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Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of nov...
by
Hopkins, Brian T.
,
Bame, Eris
,
Bell, Noah
,
Bohnert, Tonika
,
Bowden-Verhoek, Jon K.
,
Bui, Minna
,
Cancilla, Mark T.
,
Conlon, Patrick
,
Cullen, Patrick
,
Erlanson, Daniel A.
,
Fan, Junfa
,
Fuchs-Knotts, Tarra
,
Hansen, Stig
,
Heumann, Stacey
,
Jenkins, Tracy J.
,
Gua, Chuck
,
Liu, Ying
,
Liu, YuTing
,
Lulla, Mukush
,
Marcotte, Douglas
,
Marx, Isaac
,
McDowell, Bob
,
Mertsching, Elisabeth
,
Negrou, Ella
,
Romanowski, Michael J.
,
Scott, Daniel
,
Silvian, Laura
,
Yang, Wenjin
,
Zhong, Min
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Bioorganic & medicinal chemistry
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Bioorganic & Medicinal Chemistry
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Agammaglobulinaemia Tyrosine Kinase - Antagonists & Inhibitors
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Agammaglobulinaemia Tyrosine Kinase - Metabolism
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Biochemistry & Molecular Biology
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Bruton's Tyrosine Kinase
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Bruton’s Tyrosine Kinase
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Chemistry
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Chemistry, Medicinal
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Chemistry, Organic
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Computer Aid Drug Design
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Dose-Response Relationship, Drug
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Drug Discovery
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Fragment Based Screen
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Humans
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Life Sciences & Biomedicine
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Met Id
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Metabolic Soft Spot Switching
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Molecular Structure
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Pharmacology & Pharmacy
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Physical Sciences
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Protein Kinase Inhibitors - Chemistry
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Sciencedirect Journals
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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