Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation by Nagase, Reina, Inoue, Daichi, Pastore, Alessandro, Fujino, Takeshi, Hou, Hsin-An, Yamasaki, Norimasa, Goyama, Susumu, Saika, Makoto, Kanai, Akinori, Sera, Yasuyuki, Horikawa, Sayuri, Ota, Yasunori, Asada, Shuhei, Hayashi, Yasutaka, Kawabata, Kimihito Cojin, Takeda, Reina, Tien, Hwei-Fang, Honda, Hiroaki, Abdel-Wahab, Omar, Kitamura, Toshio

Get full text

Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD) by Kitamura, Toshio, Watanabe-Okochi, Naoko, Enomoto, Yutaka, Nakahara, Fumio, Oki, Toshihiko, Komeno, Yukiko, Kato, Naoko, Doki, Noriko, Uchida, Tomoyuki, Kagiyama, Yuki, Togami, Katsuhiro, Kawabata, Kimihito C, Nishimura, Koutarou, Hayashi, Yasutaka, Nagase, Reina, Saika, Makoto, Fukushima, Tsuyoshi, Asada, Shuhei, Fujino, Takeshi, Izawa, Yuto, Horikawa, Sayuri, Fukuyama, Tomofusa, Tanaka, Yosuke, Ono, Ryoichi, Goyama, Susumu, Nosaka, Tetsuya, Kitaura, Jiro, Inoue, Daichi

Get full text

The molecular basis of myeloid malignancies by KITAMURA, Toshio, INOUE, Daichi, OKOCHI-WATANABE, Naoko, KATO, Naoko, KOMENO, Yukiko, LU, Yang, ENOMOTO, Yutaka, DOKI, Noriko, UCHIDA, Tomoyuki, KAGIYAMA, Yuki, TOGAMI, Katsuhiro, KAWABATA, Kimihito C., NAGASE, Reina, HORIKAWA, Sayuri, HAYASHI, Yasutaka, SAIKA, Makoto, FUKUYAMA, Tomofusa, IZAWA, Kumi, OKI, Toshihiko, NAKAHARA, Fumio, KITAURA, Jiro

Get full text

A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies by Inoue, Daichi, Fujino, Takeshi, Sheridan, Paul, Zhang, Yao-zhong, Nagase, Reina, Horikawa, Sayuri, Li, Zaomin, Matsui, Hirotaka, Kanai, Akinori, Saika, Makoto, Yamaguchi, Rui, Kozuka-Hata, Hiroko, Kawabata, Kimihito Cojin, Yokoyama, Akihiko, Goyama, Susumu, Inaba, Toshiya, Imoto, Seiya, Miyano, Satoru, Xu, Mingjiang, Yang, Feng-Chun, Oyama, Masaaki, Kitamura, Toshio

Get full text

Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation by Kamata-Sakurai, Mika, Narita, Yoshinori, Hori, Yuji, Nemoto, Takayuki, Uchikawa, Ryo, Honda, Masaki, Hironiwa, Naoka, Taniguchi, Kenji, Shida-Kawazoe, Meiri, Metsugi, Shoichi, Miyazaki, Taro, Wada, Naoko A, Ohte, Yuki, Shimizu, Shun, Mikami, Hirofumi, Tachibana, Tatsuhiko, Ono, Natsuki, Adachi, Kenji, Sakiyama, Tetsushi, Matsushita, Tomochika, Kadono, Shojiro, Komatsu, Shun-Ichiro, Sakamoto, Akihisa, Horikawa, Sayuri, Hirako, Ayano, Hamada, Koki, Naoi, Sotaro, Savory, Nasa, Satoh, Yasuko, Sato, Motohiko, Noguchi, Yuki, Shinozuka, Junko, Kuroi, Haruka, Ito, Ami, Wakabayashi, Tetsuya, Kamimura, Masaki, Isomura, Fumihisa, Tomii, Yasushi, Sawada, Noriaki, Kato, Atsuhiko, Ueda, Otoya, Nakanishi, Yoshito, Endo, Mika, Jishage, Kou-Ichi, Kawabe, Yoshiki, Kitazawa, Takehisa, Igawa, Tomoyuki

Get full text

Abstract 1851: Responses of a novel tumor selective anti-CD137 agonist antibody activated by elevated extracellular ATP in tumor microenvironment by Kamata-Sakurai, Mika, Narita, Yoshinori, Uchikawa, Ryo, Taniguchi, Kenji, Horikawa, Sayuri, Hamada, Koki, Hori, Yuji, Nemoto, Takayuki, Metsugi, Shoichi, Inatani, Michiyasu, Igawa, Tomoyuki

Get full text

SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS by Inoue, D, Kitaura, J, Matsui, H, Hou, H-A, Chou, W-C, Nagamachi, A, Kawabata, K C, Togami, K, Nagase, R, Horikawa, S, Saika, M, Micol, J-B, Hayashi, Y, Harada, Y, Harada, H, Inaba, T, Tien, H-F, Abdel-Wahab, O, Kitamura, T

Get full text

Human NAT10 Is an ATP-dependent RNA Acetyltransferase Responsible for N4-Acetylcytidine Formation in 18 S Ribosomal RNA (rRNA) by Ito, Satoshi, Horikawa, Sayuri, Suzuki, Tateki, Kawauchi, Hiroki, Tanaka, Yoshikazu, Suzuki, Takeo, Suzuki, Tsutomu

Get full text

Novel roles of ASXL1 in epigenetic regulation by Inoue, Daichi, Horikawa, Sayuri, Matsui, Hirotaka, Nagase, Reina, Saika, Makoto, Kawabata, Kimihito C, Goyama, Susumu, Kitamura, Toshio

Get full text

A C-terminal mutant of CCAAT-enhancer-binding protein α (C/EBPα-Cm ) downregulates Csf1r , a potent accelerator in the progression of acute myeloid leukemia with C/EBPα-Cm by Togami, Katsuhiro, Kitaura, Jiro, Uchida, Tomoyuki, Inoue, Daichi, Nishimura, Koutarou, Kawabata, Kimihito C, Nagase, Reina, Horikawa, Sayuri, Izawa, Kumi, Fukuyama, Tomofusa, Nakahara, Fumio, Oki, Toshihiko, Harada, Yuka, Harada, Hironori, Aburatani, Hiroyuki, Kitamura, Toshio

Get full text

SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS by Inoue, Daichi, Matsui, Hirotaka, Hou, Hsin-An, Chou, Wen-Chien, Nagamachi, Akiko, Kitaura, Jiro, Kawabata, Kimihito Cojin, Togami, Katsuhiro, Nagase, Reina, Horikawa, Sayuri, Saika, Makoto, Micol, Jean-Baptiste, Hayashi, Yasutaka, Harada, Yuka, Harada, Hironori, Tien, Hwei-Fang, Abdel-Wahab, Omar, Kitamura, Toshio

Get full text