Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs by Bosiljcic, Momir, Cederberg, Rachel A, Hamilton, Melisa J, LePard, Nancy E, Harbourne, Bryant T, Collier, Jenna L, Halvorsen, Elizabeth C, Shi, Rocky, Franks, S Elizabeth, Kim, Ada Y, Banáth, Judit P, Hamer, Mark, Rossi, Fabio M, Bennewith, Kevin L

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CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development by Melese, Etienne S., Franks, Elizabeth, Cederberg, Rachel A., Harbourne, Bryant T., Shi, Rocky, Wadsworth, Brennan J., Collier, Jenna L., Halvorsen, Elizabeth C., Johnson, Fraser, Luu, Jennifer, Oh, Min Hee, Lam, Vivian, Krystal, Gerald, Hoover, Shelley B., Raffeld, Mark, Simpson, R. Mark, Unni, Arun M., Lam, Wan L., Lam, Stephen, Abraham, Ninan, Bennewith, Kevin L., Lockwood, William W.

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Abstract A02: Oncogenic drivers of lung cancer induce production of CCL5 and recruitment of regulatory T-cells by Franks, Elizabeth, Halvorsen, Elizabeth C., Melese, Etienne, Arun, Unni, Collier, Jenna L., Harbourne, Bryant T., Oh, Min Hee, Vivian, Lam, Krystal, Gerry, English, John C., Lam, Wan L., Lam, Stephen, Abraham, Ninan, Bennewith, Kevin L., Lockwood, William W.

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Abstract A50: Interleukin-33 increases ST2+ regulatory T cells and promotes metastatic tumor growth in the lungs in an amphiregulin-dependent manner by Halvorsen, Elizabeth C., Franks, S. Elizabeth, Wadsworth, Brennan J., Harbourne, Bryant T., Cederberg, Rachel A., Steer, Catherine A., Martinez-Gonzalez, Itziar, Calder, Jack, Lockwood, William W., Bennewith, Kevin L.

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Abstract A108: Distinct immune suppressive myeloid cell populations are induced by hypoxic mammary tumors and differentially promote metastatic tumor growth by Hamilton, Melisa J., Bosiljcic, Momir, LePard, Nancy E., Harbourne, Bryant T., Krystal, Gerald, Bennewith, Kevin L.

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Abstract A9: Immune suppressive myeloid cells induced by hypoxic mammary tumor cells persist after primary tumor resection and promote metastatic growth by Hamilton, Melisa J., Bosiljcic, Momir, Harbourne, Bryant T., LePard, Nancy E., Halvorsen, Elizabeth C., Kim, Ada Y., Banath, Judit P., Krystal, Gerald, Bennewith, Kevin L.

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Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells by Unni, Arun M, Harbourne, Bryant, Oh, Min Hee, Wild, Sophia, Ferrarone, John R, Lockwood, William W, Varmus, Harold

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An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity by Weisser, Nina E., Sanches, Mario, Escobar-Cabrera, Eric, O’Toole, Jason, Whalen, Elizabeth, Chan, Peter W. Y., Wickman, Grant, Abraham, Libin, Choi, Kate, Harbourne, Bryant, Samiotakis, Antonios, Rojas, Andrea Hernández, Volkers, Gesa, Wong, Jodi, Atkinson, Claire E., Baardsnes, Jason, Worrall, Liam J., Browman, Duncan, Smith, Emma E., Baichoo, Priya, Cheng, Chi Wing, Guedia, Joy, Kang, Sohyeong, Mukhopadhyay, Abhishek, Newhook, Lisa, Ohrn, Anders, Raghunatha, Prajwal, Zago-Schmitt, Matteo, Schrag, Joseph D., Smith, Joel, Zwierzchowski, Patricia, Scurll, Joshua M., Fung, Vincent, Black, Sonia, Strynadka, Natalie C. J., Gold, Michael R., Presta, Leonard G., Ng, Gordon, Dixit, Surjit

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Abstract 1005: The bispecific antibody zanidatamab's (ZW25's) unique mechanisms of action and durable anti-tumor activity in HER2-expressing cancers by Weisser, Nina E., Wickman, Grant, Abraham, Libin, O'Toole, Jason, Harbourne, Bryant, Guedia, Joy, Cheng, Chi Wing, Chan, Peter, Browman, Duncan, Gold, Michael R., Josephson, Neil, Dixit, Surjit, Rowse, Gerry

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Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis by O’Farrell, Hannah, Harbourne, Bryant, Kurlawala, Zimple, Inoue, Yusuke, Nagelberg, Amy L., Martinez, Victor D., Lu, Daniel, Oh, Min Hee, Coe, Bradley P., Thu, Kelsie L., Somwar, Romel, Lam, Stephen, Lam, Wan L., Unni, Arun M., Beverly, Levi, Lockwood, William W.

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Abstract 2926: PROTECTTM, a novel trispecific antibody masking platform with integrated immune modulation displays unique activity and differentiated modes of action by von Rossum, Anna, Desjardins, Genevieve, Escalante, Nichole, Wong, Wingkie, Harbourne, Bryant, Li, Janessa, Moreno, Begonia Silva, Raghunatha, Prajwal, Kunze, Richard, Fung, Madeline, Heinkel, Florian, Pratap, Harsh, Haworth, Kevin, Escobar-Cabrera, Eric, Clavette, Brandon, Dixit, Surjit, Weisser, Nina, von Kreudenstein, Thomas Spreter

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Abstract A38: Oncogenes drive production of immunosuppressive cytokines to facilitate lung cancer progression by Franks, Elizabeth, Melese, Etienne, Harbourne, Bryant, Halvorsen, Liz, Cederberg, Rachel, Collier, Jenna, Firmino, Natalie, Luu, Jennifer, Unni, Arun, Oh, Min Hee, Lam, Vivian, Krystal, Gerry, Abraham, Ninan, Bennewith, Kevin, Lockwood, William

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