Development of an Enantioselective Hydrogenation Based Synthesis of a Glucokinase Activator by Magnus, Nicholas A, Braden, Timothy M, Buser, Jonas Y, DeBaillie, Amy C, Heath, Perry C, Ley, Christopher P, Remacle, Jacob R, Varie, David L, Wilson, Thomas M

Get full text

Practical Asymmetric Synthesis of an Edivoxetine·HCl Intermediate via an Efficient Diazotization Process by Kopach, Michael E, Heath, Perry C, Scherer, Roger B, Pietz, Mark A, Astleford, Bret A, McCauley, Mary Kay, Singh, Utpal K, Wong, Sze Wing, Coppert, David M, Kerr, Mark S, Houghton, Peter G, Rhodes, Gary A, Tharp, Gregg A

Get full text

Development of a Practical Synthesis of an Aminoindanol-Derived M1 Agonist by Hansen, Marvin M, Borders, Sandra S. K, Clayton, Marcella T, Heath, Perry C, Kolis, Stanley P, Larsen, Samuel D, Linder, Ryan J, Reutzel-Edens, Susan M, Smith, Justin C, Tameze, Shella L, Ward, Jeffrey A, Weigel, Leland O

Get full text

An efficient acylation/base-catalyzed cyclization of thioureas affords N,N′-disubstituted thiobarbituric acids by Heath, Perry C, Huang, Charles Q, Lowe, Richard F, McCarthy, James R, Weigel, Leland O, Whitten, Jeffery P

Get full text

Resolution of δ-Lactams Provides Access to Nonracemic Benzoquinolinones:  The Synthesis of LY300502 and LY300503 by Astleford, Bret A, Audia, James E, Deeter, Jack, Heath, Perry C, Janisse, Samantha K, Kress, Thomas J, Wepsiec, James P, Weigel, Leland O

Get full text

Separation and purification of azetidinyl methyl sulfinates using preparative high-performance liquid chromatography by Brown, Frank, Heath, Perry C.

Get full text

A diastereoselective tandem metalloenamine alkylation/aza-annulation of β-tetralones expedites the synthesis of benzoquinolinones by Audia, James E., Droste, James J., Dunigan, James M., Bowers, John, Heath, Perry C., Holme, Dale W., Eifert, Jill H., Kay, Harry A., Miller, Richard D., Olivares, Jorge M., Rainey, Thomas F., Weigel, Leland O.

Get full text

Flavored e-cigarette use: Characterizing youth, young adult, and adult users by Harrell, M.B, Weaver, S.R, Loukas, A, Creamer, M, Marti, C.N, Jackson, C.D, Heath, J.W, Nayak, P, Perry, C.L, Pechacek, T.F, Eriksen, M.P

Get full text

The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes by Schield, Drew R, Card, Daren C, Hales, Nicole R, Perry, Blair W, Pasquesi, Giulia M, Blackmon, Heath, Adams, Richard H, Corbin, Andrew B, Smith, Cara F, Ramesh, Balan, Demuth, Jeffery P, Betrán, Esther, Tollis, Marc, Meik, Jesse M, Mackessy, Stephen P, Castoe, Todd A

Get full text

Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA by Ramasamy, Adaikalavan, Kuokkanen, Mikko, Vedantam, Sailaja, Gajdos, Zofia K, Couto Alves, Alexessander, Lyon, Helen N, Ferreira, Manuel A R, Strachan, David P, Zhao, Jing Hua, Abramson, Michael J, Brown, Matthew A, Coin, Lachlan, Dharmage, Shyamali C, Duffy, David L, Haahtela, Tari, Heath, Andrew C, Janson, Christer, Kähönen, Mika, Khaw, Kay-Tee, Laitinen, Jaana, Le Souef, Peter, Lehtimäki, Terho, Madden, Pamela A F, Marks, Guy B, Martin, Nicholas G, Matheson, Melanie C, Palmer, Cameron D, Palotie, Aarno, Pouta, Anneli, Robertson, Colin F, Viikari, Jorma, Widen, Elisabeth, Wjst, Matthias, Jarvis, Deborah L, Montgomery, Grant W, Thompson, Philip J, Wareham, Nick, Eriksson, Johan, Jousilahti, Pekka, Laitinen, Tarja, Pekkanen, Juha, Raitakari, Olli T, O'Connor, George T, Salomaa, Veikko, Jarvelin, Marjo-Riitta, Hirschhorn, Joel N

Get full text

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns by Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Danyi, Alexandra, de Ridder, Jeroen, van Herpen, Carla, Lolkema, Martijn P., Steeghs, Neeltje, Getz, Gad, Morris, Quaid D., Stein, Lincoln D.

Get full text

Sex differences in oncogenic mutational processes by Li, Constance H., Prokopec, Stephenie D., Sun, Ren X., Yousif, Fouad, Schmitz, Nathaniel, Boutros, Paul C.

