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Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)
by
Schiedel, Matthias
,
Herp, Daniel
,
Hammelmann, Sören
,
Swyter, Sören
,
Lehotzky, Attila
,
Robaa, Dina
,
Oláh, Judit
,
Ovádi, Judit
,
Sippl, Wolfgang
,
Jung, Manfred
Published in
Journal of medicinal chemistry
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HaloTag‐Targeted Sirtuin‐Rearranging Ligand (SirReal) for the Development of Proteolysis‐Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2)
by
Schiedel, Matthias
,
Lehotzky, Attila
,
Szunyogh, Sandor
,
Oláh, Judit
,
Hammelmann, Sören
,
Wössner, Nathalie
,
Robaa, Dina
,
Einsle, Oliver
,
Sippl, Wolfgang
,
Ovádi, Judit
,
Jung, Manfred
Published in
Chembiochem : a European journal of chemical biology
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Chembiochem : A European Journal Of Chemical Biology
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Journal Of Medicinal Chemistry
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Subjects
Chemistry, Medicinal
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Hela Cells
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Humans
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Life Sciences & Biomedicine
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Ligands
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Models, Molecular
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Pharmacology & Pharmacy
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Proteolysis - Drug Effects
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Science & Technology
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Sirtuin 2 - Antagonists & Inhibitors
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Sirtuin 2 - Metabolism
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2 [Thio] N [5 [3 [[1 [4 [2 [[2 (2,6
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4 Azidobutan 1 Aminium Chloride
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Acetylation
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Benzyloxycarbonylleucylleucylleucinal
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Biochemistry & Molecular Biology
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Biodegradation
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Chemistry Techniques, Synthetic
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Chimeras
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Chimäre
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Wiley Blackwell Journals
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Wiley Online Library Open Access
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Acs Crkn Legacy Archives
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American Chemical Society:jisc Collections:american Chemical Society Read & Publish Agreement 2022-2024 (Reading List)
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Wiley
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