Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents by Altimari, Jarrad M., Hockey, Samantha C., Boshoff, Helena I., Sajid, Andaleeb, Henderson, Luke C.

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Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones by Basarab, Gregory S, Ghorpade, Sandeep, Gibhard, Liezl, Mueller, Rudolf, Njoroge, Mathew, Peton, Nashied, Govender, Preshendren, Massoudi, Lisa M, Robertson, Gregory Thomas, Lenaerts, Anne J, Boshoff, Helena Ingrid, Joerss, Douglas, Parish, Tanya, Durand-Reville, Thomas F, Perros, Manos, Singh, Vinayak, Chibale, Kelly

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Rationally Designed Nucleoside Antibiotics That Inhibit Siderophore Biosynthesis of Mycobacterium tuberculosis by SOMU, Ravindranadh V., BOSHOFF, Helena, QIAO, Chunhua, BENNETT, Eric M., BARRY, Clifton E., ALDRICH, Courtney C.

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MEPicides: α,β-unsaturated Fosmidomycin N‑Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1‑Deoxy‑d‑xylulose-5-phosphate reductoisomerase by Wang, Xu, Edwards, Rachel L., Ball, Haley S., Heidel, Kenneth M., Brothers, Robert C., Johnson, Claire, Haymond, Amanda, Girma, Misgina, Dailey, Allyson, Roma, Jose Santinni, Boshoff, Helena I., Osbourn, Damon M., Meyers, Marvin J., Couch, Robin D., Odom John, Audrey R., Dowd, Cynthia S.

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Non-Nucleoside Inhibitors of BasE, an Adenylating Enzyme in the Siderophore Biosynthetic Pathway of the Opportunistic Pathogen Acinetobacter baumannii by Neres, João, Engelhart, Curtis A, Drake, Eric J, Wilson, Daniel J, Fu, Peng, Boshoff, Helena I, Barry, Clifton E, Gulick, Andrew M, Aldrich, Courtney C

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Structure−Activity Relationships at the 5-Position of Thiolactomycin:  An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuber... by KIM, Pilho, ZHANG, Yong-Mei, SHENOY, Gautham, NGUYEN, Quynh-Anh, BOSHOFF, Helena I., MANJUNATHA, Ujjini H., GOODWIN, Michael B., LONSDALE, John, PRICE, Allen C., MILLER, Darcie J., DUNCAN, Ken, WHITE, Stephen W., ROCK, Charles O., BARRY, Clifton E., DOWD, Cynthia S.

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Identification of β‑Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions by Gold, Ben, Zhang, Jun, Quezada, Landys Lopez, Roberts, Julia, Ling, Yan, Wood, Madeleine, Shinwari, Wasima, Goullieux, Laurent, Roubert, Christine, Fraisse, Laurent, Bacqué, Eric, Lagrange, Sophie, Filoche-Rommé, Bruno, Vieth, Michal, Hipskind, Philip A, Jungheim, Louis N, Aubé, Jeffrey, Scarry, Sarah M, McDonald, Stacey L, Li, Kelin, Perkowski, Andrew, Nguyen, Quyen, Dartois, Véronique, Zimmerman, Matthew, Olsen, David B, Young, Katherine, Bonnett, Shilah, Joerss, Douglas, Parish, Tanya, Boshoff, Helena I, Arora, Kriti, Barry, Clifton E, Guijarro, Laura, Anca, Sara, Rullas, Joaquín, Rodríguez-Salguero, Beatriz, Martínez-Martínez, Maria S, Porras-De Francisco, Esther, Cacho, Monica, Barros-Aguirre, David, Smith, Paul, Berthel, Steven J, Nathan, Carl, Bates, Robert H

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Some Nigerian anti-tuberculosis ethnomedicines: A preliminary efficacy assessment by Ibekwe, Nneka N., Nvau, John B., Oladosu, Peters O., Usman, Auwal M., Ibrahim, Kolo, Boshoff, Helena I., Dowd, Cynthia S., Orisadipe, Abayomi T., Aiyelaagbe, Olapeju, Adesomoju, Akinbo A., Barry, Clifton E., Okogun, Joseph I.

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5‘-O-[(N-Acyl)sulfamoyl]adenosines as Antitubercular Agents that Inhibit MbtA:  An Adenylation Enzyme Required for Siderophore Biosynthesis of the Mycobactins by Qiao, Chunhua, Gupte, Amol, Boshoff, Helena I, Wilson, Daniel J, Bennett, Eric M, Somu, Ravindranadh V, Barry, Clifton E, Aldrich, Courtney C

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Non-transpeptidase binding arylthioether β-lactams active against Mycobacterium tuberculosis and Moraxella catarrhalis by Beck, Tim N., Lloyd, Dina, Kuskovsky, Rostislav, Minah, Jeanette, Arora, Kriti, Plotkin, Balbina J., Green, Jacalyn M., Boshoff, Helena I., Barry, Clifton, Deschamps, Jeffrey, Konaklieva, Monika I.

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Design, Synthesis, and Biological Evaluation of β-Ketosulfonamide Adenylation Inhibitors as Potential Antitubercular Agents by Vannada, Jagadeshwar, Bennett, Eric M, