Lysosomal LAMP1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus by Hassiotis, Sofia, Manavis, Jim, Blumbergs, Peter C., Hattersley, Kathryn J., Carosi, Julian M., Kamei, Makoto, Sargeant, Timothy J.

Get full text

Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer’s disease by Whyte, Lauren S., Fourrier, Célia, Hassiotis, Sofia, Lau, Adeline A., Trim, Paul J., Hein, Leanne K., Hattersley, Kathryn J., Bensalem, Julien, Hopwood, John J., Hemsley, Kim M., Sargeant, Timothy J.

Get full text

PICALM regulates cathepsin D processing and lysosomal function by Hattersley, Kathryn J., Carosi, Julian M., Hein, Leanne K., Bensalem, Julien, Sargeant, Timothy J.

Get full text

Measurement of autophagic flux in humans: an optimized method for blood samples by Bensalem, Julien, Hattersley, Kathryn J., Hein, Leanne K., Teong, Xiao Tong, Carosi, Julian M., Hassiotis, Sofia, Grose, Randall H., Fourrier, Célia, Heilbronn, Leonie K., Sargeant, Timothy J.

Get full text

Lysosomal Dysregulation in the Murine AppNL-G-F/NL-G-F Model of Alzheimer’s Disease by Whyte, Lauren S., Hassiotis, Sofia, Hattersley, Kathryn J., Hemsley, Kim M., Hopwood, John J., Lau, Adeline A., Sargeant, Timothy J.

Get full text

Lipid composition of membrane rafts, isolated with and without detergent, from the spleen of a mouse model of Gaucher disease by Hattersley, Kathryn J., Hein, Leanne K., Fuller, Maria

Get full text

Lysosomal Dysregulation in the Murine App Model of Alzheimer’s Disease by Whyte, Lauren S., Hassiotis, Sofia, Hattersley, Kathryn J., Hemsley, Kim M., Hopwood, John J., Lau, Adeline A., Sargeant, Timothy J.

Get full text

Basal autophagic flux measured in blood correlates positively with age in adults at increased risk of type 2 diabetes by Bensalem, Julien, Teong, Xiao Tong, Hattersley, Kathryn J., Hein, Leanne K., Fourrier, Célia, Liu, Kai, Hutchison, Amy T., Heilbronn, Leonie K., Sargeant, Timothy J.

Get full text

Subcellular Fractionation of Hela Cells for Lysosome Enrichment Using a Continuous Percoll-Density Gradient by Carosi, Julian M, Hattersley, Kathryn J, Cui, Yi, Yang, Zhe, Teasdale, Rohan D, Sargeant, Timothy J

Get full text

Lysosomal LAMP 1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus by Hassiotis, Sofia, Manavis, Jim, Blumbergs, Peter C., Hattersley, Kathryn J., Carosi, Julian M., Kamei, Makoto, Sargeant, Timothy J.

Get full text

Lysosomal Dysregulation in the Murine App NL-G-F/NL-G-F Model of Alzheimer's Disease by Whyte, Lauren S, Hassiotis, Sofia, Hattersley, Kathryn J, Hemsley, Kim M, Hopwood, John J, Lau, Adeline A, Sargeant, Timothy J

Get full text

Developmentally dynamic changes in DNA methylation in the human pancreas by MacCalman, Ailsa, De Franco, Elisa, Franklin, Alice, Flaxman, Christine S, Richardson, Sarah J, Murrall, Kathryn, Burrage, Joe, Walker, Emma M, Morgan, Noel G, Hattersley, Andrew T, Dempster, Emma L, Hannon, Eilis, Jeffries, Aaron R, Owens, Nick D L, Mill, Jonathan

Get full text

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics by Beaumont, Robin N, Warrington, Nicole M, Cavadino, Alana, Tyrrell, Jessica, Nodzenski, Michael, Horikoshi, Momoko, Geller, Frank, Myhre, Ronny, Richmond, Rebecca C, Paternoster, Lavinia, Bradfield, Jonathan P, Kreiner-Møller, Eskil, Huikari, Ville, Metrustry, Sarah, Lunetta, Kathryn L, Painter, Jodie N, Hottenga, Jouke-Jan, Allard, Catherine, Barton, Sheila J, Espinosa, Ana, Marsh, Julie A, Potter, Catherine, Zhang, Ge, Ang, Wei, Berry, Diane J, Bouchard, Luigi, Das, Shikta, Hakonarson, Hakon, Heikkinen, Jani, Helgeland, Øyvind, Hocher, Berthold, Hofman, Albert, Inskip, Hazel M, Jones, Samuel E, Kogevinas, Manolis, Lind, Penelope A, Marullo, Letizia, Medland, Sarah E, Murray, Anna, Murray, Jeffrey C, Njølstad, Pål R, Nohr, Ellen A, Reichetzeder, Christoph, Ring, Susan M, Ruth, Katherine S, Santa-Marina, Loreto, Scholtens, Denise M, Sebert, Sylvain, Sengpiel, Verena, Tuke, Marcus A, Vaudel, Marc, Weedon, Michael N, Willemsen, Gonneke, Wood, Andrew R, Yaghootkar, Hanieh, Muglia, Louis J, Bartels, Meike, Relton, Caroline L, Pennell, Craig E, Chatzi, Leda, Estivill, Xavier, Holloway, John W, Boomsma, Dorret I, Montgomery, Grant W, Murabito, Joanne M, Spector, Tim D, Power, Christine, Järvelin, Marjo-Ritta, Bisgaard, Hans, Grant, Struan F A, Sørensen, Thorkild I A, Jaddoe, Vincent W, Jacobsson, Bo, Melbye, Mads, McCarthy, Mark I, Hattersley, Andrew T, Hayes, M Geoffrey, Frayling, Timothy M, Hivert, Marie-France, Felix, Janine F, Hyppönen, Elina, Lowe, William L, Evans, David M, Lawlor, Debbie A, Feenstra, Bjarke, Freathy, Rachel M

