Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb by Khan, Mona, Yoo, Seung-Jun, Clijsters, Marnick, Backaert, Wout, Vanstapel, Arno, Speleman, Kato, Lietaer, Charlotte, Choi, Sumin, Hether, Tyler D., Marcelis, Lukas, Nam, Andrew, Pan, Liuliu, Reeves, Jason W., Van Bulck, Pauline, Zhou, Hai, Bourgeois, Marc, Debaveye, Yves, De Munter, Paul, Gunst, Jan, Jorissen, Mark, Lagrou, Katrien, Lorent, Natalie, Neyrinck, Arne, Peetermans, Marijke, Thal, Dietmar Rudolf, Vandenbriele, Christophe, Wauters, Joost, Mombaerts, Peter, Van Gerven, Laura

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer by Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Garcia, Ana P., Lin, Lin, Rideout, William M., Hwang, William L., Schenkel, Jason M., Jaeger, Alex M., Bronson, Roderick T., Westcott, Peter M.K., Hether, Tyler D., Divakar, Prajan, Reeves, Jason W., Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yilmaz, Omer H., Regev, Aviv, Jacks, Tyler

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The spatial landscape of lung pathology during COVID-19 progression by Rendeiro, André F., Ravichandran, Hiranmayi, Bram, Yaron, Chandar, Vasuretha, Kim, Junbum, Meydan, Cem, Park, Jiwoon, Foox, Jonathan, Hether, Tyler, Warren, Sarah, Kim, Youngmi, Reeves, Jason, Salvatore, Steven, Mason, Christopher E., Swanson, Eric C., Borczuk, Alain C., Elemento, Olivier, Schwartz, Robert E.

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Cryptic chytridiomycosis linked to climate and genetic variation in amphibian populations of the southeastern United States by Horner, Ariel A, Hoffman, Eric A, Tye, Matthew R, Hether, Tyler D, Savage, Anna E

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The tumor immune microenvironment of primary and metastatic HER2- positive breast cancers utilizing gene expression and spatial proteomic profiling by Schlam, Ilana, Church, Sarah E, Hether, Tyler D, Chaldekas, Krysta, Hudson, Briana M, White, Andrew M, Maisonet, Emily, Harris, Brent T, Swain, Sandra M

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Minimal residual disease undetectable by next-generation sequencing predicts improved outcome in CLL after chemoimmunotherapy by Thompson, Philip A., Srivastava, Jaya, Peterson, Christine, Strati, Paolo, Jorgensen, Jeffrey L., Hether, Tyler, Keating, Michael J., O'Brien, Susan M., Ferrajoli, Alessandra, Burger, Jan A., Estrov, Zeev, Jain, Nitin, Wierda, William G.

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Correction: Cryptic chytridiomycosis linked to climate and genetic variation in amphibian populations of the southeastern United States by Horner, Ariel A, Hoffman, Eric A, Tye, Matthew R, Hether, Tyler D, Savage, Anna E

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Goldilocks Meets Santa Rosalia: An Ephemeral Speciation Model Explains Patterns of Diversification Across Time Scales by Rosenblum, Erica Bree, Sarver, Brice A. J., Brown, Joseph W., Des Roches, Simone, Hardwick, Kayla M., Hether, Tyler D., Eastman, Jonathan M., Pennell, Matthew W., Harmon, Luke J.

