, Karensa, Sensintaffar, John, Lu, Nhin, Lee, KyoungJin, Aparicio, Anna, Kaufman, Josh, Qian, Jing, Shao, Gang, Prudente, Rene, Joseph, James D., Darimont, Beatrice, Brigham, Daniel, Heyman, Richard, Rix, Peter J., Hager, Jeffrey H., Smith, Nicholas D., Blake, Robert A., Chang, Jae, Choo, Edna, Daemen, Anneleen, Friedman, Lori S., Guan, Jane, Hartman, Steven, Ingalla, Ellen, Kiefer, James R., Kleinheinz, Tracy, Labadie, Sharada, Metcalfe, Ciara, Mody, Vidhi, Nannini, Michelle, Sampath, Deepak, Young, Amy, Vinogradova, Maia, Zhou, Wei, Liang, Jun, Wang, Xiaojing

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