Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1 by SONGMIN YING, HAMDY, Freddie C, HELLEDAY, Thomas

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Spatially resolved clonal copy number alterations in benign and malignant tissue by Erickson, Andrew, He, Mengxiao, Berglund, Emelie, Marklund, Maja, Mirzazadeh, Reza, Schultz, Niklas, Kvastad, Linda, Andersson, Alma, Bergenstråhle, Ludvig, Bergenstråhle, Joseph, Larsson, Ludvig, Alonso Galicia, Leire, Shamikh, Alia, Basmaci, Elisa, Díaz De Ståhl, Teresita, Rajakumar, Timothy, Doultsinos, Dimitrios, Thrane, Kim, Ji, Andrew L., Khavari, Paul A., Tarish, Firaz, Tanoglidi, Anna, Maaskola, Jonas, Colling, Richard, Mirtti, Tuomas, Hamdy, Freddie C., Woodcock, Dan J., Helleday, Thomas, Mills, Ian G., Lamb, Alastair D., Lundeberg, Joakim

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Prevention and early detection of prostate cancer by Cuzick, Jack, Prof, Thorat, Mangesh A, MBBS, Andriole, Gerald, Prof, Brawley, Otis W, Prof, Brown, Powel H, Prof, Culig, Zoran, MD, Eeles, Rosalind A, Prof, Ford, Leslie G, MD, Hamdy, Freddie C, Prof, Holmberg, Lars, Prof, Ilic, Dragan, PhD, Key, Timothy J, Prof, Vecchia, Carlo La, Prof, Lilja, Hans, Prof, Marberger, Michael, Prof, Meyskens, Frank L, Prof, Minasian, Lori M, MD, Parker, Chris, MD, Parnes, Howard L, MD, Perner, Sven, Prof, Rittenhouse, Harry, PhD, Schalken, Jack, Prof, Schmid, Hans-Peter, Prof, Schmitz-Dräger, Bernd J, Prof, Schröder, Fritz H, Prof, Stenzl, Arnulf, Prof, Tombal, Bertrand, Prof, Wilt, Timothy J, Prof, Wolk, Alicja, Prof

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Active monitoring, radical prostatectomy, or radiotherapy for localised prostate cancer: study design and diagnostic and baseline results of the ProtecT randomised phase 3 trial by Lane, J Athene, PhD, Donovan, Jenny L, Prof, Davis, Michael, MSc, Walsh, Eleanor, MSc, Dedman, Daniel, MSc, Down, Liz, BSc, Turner, Emma L, PhD, Mason, Malcolm D, Prof, Metcalfe, Chris, PhD, Peters, Tim J, Prof, Martin, Richard M, PhD, Neal, David E, Prof, Hamdy, Freddie C, Prof

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Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts by Seibert, Tyler M, Fan, Chun Chieh, Wang, Yunpeng, Zuber, Verena, Karunamuni, Roshan, Parsons, J Kellogg, Eeles, Rosalind A, Easton, Douglas F, Kote-Jarai, ZSofia, Al Olama, Ali Amin, Garcia, Sara Benlloch, Muir, Kenneth, Grönberg, Henrik, Wiklund, Fredrik, Aly, Markus, Schleutker, Johanna, Sipeky, Csilla, Tammela, Teuvo LJ, Nordestgaard, Børge G, Nielsen, Sune F, Weischer, Maren, Bisbjerg, Rasmus, Røder, M Andreas, Iversen, Peter, Key, Tim J, Travis, Ruth C, Neal, David E, Donovan, Jenny L, Hamdy, Freddie C, Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S, Cybulski, Cezary, Wokolorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Cuk, Katarina, Saum, Kai-Uwe, Park, Jong Y, Sellers, Thomas A, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A, Spurdle, Amanda, Teixeira, Manuel R, Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, Karow, David S, Mills, Ian G, Andreassen, Ole A, Dale, Anders M

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Castration radiosensitizes prostate cancer tissue by impairing DNA double-strand break repair by Tarish, Firas L, Schultz, Niklas, Tanoglidi, Anna, Hamberg, Hans, Letocha, Henry, Karaszi, Katalin, Hamdy, Freddie C, Granfors, Torvald, Helleday, Thomas

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Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma by Dhawan, D, Hamdy, FC, Rehman, I, Patterson, J, Cross, SS, Feeley, KM, Stephenson, Y, Meuth, M, Catto, JWF