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Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions by Butler, Daniel, Mozsary, Christopher, Meydan, Cem, Foox, Jonathan, Rosiene, Joel, Shaiber, Alon, Danko, David, Afshinnekoo, Ebrahim, MacKay, Matthew, Sedlazeck, Fritz J., Ivanov, Nikolay A., Sierra, Maria, Pohle, Diana, Zietz, Michael, Gisladottir, Undina, Ramlall, Vijendra, Sholle, Evan T., Schenck, Edward J., Westover, Craig D., Hassan, Ciaran, Ryon, Krista, Young, Benjamin, Bhattacharya, Chandrima, Ng, Dianna L., Granados, Andrea C., Santos, Yale A., Servellita, Venice, Federman, Scot, Ruggiero, Phyllis, Fungtammasan, Arkarachai, Chin, Chen-Shan, Pearson, Nathaniel M., Langhorst, Bradley W., Tanner, Nathan A., Kim, Youngmi, Reeves, Jason W., Hether, Tyler D., Warren, Sarah E., Bailey, Michael, Gawrys, Justyna, Meleshko, Dmitry, Xu, Dong, Couto-Rodriguez, Mara, Nagy-Szakal, Dorottya, Barrows, Joseph, Wells, Heather, O’Hara, Niamh B., Rosenfeld, Jeffrey A., Chen, Ying, Steel, Peter A. D., Shemesh, Amos J., Xiang, Jenny, Thierry-Mieg, Jean, Thierry-Mieg, Danielle, Iftner, Angelika, Bezdan, Daniela, Sanchez, Elizabeth, Campion, Thomas R., Sipley, John, Cong, Lin, Craney, Arryn, Velu, Priya, Melnick, Ari M., Shapira, Sagi, Hajirasouliha, Iman, Borczuk, Alain, Iftner, Thomas, Salvatore, Mirella, Loda, Massimo, Westblade, Lars F., Cushing, Melissa, Wu, Shixiu, Levy, Shawn, Chiu, Charles, Schwartz, Robert E., Tatonetti, Nicholas, Rennert, Hanna, Imielinski, Marcin, Mason, Christopher E.

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GENETIC REGULATORY NETWORK MOTIFS CONSTRAIN ADAPTATION THROUGH CURVATURE IN THE LANDSCAPE OF MUTATIONAL (CO)VARIANCE by Hether, Tyler D., Hohenlohe, Paul A.

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816 Evaluating the potential of harnessing anti-leukemia T cells for the treatment of T cell acute lymphoblastic leukemias (T-ALL) by Triplett, Todd, Church, Sarah, Hether, Tyler, Rios, Joshua, Kottapalli, Srividya, Holay, Nisha

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455 Impact of EphB4 and PD-1 treatment on immune infiltrate in advanced bladder cancer by Sadeghi, Sarmad, Hether, Tyler, Yeon, Jason, Mangio, Richard, Reeves, Jason, Liang, Yan, Warren, Sarah, McEachron, Troy, Gill, Parkash

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305 Technical considerations for normalizing digital spatial profiling data with multiple within-patient samples by Hether, Tyler, Howes, Tim, Spencer, Christine, Hollman, Travis, Reeves, Jason, Wells, Danny, Friedman, Claire, LaVallee, Theresa, Wolchok, Jedd, Warren, Sarah

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Fat frogs, mobile genes: unexpected phylogeographic patterns for the ornate chorus frog (Pseudacris ornata) by DEGNER, JACOB F., SILVA, DIANA M., HETHER, TYLER D., DAZA, JUAN M., HOFFMAN, ERIC A.

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COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets by Ziegler, Carly G. K., Heimberg, Graham, Normand, Rachelly, Yang, Yiming, Segerstolpe, Åsa, Abbondanza, Domenic, Fleming, Stephen J., Montoro, Daniel T., Jagadeesh, Karthik A., Dey, Kushal K., Sen, Pritha, Slyper, Michal, Pita-Juárez, Yered H., Phillips, Devan, Biermann, Jana, Bloom-Ackermann, Zohar, Barkas, Nikolaos, Ganna, Andrea, Gomez, James, Melms, Johannes C., Katsyv, Igor, Normandin, Erica, Naderi, Pourya, Popov, Yury V., Raju, Siddharth S., Niezen, Sebastian, Tsai, Linus T.-Y., Siddle, Katherine J., Sud, Malika, Tran, Victoria M., Vellarikkal, Shamsudheen K., Wang, Yiping, Amir-Zilberstein, Liat, Atri, Deepak S., Beechem, Joseph, Brook, Olga R., Chen, Jonathan, Divakar, Prajan, Engreitz, Jesse M., Essene, Adam, Fitzgerald, Donna M., Fropf, Robin, Gazal, Steven, Gould, Joshua, Grzyb, John, Harvey, Tyler, Hether, Tyler, Jané-Valbuena, Judit, Leney-Greene, Michael, Ma, Hui, McCabe, Cristin, McLoughlin, Daniel E., Miller, Eric M., Muus, Christoph, Niemi, Mari, Padera, Robert, Pan, Liuliu, Pant, Deepti, Pe’er, Carmel, Pfiffner-Borges, Jenna, Pinto, Christopher J., Plaisted, Jacob, Reeves, Jason, Ross, Marty, Rudy, Melissa, Rueckert, Erroll H., Siciliano, Michelle, Sturm, Alexander, Waghray, Avinash, Warren, Sarah, Zhang, Shuting, Zollinger, Daniel R., Cosimi, Lisa, Gupta, Rajat M., Hacohen, Nir, Hibshoosh, Hanina, Hide, Winston, Price, Alkes L., Rajagopal, Jayaraj, Tata, Purushothama Rao, Riedel, Stefan, Szabo, Gyongyi, Tickle, Timothy L., Hung, Deborah, Sabeti, Pardis C., Novak, Richard, Rogers, Robert, Ingber, Donald E., Jiang, Z. Gordon, Juric, Dejan, Izar, Benjamin, Stone, James R., Vlachos, Ioannis S., Solomon, Isaac H., Ashenberg, Orr, Porter, Caroline B. M., Li, Bo, Shalek, Alex K., Villani, Alexandra-Chloé, Regev, Aviv