Get full text

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors by Day, Felix R, Hao, Ke, Feenstra, Bjarke, Mahajan, Anubha, Tyrrell, Jessica, Robertson, Neil R, Qiao, Zhen, Nodzenski, Michael, Bradfield, Jonathan P, Geller, Frank, Paternoster, Lavinia, Rueedi, Rico, Lyytikäinen, Leo-Pekka, Cavadino, Alana, Have, Christian T, Vilor-Tejedor, Natalia, Joshi, Peter K, Painter, Jodie N, Ntalla, Ioanna, van Leeuwen, Elisabeth M, Joro, Raimo, Lagou, Vasiliki, Richmond, Rebecca C, Barton, Sheila J, Inskip, Hazel M, Santa-Marina, Loreto, Estivill, Xavier, Marsh, Julie A, Marullo, Letizia, Hocher, Berthold, Lunetta, Kathryn L, Murabito, Joanne M, Allard, Catherine, Bouchard, Luigi, Hivert, Marie-France, Heikkinen, Jani, Morgen, Camilla S, Zhao, Jing Hua, Hemani, Gibran, Bennett, Amanda J, Gaulton, Kyle J, Fernandez-Tajes, Juan, Rosendaal, Frits Richard, Das, Shikta, Willemsen, Gonneke, Standl, Marie, van Beijsterveldt, Catharina E.M, Bonas-Guarch, Silvia, Shields, Beverley M, Knight, Bridget A, Chai, Jin-Fang, Bartels, Meike, Sanchez, Friman, Chawes, Bo L, Loh, Po-Ru, Murray, Anna, Weedon, Michael N, Tönjes, Anke, van Duijn, Cornelia M, Kiess, Wieland, Körner, Antje, Niinikoski, Harri, Raitakari, Olli T, Dedoussis, George V, Teo, Yik-Ying, Saw, Seang-Mei, Montgomery, Grant W, Campbell, Harry, Hayes, M. Geoffrey, Kadarmideen, Haja N, Holm, Jens-Christian, Pennell, Craig E, Adair, Linda S, Borja, Judith B, Mohlke, Karen L, Eriksson, Johan G, Spector, Tim D, Boomsma, Dorret I, Bønnelykke, Klaus, Murray, Jeffrey C, Nohr, Ellen A, Mook-Kanamori, Dennis O, Rivadeneira, Fernando, Hofman, Albert, Jaddoe, Vincent W V, Hansen, Torben, Pisinger, Charlotta, Pedersen, Oluf, Uitterlinden, André G, Hyppönen, Elina, Scholtens, Denise M, Lowe, William L, Davey Smith, George, Timpson, Nicholas J, Grant, Struan F.A, Frayling, Timothy M, Lawlor, Debbie A, Johansson, Stefan, McCarthy, Mark I, Evans, David M

Request full text

Autophagy captures the retromer-TBC1D5 complex to inhibit receptor recycling by Carosi, Julian M., Hein, Leanne K., Sandow, Jarrod J., Dang, Linh V. P., Hattersley, Kathryn, Denton, Donna, Kumar, Sharad, Sargeant, Timothy J.

Get full text

Comparison of chloroquine-like molecules for lysosomal inhibition and measurement of autophagic flux in the brain by Fourrier, Célia, Bryksin, Valerie, Hattersley, Kathryn, Hein, Leanne K., Bensalem, Julien, Sargeant, Timothy J.

Get full text

Phenotypic severity of homozygous GCK mutations causing neonatal or childhood-onset diabetes is primarily mediated through effects on protein stability by Raimondo, Anne, Chakera, Ali J, Thomsen, Soren K, Colclough, Kevin, Barrett, Amy, De Franco, Elisa, Chatelas, Alisson, Demirbilek, Huseyin, Akcay, Teoman, Alawneh, Hussein, Flanagan, Sarah E, Van De Bunt, Martijn, Hattersley, Andrew T, Gloyn, Anna L, Ellard, Sian

Get full text

Relapsing diabetes can result from moderately activating mutations in KCNJ11 by Gloyn, Anna L., Reimann, Frank, Girard, Christophe, Edghill, Emma L., Proks, Peter, Pearson, Ewan R., Temple, I. Karen, Mackay, Deborah J.G., Shield, Julian P.H., Freedenberg, Debra, Noyes, Kathryn, Ellard, Sian, Ashcroft, Frances M., Gribble, Fiona M., Hattersley, Andrew T.

Get full text

A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome by Hein, Leanne K., Apaja, Pirjo M., Hattersley, Kathryn, Grose, Randall H., Xie, Jianling, Proud, Christopher G., Sargeant, Timothy J.

Get full text

Slow, continuous enzyme replacement via spinal CSF in dogs with the paediatric-onset neurodegenerative disease, MPS IIIA by King, Barbara, Marshall, Neil R., Hassiotis, Sofia, Trim, Paul J., Tucker, Justin, Hattersley, Kathryn, Snel, Marten F., Jolly, Robert D., Hopwood, John J., Hemsley, Kim M.

Get full text