Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells by Valente, Liz J., Aubrey, Brandon J., Herold, Marco J., Kelly, Gemma L., Happo, Lina, Scott, Clare L., Newbold, Andrea, Johnstone, Ricky W., Huang, David C.S., Vassilev, Lyubomir T., Strasser, Andreas

Get full text

Maximal killing of lymphoma cells by DNA damage–inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim by Happo, Lina, Cragg, Mark S., Phipson, Belinda, Haga, Jon M., Jansen, Elisa S., Herold, Marco J., Dewson, Grant, Michalak, Ewa M., Vandenberg, Cassandra J., Smyth, Gordon K., Strasser, Andreas, Cory, Suzanne, Scott, Clare L.

Get full text

Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals by Koenen, Paul, Heinzel, Susanne, Carrington, Emma M., Happo, Lina, Alexander, Warren S., Zhang, Jian-Guo, Herold, Marco J., Scott, Clare L., Lew, Andrew M., Strasser, Andreas, Hodgkin, Philip D.

Get full text

Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in mice by Meynet, Ophélie, Zunino, Barbara, Happo, Lina, Pradelli, Ludivine A., Chiche, Johanna, Jacquin, Marie A., Mondragón, Laura, Tanti, Jean-François, Taillan, Bruno, Garnier, Georges, Reverso-Meinietti, Julie, Mounier, Nicolas, Michiels, Jean-François, Michalak, Ewa M., Carles, Michel, Scott, Clare L., Ricci, Jean-Ehrland

Get full text

Transforming Growth Factor-β Directly Induces p53-up-regulated Modulator of Apoptosis (PUMA) during the Rapid Induction of Apoptosis in Myc-driven B-cell Lymphomas by Spender, Lindsay C., Carter, Matthew J., O'Brien, Darren I., Clark, Louise J., Yu, Jian, Michalak, Ewa M., Happo, Lina, Cragg, Mark S., Inman, Gareth J.

Get full text