AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts by Byth, Kate F, Thomas, Andrew, Hughes, Gareth, Forder, Cheryl, McGregor, Alexandra, Geh, Catherine, Oakes, Sandra, Green, Clive, Walker, Mike, Newcombe, Nicholas, Green, Stephen, Growcott, Jim, Barker, Andy, Wilkinson, Robert W

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Preclinical evaluation of M30 and M65 ELISAs as biomarkers of drug induced tumor cell death and antitumor activity by Cummings, Jeffrey, Hodgkinson, Cassandra, Odedra, Rajesh, Sini, Patrizia, Heaton, Simon P, Mundt, Kirsten E, Ward, Tim H, Wilkinson, Robert W, Growcott, Jim, Hughes, Andrew, Dive, Caroline

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A Pilot Study Assessing the Prognostic Value of CK18 and nDNA Biomarkers in Severe Sepsis Patients by Moore, David J., Greystoke, Alastair, Butt, Fouziah, Wurthner, Jens, Growcott, Jim, Hughes, Andrew, Dive, Caroline

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A phase I pharmacodynamic study of the effects of the cyclin-dependent kinase-inhibitor AZD5438 on cell cycle markers within the buccal mucosa, plucked scalp hairs and peripheral b... by CAMIDGE, D. Ross, PEMBERTON, Mike, GROWCOTT, Jim, AMAKYE, Dereck, WILSON, David, SWAISLAND, Helen, FORDER, Cheryl, WILKINSON, Robert, BYTH, Kate, HUGHES, Andrew

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Quantification of skeletal metastases in castrate‐resistant prostate cancer predicts progression‐free and overall survival by Tait, Campbell, Moore, David, Hodgson, Clare, Brown, Michael, Morris, Thomas, Growcott, Jim, Malone, Michael, Hughes, Andrew, Renehan, Andrew, Clarke, Noel W., Dive, Caroline

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Abstract C9: Utility of serological apoptosis biomarkers: Assessment in a phase II study of zibotentan (ZD4054) in patients with hormone-resistant prostate cancer by Malone, Mike, Mann, Helen, Growcott, Jim, Butt, Fouziah, Moore, David

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Abstract 3890: Induction of cell cycle arrest and apoptosis in mantle cell lymphoma by AZD5438, a novel cyclin-dependent kinase inhibitor by Lo, Wann-Cheng, Growcott, Jim, LeBrun, David P., Greer, Peter A.

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Abstract 3848: Preclinical profile of AZD3514: A small molecule-targeting androgen receptor function with a novel mechanism of action and the potential to treat castration-resistan... by Loddick, Sarah A., Bradbury, Rob, Broadbent, Nicola, Campbell, Hayley, Gaughan, Luke, Growcott, Jim, Stratton, Natalie, Mouchet, Elizabeth, O'Neill, Daniel, Rabow, Al, Robinson, David, Robson, Craig N., Ross, Sarah J., Shaheen, Fadhel, Trueman, Dawn, Walker, Graeme, Wedge, Stephen R., Brooks, Nigel A.N.

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Abstract B107: Characterization of a small molecule selective androgen receptor downregulator: A novel approach for the treatment of castration-resistant prostate cancer by Loddick, Sarah A., Brave, Sandra, Campbell, Hayley, Gaughan, Luke, Growcott, Jim, Lahan, Natalie, Mouchet, Elizabeth, O'Neill, Daniel, Robson, Craig, Shaheen, Fadhel, Thomason, Andrew, Trueman, Dawn, Walker, Graeme, Brooks, Nigel

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Abstract C130: Plucked human scalp hairs: Potential utility as a surrogate tissue for the assessment of therapies targeting the androgen receptor by Growcott, Jim, Brady, Ged, Pickering, Karen, Walker, Jill, Lovick, Susan, Chetty, Raj, Kevill, Helen, Prahladan, Manoj, Grimes, Emma, Harrison, Elliott, Mefo, Timothy, Hodgson, Darren

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The Specific Endothelin A Receptor Antagonist ZD4054: Preclinical and Clinical Results by James, Nicholas D, Growcott, Jim W

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A first-in-man phase I tolerability and pharmacokinetic study of the cyclin-dependent kinase-inhibitor AZD5438 in healthy male volunteers by CAMIDGE, D. Ross, SMETHURST, Dominic, GROWCOTT, Jim, BARRASS, Nigel C, FOSTER, John R, FEBBRARO, Salvatore, SWAISLAND, Helen, HUGHES, Andrew

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