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Can optical recordings of membrane potential be used to screen for drug-induced action potential prolongation in single cardiac myocytes?
by
Hardy, M.E.L.
,
Lawrence, C.L.
,
Standen, N.B.
,
Rodrigo, G.C.
Published in
Journal of pharmacological and toxicological methods
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Journal Of Pharmacological And Toxicological Methods
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Subjects
Action Potential
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Action Potentials - Drug Effects
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Animals
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Arrhythmia
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Calibration
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Cardiac Muscle
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Coloring Agents
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Drug Evaluation, Preclinical
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Guinea Pigs
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Guinea-Pig Myocyte
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In Vitro Techniques
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Male
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Membrane Potentials - Drug Effects
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Microscopy, Confocal
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Myocytes, Cardiac - Drug Effects
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Potentiometry
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Pyridinium Compounds - Pharmacology
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Radiometry
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Voltage-Sensitive Dyes
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Elsevier Sciencedirect Journals
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Sciencedirect Journals
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