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Association analyses identify 31 new risk loci for colorectal cancer susceptibility by Law, Philip J., Timofeeva, Maria, Fernandez-Rozadilla, Ceres, Broderick, Peter, Studd, James, Fernandez-Tajes, Juan, Farrington, Susan, Svinti, Victoria, Palles, Claire, Orlando, Giulia, Sud, Amit, Holroyd, Amy, Penegar, Steven, Theodoratou, Evropi, Vaughan-Shaw, Peter, Campbell, Harry, Zgaga, Lina, Hayward, Caroline, Campbell, Archie, Harris, Sarah, Deary, Ian J., Starr, John, Gatcombe, Laura, Pinna, Maria, Briggs, Sarah, Martin, Lynn, Jaeger, Emma, Sharma-Oates, Archana, East, James, Leedham, Simon, Arnold, Roland, Johnstone, Elaine, Wang, Haitao, Kerr, David, Kerr, Rachel, Maughan, Tim, Kaplan, Richard, Al-Tassan, Nada, Palin, Kimmo, Hänninen, Ulrika A., Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Eriksson, Johan G., Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Mecklin, Jukka-Pekka, Buchanan, Daniel D., Win, Aung-Ko, Hopper, John, Jenkins, Mark E., Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steven, Duggan, David, Casey, Graham, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, Easton, Douglas F., Pharoah, Paul D. P., Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A., Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, Harkin, Andrea, Allan, Karen, McQueen, John, Paul, James, Iveson, Timothy, Saunders, Mark, Butterbach, Katja, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Kirac, Iva, Matošević, Petar, Hofer, Philipp, Brezina, Stefanie, Gsur, Andrea, Cheadle, Jeremy P., Aaltonen, Lauri A., Tomlinson, Ian, Houlston, Richard S., Dunlop, Malcolm G.

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Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers by Page, Elizabeth C., Bancroft, Elizabeth K., Brook, Mark N., Assel, Melissa, Hassan Al Battat, Mona, Thomas, Sarah, Taylor, Natalie, Raghallaigh, Holly Ni, Evans, D. Gareth, Maehle, Lovise, Grindedal, Eli Marie, James, Paul, Mascarenhas, Lyon, McKinley, Joanne, Thomas, Tessy, van Asperen, Christi, Vasen, Hans, Kiemeney, Lambertus A., Ringelberg, Janneke, Jensen, Thomas Dyrsø, Osther, Palle J.S., Helfand, Brian T., Genova, Elena, Oldenburg, Rogier A., Cybulski, Cezary, Ong, Kai-Ren, Lam, Jimmy, Taylor, Louise, Feliubadaló, Lidia, van Zelst-Stams, Wendy, Rosario, Derek J., Domchek, Susan, Powers, Jacquelyn, Buys, Saundra, O'Toole, Karen, Ausems, Margreet G.E.M., Schmutzler, Rita K., Rhiem, Kerstin, Izatt, Louise, Cardoso, Marta, Aprikian, Armen, van Randeraad, Heleen, Davidson, Rosemarie, Longmuir, Mark, Helderman van den Enden, Apollonia T.J.M., Adank, Muriel, Williams, Rachel, Andrews, Lesley, Murphy, Declan G., Halliday, Dorothy, Walker, Lisa, Liljegren, Annelie, Carlsson, Stefan, Morton, Catherine, Snape, Katie, Hanson, Helen, Tischkowitz, Marc, Taylor, Amy, Kirk, Judy, Susman, Rachel, Chen-Shtoyerman, Rakefet, Spigelman, Allan, Pachter, Nicholas, Ahmed, Munaza, Ramon y Cajal, Teresa, Brewer, Carole, Gadea, Neus, van Os, Theo, Gallagher, David, Johannsson, Oskar, Barwell, Julian, Nicolai, Nicola, Friedman, Eitan, Greenhalgh, Lynn, Murthy, Vedang, Saya, Sibel, McGrath, John, Rønlund, Karina, Teo, Soo H., Kast, Karin, Aaronson, Neil K., Ardern-Jones, Audrey, Bangma, Chris H., Dearnaley, David, Tricker, Karen, Eyfjord, Jorunn, Falconer, Alison, Foster, Christopher, Gronberg, Henrik, Hamdy, Freddie C., Stefansdottir, Vigdis, Khoo, Vincent, Lindeman, Geoffrey J., Lubinski, Jan, Mikropoulos, Christos, Mitra, Anita, Moynihan, Clare, Wilson, Penny, Dudderidge, Tim, Offman, Judith

