Development of a Novel Cell-Permeable Protein–Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1 by Huggins, David J, Hardwick, Bryn S, Sharma, Pooja, Emery, Amy, Laraia, Luca, Zhang, Fengzhi, Narvaez, Ana J, Roberts-Thomson, Meredith, Crooks, Alex T, Boyle, Robert G, Boyce, Richard, Walker, David W, Mateu, Natalia, McKenzie, Grahame J, Spring, David R, Venkitaraman, Ashok R

Get full text

The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis by Roche-Molina, Marta, Hardwick, Bryn, Sanchez-Ramos, Cristina, Sanz-Rosa, David, Gewert, Dirk, Cruz, Francisco M., Gonzalez-Guerra, Andres, Andres, Vicente, Palma, Joaquin A., Ibanez, Borja, Mckenzie, Grahame, Bernal, Juan A.

Get full text

Implementing a Multicomponent School-Based Obesity Prevention Intervention: A Qualitative Study by Greaney, Mary L., PhD, Hardwick, Cary K., MA, MS, Spadano-Gasbarro, Jennifer L., PhD, Mezgebu, Solomon, MS, Horan, Christine M., MPH, Schlotterbeck, Sara, BA, Austin, S. Bryn, ScD, Peterson, Karen E., ScD

Get full text

Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2 by Janeček, Matej, Rossmann, Maxim, Sharma, Pooja, Emery, Amy, Huggins, David J., Stockwell, Simon R., Stokes, Jamie E., Tan, Yaw S., Almeida, Estrella Guarino, Hardwick, Bryn, Narvaez, Ana J., Hyvönen, Marko, Spring, David R., McKenzie, Grahame J., Venkitaraman, Ashok R.

Get full text

Causes of thrombocytopenia in dogs in the United Kingdom: A retrospective study of 762 cases by Martín-Ambrosio Francés, Marina, Seth, Mayank, Sharman, Mellora, Pollard, Danica, Ortiz, Ana Liza, Miller, Rachel, Natsiopoulos, Thomas, Walker, David, Jones, Bryn, Hardwick, Joshua, Glanemann, Barbara, Garcia, Andrés Salas, Bacon, Jessica, Selgas, Aida Gómez

Get full text

A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation by Sharma, Pooja, Mahen, Robert, Rossmann, Maxim, Stokes, Jamie E., Hardwick, Bryn, Huggins, David J., Emery, Amy, Kunciw, Dominique L., Hyvönen, Marko, Spring, David R., McKenzie, Grahame J., Venkitaraman, Ashok R.

Get full text

Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity by Cole, Daniel J, Rajendra, Eeson, Roberts-Thomson, Meredith, Hardwick, Bryn, McKenzie, Grahame J, Payne, Mike C, Venkitaraman, Ashok R, Skylaris, Chris-Kriton

Get full text

Computational analysis of phosphopeptide binding to the polo-box domain of the mitotic kinase PLK1 using molecular dynamics simulation by Huggins, David J, McKenzie, Grahame J, Robinson, Daniel D, Narváez, Ana J, Hardwick, Bryn, Roberts-Thomson, Meredith, Venkitaraman, Ashok R, Grant, Guy H, Payne, Mike C

Get full text

Interrogation of the Protein-Protein Interactions between Human BRCA2 BRC Repeats and RAD51 Reveals Atomistic Determinants of Affinity: e1002096 by Cole, Daniel J, Rajendra, Eeson, Roberts-Thomson, Meredith, Hardwick, Bryn, McKenzie, Grahame J, Payne, Mike C, Venkitaraman, Ashok R, Skylaris, Chris-Kriton

Get full text

Computational Analysis of Phosphopeptide Binding to the Polo-Box Domain of the Mitotic Kinase PLK1 Using Molecular Dynamics Simulation: e1000880 by Huggins, David J, McKenzie, Grahame J, Robinson, Daniel D, Narváez, Ana J, Hardwick, Bryn, Roberts-Thomson, Meredith, Venkitaraman, Ashok R, Grant, Guy H, Payne, Mike C

Get full text

The small molecule N-Methyl pyrrolidone tunes the natriuretic peptide hormone system into a pro osteogenic state by McKenzie, Grahame, Hardwick, Bryn, SanMiguel, Blanca, Chopra, Bik, Creasey, Giovanna, Gewert, Dirk, Weber, Franz E

Get full text