Get full text

Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson Disease: A Randomized Controlled Trial by Weaver, Frances M, Follett, Kenneth, Stern, Matthew, Hur, Kwan, Harris, Crystal, Marks, William J, Rothlind, Johannes, Sagher, Oren, Reda, Domenic, Moy, Claudia S, Pahwa, Rajesh, Burchiel, Kim, Hogarth, Penelope, Lai, Eugene C, Duda, John E, Holloway, Kathryn, Samii, Ali, Horn, Stacy, Bronstein, Jeff, Stoner, Gatana, Heemskerk, Jill, Huang, Grant D, CSP 468 Study Group, for the

Get full text

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations by Zhang, Yiqun, Chen, Fengju, Fonseca, Nuno A., He, Yao, Fujita, Masashi, Nakagawa, Hidewaki, Zhang, Zemin, Brazma, Alvis, Creighton, Chad J.

Get full text

CaveCrawler: An interactive analysis suite for cavefish bioinformatics by Perry, Annabel, McGaugh, Suzanne E, Keene, Alex C, Blackmon, Heath

Get full text

Ultrasonographic measures of synovitis in an early phase clinical trial: a double-blind, randomised, placebo and comparator controlled phase IIa clinical trial of GW274150 (a selec... by SEYMOUR, M, PETAVY, F, HEATH, K, PRODANOVIC, S, RADUNOVIC, G, PILIPOVIC, N, DAMJANOV, N, TAYLOR, P. C, CHIESA, F, PERRY, H, LUKEY, P. T, BINKS, M, DONATIEN, P. D, FREIDIN, A. J, ECKERSLEY, R. J, MCCLINTON, C

Get full text

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples by Bailey, Matthew H., Meyerson, William U., Dursi, Lewis Jonathan, Wang, Liang-Bo, Dong, Guanlan, Liang, Wen-Wei, Weerasinghe, Amila, Li, Shantao, Li, Yize, Kelso, Sean, Saksena, Gordon, Ellrott, Kyle, Wendl, Michael C., Wheeler, David A., Getz, Gad, Simpson, Jared T., Gerstein, Mark B., Ding, Li

Get full text

Correlates of opioid and benzodiazepine co-prescription among people living with HIV in British Columbia, Canada: A population-level cohort study by Parent, Stephanie, Nolan, Seonaid, Fairbairn, Nadia, Ye, Monica, Wu, Anthony, Montaner, Julio, Barrios, Rolando, Ti, Lianping, Barrios, Rolando, Daly, Patty, Gilbert, Mark, Gustafson, Reka, Kendall, Perry R.W., Panessa, Ciro, McGowan, Gina, South, Nancy, Heath, Kate, Hogg, Robert S., Montaner, Julio S.G.

Get full text

Genetic association study of childhood aggression across raters, instruments, and age by Ip, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, St Pourcain, Beate, Bolhuis, Koen, Zafarmand, Hadi, Gordon, Scott, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Peterson, Roseann E., Prinz, Joseph A., Seppälä, Ilkka, Ahluwalia, Tarunveer S., Day, Felix R., Allegrini, Andrea G., Lu, Yi, Martin, Joanna, Bosch, Rosa, Español, Gemma, Morosoli, José J., Scott, James G., Evans, Luke M., Sugden, Karen, Alemany, Silvia, Sass, Lærke, Ruth, Kate, Tyrrell, Jess, Davies, Gareth E., Ehli, Erik A., De Zeeuw, Eveline, Van Beijsterveldt, Toos C.E.M., Larsson, Henrik, Verhulst, Frank C., Amin, Najaf, Korhonen, Tellervo, Rose, Richard J., Uitterlinden, André G., Heath, Andrew C., Madden, Pamela, Haavik, Jan, Harris, Jennifer R., Njolstad, Pal Rasmus, Lu, Qing, Henders, Anjali K., Mamun, Abdullah, Najman, Jackob M., Brown, Sandy, Krauter, Kenneth, Reynolds, Chandra, Smolen, Andrew, Stallings, Michael, Wadsworth, Sally, Wall, Tamara L., Miller, Allison, Hakulinen, Christian, Pulkki-Råback, Laura, Havdahl, Alexandra, Perry, John R. B., Lopez-Espinosa, Maria-Jose, Bønnelykke, Klaus, Sunyer, Jordi, Arseneault, Louise, Standl, Marie, Heinrich, Joachim, Boden, Joseph, Pearson, John, Kennedy, Martin, Eaves, Lindon J., Maes, Hermine H., Hewitt, John, Costello, Elizabeth J., Williams, Gail M., Wray, Naomi, Järvelin, Marjo-Riitta, McGue, Matt, Iacono, William, Moffitt, Terrie E., Whitehouse, Andrew, Pennell, Craig E., Klump, Kelly L., Dick, Danielle M., Reichborn-Kjennerud, Ted, Martin, Nicholas G., Medland, Sarah E., Vrijkotte, Tanja, Kaprio, Jaakko, Tiemeier, Henning, Hartman, Catharina A., Oldehinkel, Albertine J., Casas, Miquel, Ribasés, Marta, Lichtenstein, Paul, Lundström, Sebastian, Plomin, Robert

Get full text

Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations by Zhang, Yiqun, Chen, Fengju, Fonseca, Nuno A., He, Yao, Fujita, Masashi, Nakagawa, Hidewaki, Zhang, Zemin, Brazma, Alvis, Creighton, Chad J.

Get full text