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Functional and quality of life outcomes of localised prostate cancer treatments (Prostate Testing for Cancer and Treatment [ProtecT] study) by Donovan, Jenny L., Walsh, Eleanor I., Avery, Kerry N.L., Peters, Tim J., Doherty, Alan, Gnanapragasam, Vincent, Oxley, Jon, Leung, Hing, Schwaibold, Hartwig, Elliott, Emma, Lennon, Teresa, Salter, Elizabeth, Thompson, Pauline, Blaikie, Jan, Adam, Tonia, Askew, Sarah, Brain, Carole, Cloete, Jenny, Dark, Susan, Dewhurst, Elspeth, Emmerson, Ingrid, Geoghegan, Lisa, Grant, Alison, Goodwin, Louise, Hall, Susie, Hoult, Chloe, Holling, Sharon, Kilner, Sue, Napier, Sally, Pisa, Anna, Taylor, Helen, Thomas, Ayesha, Ward, Claire, Walker, Christy, Benson, Richard, Ferguson, Catherine, Loughrey, Carmel, McClaren, Duncan, Patterson, Helen, Roberts, Trevor, Wilson, Paula, Robinson, Mary, Bhattarai, Selina, Dormer, John, Fernando, Malee, Grigor, Ken, Mayer, Nick, Warren, Anne, Appleby, Helen, Aston, Dean, Chalmers, Graham, Early, Nick, Goddall, Lynda, Heymann, Claire, Hicks, Deborah, Jones, Liza, Lawrence, Gill, Lewis, Geraint, McQueen, Alison, Showler, Helen, Swinscoe, James, Townley, John, Wills, Lucy, Down, Elizabeth, Khazragui, Hanan, Taylor, Hilary, Baker, Susan, Bougard, Chantal, Brewer, Catherine, Coull, Susan, Donohue, Rose, Drew, Jane, Farmer, Rebecca, Fry, Susan, Harris, Belle, Hunt, Helen, Jackson, Vicky, Le Butt, Mandy, Leworthy, Jo, Liddiatt, Tanya, Martin, Alex, Mauree, Jainee, Moulam, Gill, Mutch, Jackie, Parker, Kathleen, Smith, Lynne, Steuart‐Feilding, Tom, Sully, Chris, Torrington, Carol, Koupparis, Anthony, Robinson, Mary, Zietman, Anthony, Hill, Elizabeth, Ng, Siaw Yein, Davies, Charlotte, Hughes, Laura, N'Dow, James, Dearnaley, David, Schröder, Fritz, Roberts, Tracy

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Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial by Martin, Richard M, Turner, Emma L, Young, Grace J, Metcalfe, Chris, Walsh, Eleanor I, Lane, J Athene, Sterne, Jonathan A C, Noble, Sian, Holding, Peter, Ben-Shlomo, Yoav, Williams, Naomi J, Pashayan, Nora, Bui, Mai Ngoc, Albertsen, Peter C, Seibert, Tyler M, Zietman, Anthony L, Oxley, Jon, Adolfsson, Jan, Mason, Malcolm D, Davey Smith, George, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L

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DNA-PKcs and PARP1 Bind to Unresected Stalled DNA Replication Forks Where They Recruit XRCC1 to Mediate Repair by Ying, Songmin, Chen, Zhihui, Medhurst, Annette L, Neal, Jessica A, Bao, Zhengqiang, Mortusewicz, Oliver, McGouran, Joanna, Song, Xinming, Shen, Huahao, Hamdy, Freddie C, Kessler, Benedikt M, Meek, Katheryn, Helleday, Thomas

