Actionable Predictions of Human Pharmacokinetics at the Drug Design Stage by Komissarov, Leonid, Manevski, Nenad, Groebke Zbinden, Katrin, Schindler, Torsten, Zitnik, Marinka, Sach-Peltason, Lisa

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Computational Predictions of Nonclinical Pharmacokinetics at the Drug Design Stage by Stoyanova, Raya, Katzberger, Paul Maximilian, Komissarov, Leonid, Khadhraoui, Aous, Sach-Peltason, Lisa, Groebke Zbinden, Katrin, Schindler, Torsten, Manevski, Nenad

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TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity by Revel, Florent G, Moreau, Jean-Luc, Gainetdinov, Raul R, Bradaia, Amyaouch, Sotnikova, Tatyana D, Mory, Roland, Durkin, Sean, Zbinden, Katrin Groebke, Norcross, Roger, Meyer, Claas A, Metzler, Veit, Chaboz, Sylvie, Ozmen, Laurence, Trube, Gerhard, Pouzet, Bruno, Bettler, Bernhard, Caron, Marc G, Wettstein, Joseph G, Hoener, Marius C

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Trace Amine-Associated Receptor 1 Partial Agonism Reveals Novel Paradigm for Neuropsychiatric Therapeutics by Revel, Florent G, Moreau, Jean-Luc, Gainetdinov, Raul R, Ferragud, Antonio, Velázquez-Sánchez, Clara, Sotnikova, Tatyana D, Morairty, Stephen R, Harmeier, Anja, Groebke Zbinden, Katrin, Norcross, Roger D, Bradaia, Amyaouch, Kilduff, Thomas S, Biemans, Barbara, Pouzet, Bruno, Caron, Marc G, Canales, Juan J, Wallace, Tanya L, Wettstein, Joseph G, Hoener, Marius C

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Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity by Zbinden, Katrin Groebke, Banner, David W., Hilpert, Kurt, Himber, Jacques, Lavé, Thierry, Riederer, Markus A., Stahl, Martin, Tschopp, Thomas B., Obst-Sander, Ulrike

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Discovery of a factor Xa inhibitor (3 R,4 R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-pheny... by Anselm, Lilli, Banner, David W., Benz, Jörg, Groebke Zbinden, Katrin, Himber, Jacques, Hilpert, Hans, Huber, Walter, Kuhn, Bernd, Mary, Jean-Luc, Otteneder, Michael B., Panday, Narendra, Ricklin, Fabienne, Stahl, Martin, Thomi, Stefan, Haap, Wolfgang

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Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors by Zbinden, Katrin Groebke, Obst-Sander, Ulrike, Hilpert, Kurt, Kühne, Holger, Banner, David W., Böhm, Hans-Joachim, Stahl, Martin, Ackermann, Jean, Alig, Leo, Weber, Lutz, Wessel, Hans Peter, Riederer, Markus A., Tschopp, Thomas B., Lavé, Thierry

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Discovery and Characterization of 2‑Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists by Galley, Guido, Beurier, Angélica, Décoret, Guillaume, Goergler, Annick, Hutter, Roman, Mohr, Susanne, Pähler, Axel, Schmid, Philipp, Türck, Dietrich, Unger, Robert, Zbinden, Katrin Groebke, Hoener, Marius C, Norcross, Roger D

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Design of novel aminopyrrolidine factor Xa inhibitors from a screening hit by Zbinden, Katrin Groebke, Anselm, Lilli, Banner, David W., Benz, Jörg, Blasco, Francesca, Décoret, Guillaume, Himber, Jacques, Kuhn, Bernd, Panday, Narendra, Ricklin, Fabienne, Risch, Philippe, Schlatter, Daniel, Stahl, Martin, Thomi, Stefan, Unger, Robert, Haap, Wolfgang

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Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors by Groebke Zbinden, Katrin, Banner, David W., Ackermann, Jean, D’Arcy, Allan, Kirchhofer, Daniel, Ji, Yu-Hua, Tschopp, Thomas B., Wallbaum, Sabine, Weber, Lutz

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Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]... by Anselm, Lilli, Banner, David W, Benz, Jörg, Zbinden, Katrin Groebke, Himber, Jacques, Hilpert, Hans, Huber, Walter, Kuhn, Bernd, Mary, Jean-Luc, Otteneder, Michael B, Panday, Narendra, Ricklin, Fabienne, Stahl, Martin, Thomi, Stefan, Haap, Wolfgang

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