Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays by MANFREDI, Mark G, ECSEDY, Jeffrey A, WYSONG, Deborah R, JANOWICK, David A, HYER, Marc L, LEROY, Patrick J, GERSHMAN, Rachel E, SILVA, Matthew D, GERMANOS, Melissa S, BOLEN, Joseph B, CLAIBORNE, Christopher F, SELLS, Todd B, CHAKRAVARTY, Arijit, SILVERMAN, Lee, MENGKUN ZHANG, HOAR, Kara M, STROUD, Stephen G, WEI CHEN, SHINDE, Vaishali, HUCK, Jessica J

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Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase by Manfredi, Mark G, Ecsedy, Jeffrey A, Meetze, Kristan A, Balani, Suresh K, Burenkova, Olga, Chen, Wei, Galvin, Katherine M, Hoar, Kara M, Huck, Jessica J, LeRoy, Patrick J, Ray, Emily T, Sells, Todd B, Stringer, Bradley, Stroud, Stephen G, Vos, Tricia J, Weatherhead, Gabriel S, Wysong, Deborah R, Zhang, Mengkun, Bolen, Joseph B, Claiborne, Christopher F

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Vaccination of Cancer Patients Against Telomerase Induces Functional Antitumor CD8+ T Lymphocytes by VONDERHEIDE, Robert H, DOMCHEK, Susan M, ANDERSON, Karen S, HAHN, William C, NADLER, Lee M, SCHULTZE, Joachim L, GEORGE, Daniel J, HOAR, Kara M, CHEN, Dih-Yih, STEPHANS, Katherine F, MASUTOMI, Kenkichi, LODA, Massimo, ZHINAN XIA

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Melanoma Inhibitor of Apoptosis Protein (ML-IAP) Is a Target for Immune-Mediated Tumor Destruction by Schmollinger, Jan C., Vonderheide, Robert H., Hoar, Kara M., Maecker, Britta, Schultze, Joachim L., Hodi, F. Stephen, Soiffer, Robert J., Jung, Ken, Kuroda, Marcelo J., Letvin, Norman L., Greenfield, Edward A., Mihm, Martin, Kutok, Jeffery L., Dranoff, Glenn

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MLN8054, an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo by Huck, Jessica J, Zhang, Mengkun, McDonald, Alice, Bowman, Doug, Hoar, Kara M, Stringer, Bradley, Ecsedy, Jeffery, Manfredi, Mark G, Hyer, Marc L

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Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by aurora A : A novel pharmacodynamic method for measuring aurora a activity by LEROY, Patrick J, HUNTER, John J, HOAR, Kara M, BURKE, Krissy E, SHINDE, Vaishali, RUAN, Jason, BOWMAN, Douglas, GALVIN, Katherine, ECSEDY, Jeffrey A

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Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals by VONDERHEIDE, Robert H, SCHULTZE, Joachim L, SCHNIPPER, Deborah R, BROOKS, Mary W, LETVIN, Norman L, STEPHANS, Katherine F, WUCHERPFENNIG, Kai W, HAHN, William C, NADLER, Lee M, ANDERSON, Karen S, MAECKER, Britta, BUTLER, Marcus O, ZHINAN XIA, KURODA, Marcelo J, VON BERGWELT-BAILDON, Michael S, BEDOR, Michelle M, HOAR, Kara M

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Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia by Jiang, Lei, Park, Ji-Sun, Yin, Ling, Laureano, Rodrigo, Jacquinet, Eric, Yang, Jinsong, Liang, Shi, Frassetto, Andrea, Zhuo, Jenny, Yan, Xinhua, Zhu, Xuling, Fortucci, Steven, Hoar, Kara, Mihai, Cosmin, Tunkey, Christopher, Presnyak, Vlad, Benenato, Kerry E., Lukacs, Christine M., Martini, Paolo G. V., Guey, Lin T.

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Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer by Langston, Steven P, Grossman, Stephen, England, Dylan, Afroze, Roushan, Bence, Neil, Bowman, Douglas, Bump, Nancy, Chau, Ryan, Chuang, Bei-Ching, Claiborne, Christopher, Cohen, Larry, Connolly, Kelly, Duffey, Matthew, Durvasula, Nitya, Freeze, Scott, Gallery, Melissa, Galvin, Katherine, Gaulin, Jeffrey, Gershman, Rachel, Greenspan, Paul, Grieves, Jessica, Guo, Jianping, Gulavita, Nanda, Hailu, Shumet, He, Xingyue, Hoar, Kara, Hu, Yongbo, Hu, Zhigen, Ito, Mitsuhiro, Kim, Mi-Sook, Lane, Scott Weston, Lok, David, Lublinsky, Anya, Mallender, William, McIntyre, Charles, Minissale, James, Mizutani, Hirotake, Mizutani, Miho, Molchinova, Nina, Ono, Koji, Patil, Ashok, Qian, Mark, Riceberg, Jessica, Shindi, Vaishali, Sintchak, Michael D, Song, Keli, Soucy, Teresa, Wang, Yana, Xu, He, Yang, Xiaofeng, Zawadzka, Agatha, Zhang, Ji, Pulukuri, Sai M

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Mechanistic Study of Uba5 Enzyme and the Ufm1 Conjugation Pathway by Gavin, James M., Hoar, Kara, Xu, Qing, Ma, Jingya, Lin, Yafang, Chen, Jiejin, Chen, Wei, Bruzzese, Frank J., Harrison, Sean, Mallender, William D., Bump, Nancy J., Sintchak, Michael D., Bence, Neil F., Li, Ping, Dick, Lawrence R., Gould, Alexandra E., Chen, Jesse J.

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Engineered Stem Cell Antibody Paired Evasion 1 (ESCAPE-1): Paired HSC Epitope Engineering and Upregulation of Fetal Hemoglobin for Antibody-Mediated Autologous Hematopoietic Stem C... by Mondal, Nandini, Harmon, Alexander, Budak, Elizabeth, Zhang, Kathy, Wong, Jeffrey, Rinaldi, Conrad, Olins, Jenny, Hoar, Kara, Menon, Archita Venugopal, White, Moriah, Musenge, Faith, Camblin, Adam, Wolin, Adam, Coisman, Brent, Bai, Tao, Qiao, Kangjian, Patel, Mudra, Decker, Jeremy, Gantzer, Bob, Leete, Thomas, Yu, Yi, Bohnuud, Tanggis, Lee, Seung-Joo, Smith, Sarah, McDonagh, Charlotte F, Gaudelli, Nicole M., Chu, S. Haihua, Hartigan, Adam J., Ciaramella, Giuseppe

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