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Phosphorylation of Isolated Human Phosphodiesterase-5 Regulatory Domain Induces an Apparent Conformational Change and Increases cGMP Binding Affinity
by
Francis, Sharron H.
,
Bessay, Emmanuel P.
,
Kotera, Jun
,
Grimes, Kennard A.
,
Liu, Li
,
Thompson, W. Joseph
,
Corbin, Jackie D.
Published in
The Journal of biological chemistry
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Phosphorylation Increases Affinity of the Phosphodiesterase-5 Catalytic Site for Tadalafil
by
Bessay, Emmanuel P
,
Blount, Mitsi A
,
Zoraghi, Roya
,
Beasley, Alfreda
,
Grimes, Kennard A
,
Francis, Sharron H
,
Corbin, Jackie D
Published in
The Journal of pharmacology and experimental therapeutics
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cGMP-dependent protein kinase protects cGMP from hydrolysis by phosphodiesterase-5
by
Kotera, Jun
,
Grimes, Kennard A
,
Corbin, Jackie D
,
Francis, Sharron H
Published in
Biochemical journal
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Expression of an Active, Monomeric Catalytic Domain of the cGMP-binding cGMP-specific Phosphodiesterase (PDE5)
by
Fink, T L
,
Francis, S H
,
Beasley, A
,
Grimes, K A
,
Corbin, J D
Published in
The Journal of biological chemistry
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Activation by Cyclic GMP Binding Causes an Apparent Conformational Change in cGMP-dependent Protein Kinase
by
Chu, Der-Ming
,
Corbin, Jackie D.
,
Grimes, Kennard A.
,
Francis, Sharron H.
Published in
The Journal of biological chemistry
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Histidine-607 and Histidine-643 Provide Important Interactions for Metal Support of Catalysis in Phosphodiesterase-5
by
Francis, Sharron H
,
Turko, Illarion V
,
Grimes, Kennard A
,
Corbin, Jackie D
Published in
Biochemistry (Easton)
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Mechanisms Associated with cGMP Binding and Activation of cGMP-Dependent Protein Kinase
by
Wall, Michael E.
,
Francis, Sharron H.
,
Corbin, Jackie D.
,
Grimes, Kennard
,
Richie-Jannetta, Robyn
,
Kotera, Jun
,
Macdonald, Brian A.
,
Gibson, Rowena R.
,
Trewhella, Jill
Published in
Proceedings of the National Academy of Sciences - PNAS
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Sildenafil citrate does not affect cardiac contractility in human or dog heart
by
Corbin, Jackie
,
Rannels, Stephen
,
Neal, Doss
,
Chang, Paul
,
Grimes, Kennard
,
Beasley, Alfreda
,
Francis, Sharron
Published in
Current medical research and opinion
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Distinguishing the Roles of the Two Different cGMP-binding Sites for Modulating Phosphorylation of Exogenous Substrate (Heterophosphorylation) and Autophosphorylation of cGMP-depen...
by
Smith, J A
,
Reed, R B
,
Francis, S H
,
Grimes, K
,
Corbin, J D
Published in
The Journal of biological chemistry
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Ligand-Induced Conformational Changes in Cyclic Nucleotide Phosphodiesterases and Cyclic Nucleotide-Dependent Protein Kinases
by
Francis, Sharron H.
,
Chu, Der-Ming
,
Thomas, Melissa K.
,
Beasley, Alfreda
,
Grimes, Kennard
,
Busch, Jennifer L.
,
Turko, Illarion V.
,
Haik, Tamara L.
,
Corbin, Jackie D.
Published in
Methods (San Diego, Calif.)
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Arginine 75 in the Pseudosubstrate Sequence of Type Iβ cGMPdependent Protein Kinase Is Critical for Autoinhibition, Although Autophosphorylated Serine 63 Is Outside This Sequence
by
Francis, Sharron H.
,
Smith, Jeffrey A.
,
Colbran, Janet L.
,
Grimes, Kennard
,
Walsh, Kenneth A.
,
Kumar, Santosh
,
Corbin, Jackie D.
Published in
The Journal of biological chemistry
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Arginine 75 in the Pseudosubstrate Sequence of Type Iβ cGMPdependent Protein Kinase Is Critical for Autoinhibition, Although Autophosphorylated Serine 63 Is Outside This Sequence...
by
Sharron H. Francis
,
Jeffrey A. Smith
,
Janet L. Colbran
,
Kennard Grimes
,
Kenneth A. Walsh
,
Santosh Kumar
,
Jackie D. Corbin
Published in
The Journal of biological chemistry
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