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Genomics and introgression： Discovery and mapping of thousands of species-diagnostic SNPs using RAD sequencing by Hand, Brian K., Hether, Tyler D., Kovach, Ryan P., Muhlfeld, Clint C., Amish, Stephen J., Boyer, Matthew C., O’rourke, Sean M., Miller, Michael R., Lowe, Winsor H., Hohenlohe, Paul A., Luikart, Gordon

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Eight novel tetranucleotide and five cross-species dinucleotide microsatellite loci for the ornate chorus frog (Pseudacris ornata) by DEGNER, JACOB F, HETHER, TYLER D, HOFFMAN, ERIC A

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SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice by Dinnon, 3rd, Kenneth H, Leist, Sarah R, Okuda, Kenichi, Dang, Hong, Fritch, Ethan J, Gully, Kendra L, De la Cruz, Gabriela, Evangelista, Mia D, Asakura, Takanori, Gilmore, Rodney C, Hawkins, Padraig, Nakano, Satoko, West, Ande, Schäfer, Alexandra, Gralinski, Lisa E, Everman, Jamie L, Sajuthi, Satria P, Zweigart, Mark R, Dong, Stephanie, McBride, Jennifer, Cooley, Michelle R, Hines, Jesse B, Love, Miriya K, Groshong, Steve D, VanSchoiack, Alison, Phelan, Stefan J, Liang, Yan, Hether, Tyler, Leon, Michael, Zumwalt, Ross E, Barton, Lisa M, Duval, Eric J, Mukhopadhyay, Sanjay, Stroberg, Edana, Borczuk, Alain, Thorne, Leigh B, Sakthivel, Muthu K, Lee, Yueh Z, Hagood, James S, Mock, Jason R, Seibold, Max A, O'Neal, Wanda K, Montgomery, Stephanie A, Boucher, Richard C, Baric, Ralph S

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Abstract P2-07-03: Correlation of immune-related protein expression with hormone receptor (HR) status and pathologic response to neoadjuvant paclitaxel/trastuzumab/pertuzumab (THP)... by Waks, Adrienne G., Huang, Ying, Hether, Tyler, Ogayo, Esther R, Kadel, Sapana, Alberti, Jillian, Tolaney, Sara M, Krop, Ian E, Divakar, Prajan, Metzger, Otto, O'Donnell, Madison L, Church, Sarah, Winer, Eric P, Guerriero, Jennifer L., Mittendorf, Elizabeth A

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The spatio-temporal landscape of lung pathology in SARS-CoV-2 infection by Rendeiro, André F., Ravichandran, Hiranmayi, Bram, Yaron, Kim, Junbum, Meydan, Cem, Park, Jiwoon, Foox, Jonathan, Hether, Tyler, Warren, Sarah, Kim, Youngmi, Reeves, Jason, Salvatore, Steven, Mason, Christopher E., Swanson, Eric C., Borczuk, Alain C., Elemento, Olivier, Schwartz, Robert E.

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