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Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatmen... by Neal, David E., Donovan, Jenny L., Martin, Richard M., Peters, Tim. J., Bollina, Prasad, Doherty, Alan, Gillatt, David, Hughes, Owen, Paez, Edgar, Rosario, Derek J., Rowe, Edward, Staffurth, John, Altman, Doug G., Hamdy, Freddie C., Lane, J. Athene, Hughes, Owen, Prescott, Stephen, Rowe, Edward, Aning, Jonathan, McNeill, Alan, Schwaibold, Hartwig, Herbert, Phillipa, Jones, Amanda, Lennon, Teresa, Lyons, Norma, Thompson, Pauline, Gray, Catherine, Askew, Sarah, Brain, Carole, Dark, Susan, Davis, Gill, Denizot, Jane, Dewhurst, Elspeth, Emmerson, Ingrid, Grant, Alison, Hawkins, Sarah, Kilner, Sue, Marshall, Fiona, Mellen, Louise, Pisa, Anna, Robson, Lindsay, Samuel, Nikki, Sharkey, Irene, Smith, Donna, Taylor, Helen, Trewick, Nicola, Woodhouse, Colin, Ferguson, Catherine, Graham, John, Howard, Grahame, Law, Alastair, Russell, Simon, Thanvi, Narottam, Oxley, Jon, Robinson, Mary, Bhattarai, Selina, Deshmukh, Neeta, Griffiths, David, Grigor, Ken, Ash, Dominic, Bolton, Steven, Conway, John, Lamb, Susan, Lawrence, Gill, Lewis, Geraint, McQueen, Alison, Moore, Rollo, Potterton, Janet, Showler, Helen, Slade, Stephen, Townley, John, Wills, Lucy, Davies, Linda, Khazragui, Hanan, Noble, Sian, Bellis-Sheldon, Elizabeth, Bowtell, Joanne, Clark, Rebecca, Currer, Rosemary, Delaney, Gill, Farmer, Rebecca, Haddow, Jean, Halpin, Susan, Hattrick, Barbara, Liddiatt, Tanya, Moore, Susan, Wilkins, Zoe, Williams, Sharon, Wilson, Andrea, Zietman, Anthony, Williams, Naomi, Toole, Jessica, Bell, Lindsey, Mauree, Jainnee, Ashby, Deborah, Cowan, Richard, Mellon, Killian, N’Dow, James, Schröder, Fritz, Roberts, Tracy

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A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study by Page, Elizabeth C, Brook, Mark N, McHugh, Jana, Jones, Ann-Britt, Merson, Susan, Ong, Kai Ren, Hoffman, Jonathan, Huber, Camilla, Grindedal, Eli Marie, Stormorken, Astrid, Hanson, Helen, James, Paul, Syngal, Sapna, Barwell, Julian, Teixeira, Manuel R, Macrae, Finlay A, Pachter, Nicholas, Buys, Saundra, Cooney, Kathleen A, Taylor, Amy, Hogben, Matthew, Castro, Elena, Dearnaley, David, Dias, Alexander, Dudderidge, Tim, Hamdy, Freddie C, Mikropoulos, Christos, Mitra, Anita V, Moynihan, Clare, Rennert, Gad, Collier, Rebecca, Adlard, Julian, Alfonso, Rosa, Ball, Darran, Benton, Barbara, Biller, Leah, Burgess, Lucy, Callard, Alice, Carter, Vanda, Catanzaro, Mario, Compton, Cecilia, Cornford, Philip, Costello, Philandra, Coulier, Laura, Douglas, Fiona, Douglas, Emma, Ellery, Natalie, Frydenberg, Mark, Fuller, Debbie, Gabriel, Camila, Genova, Elena, George, Angela, Georgiou, Demetra, Goff, Sally, Goldgar, David, Goodman, Selina, Gray, Catherine, Griffiths, Julie, Gupwell, Karin, Hart, Rachel, Hawkes, Lara, Hilario, Kathrine, Hulick, Peter, Jenkins, Sharon, Josefsberg Ben-Yehoshua, Sagi, Kinsella, Netty, Kumar, Pardeep, Leibovici, Dan, Martin, Phoebe, Murphy, Morgan, Mzazi, Shumi, Nadolski, Maria, Park, Linda, Patel, Nafisa, Paulo Souto, João, Peixoto, Ana, Petelin, Lara, Poile, Charlotte, Purnell, Helen, Rankin, Brigette, Renton, Caroline, Sajoo, Anaar, Saunders, Kathryn, Searle, Anne, Sehra, Ravinder, Shackleton, Kylie, Shaw, Adam, Shevrin, Daniel, Siguake, Kas, Snadden, Lesley, Sorrentino, Margherita, Thomas, Maggie, Townshend, Sharron, Tricker, Karen, Tripathi, Vishakha, Valdagni, Riccardo, Verdon, Lizzie, Vogel, Kristen, Watford, Amy, Offman, Judith

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Polygenic hazard score is associated with prostate cancer in multi-ethnic populations by Huynh-Le, Minh-Phuong, Fan, Chun Chieh, Karunamuni, Roshan, Thompson, Wesley K., Martinez, Maria Elena, Eeles, Rosalind A., Kote-Jarai, Zsofia, Muir, Kenneth, Schleutker, Johanna, Pashayan, Nora, Batra, Jyotsna, Grönberg, Henrik, Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Martin, Richard M., Nielsen, Sune F., Nordestgaard, Børge G., Wiklund, Fredrik, Tangen, Catherine M., Giles, Graham G., Wolk, Alicja, Albanes, Demetrius, Travis, Ruth C., Blot, William J., Zheng, Wei, Sanderson, Maureen, Stanford, Janet L., Mucci, Lorelei A., West, Catharine M. L., Kibel, Adam S., Cussenot, Olivier, Berndt, Sonja I., Koutros, Stella, Sørensen, Karina Dalsgaard, Cybulski, Cezary, Grindedal, Eli Marie, Menegaux, Florence, Khaw, Kay-Tee, Park, Jong Y., Ingles, Sue A., Maier, Christiane, Hamilton, Robert J., Thibodeau, Stephen N., Rosenstein, Barry S., Lu, Yong-Jie, Watya, Stephen, Vega, Ana, Kogevinas, Manolis, Penney, Kathryn L., Huff, Chad, Teixeira, Manuel R., Multigner, Luc, Leach, Robin J., Cannon-Albright, Lisa, Brenner, Hermann, John, Esther M., Kaneva, Radka, Logothetis, Christopher J., Neuhausen, Susan L., De Ruyck, Kim, Pandha, Hardev, Razack, Azad, Newcomb, Lisa F., Fowke, Jay H., Gamulin, Marija, Usmani, Nawaid, Claessens, Frank, Gago-Dominguez, Manuela, Townsend, Paul A., Bush, William S., Roobol, Monique J., Parent, Marie-Élise, Hu, Jennifer J., Mills, Ian G., Andreassen, Ole A., Dale, Anders M., Seibert, Tyler M.

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A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data by Huynh-Le, Minh-Phuong, Fan, Chun Chieh, Karunamuni, Roshan, Walsh, Eleanor I, Turner, Emma L, Lane, J Athene, Martin, Richard M, Neal, David E, Donovan, Jenny L, Hamdy, Freddie C, Parsons, J Kellogg, Eeles, Rosalind A, Easton, Douglas F, Kote-Jarai, Zsofia, Amin Al Olama, Ali, Benlloch Garcia, Sara, Muir, Kenneth, Grönberg, Henrik, Wiklund, Fredrik, Aly, Markus, Schleutker, Johanna, Sipeky, Csilla, Tammela, Teuvo Lj, Nordestgaard, Børge Grønne, Key, Timothy J, Travis, Ruth C, Pharoah, Paul D P, Pashayan, Nora, Khaw, Kay-Tee, Thibodeau, Stephen N, McDonnell, Shannon K, Schaid, Daniel J, Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S, Cybulski, Cezary, Wokolorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa A, Brenner, Hermann, Schöttker, Ben, Holleczek, Bernd, Park, Jong Y, Sellers, Thomas A, Lin, Hui-Yi, Slavov, Chavdar Kroumov, Kaneva, Radka P, Mitev, Vanio I, Batra, Jyotsna, Clements, Judith A, Spurdle, Amanda B, Teixeira, Manuel R, Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Mills, Ian G, Andreassen, Ole A, Dale, Anders M, Seibert, Tyler M

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Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11 are all overexpressed in common cancers by Cross, S S, Hamdy, F C, Deloulme, J C, Rehman, I

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Does the introduction of prostate multiparametric magnetic resonance imaging into the active surveillance protocol for localized prostate cancer improve patient re‐classification?... by Bryant, Richard J., Yang, Bob, Philippou, Yiannis, Lam, Karla, Obiakor, Maureen, Ayers, Jennifer, Chiocchia, Virginia, Gleeson, Fergus, MacPherson, Ruth, Verrill, Clare, Sooriakumaran, Prasanna, Hamdy, Freddie C., Brewster, Simon F.

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Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants by Wu, Lang, Wang, Jifeng, Cai, Qiuyin, Cavazos, Taylor B, Emami, Nima C, Long, Jirong, Shu, Xiao-Ou, Lu, Yingchang, Guo, Xingyi, Bauer, Joshua A, Pasaniuc, Bogdan, Penney, Kathryn L, Freedman, Matthew L, Kote-Jarai, Zsofia, Witte, John S, Haiman, Christopher A, Eeles, Rosalind A, Zheng, Wei

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Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden by Cazier, J. -B., Rao, S. R., McLean, C. M., Walker, A. K., Wright, B. J., Jaeger, E. E. M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J. W., Tomlinson, I. P. M., Kiltie, A. E., Hamdy, F. C.

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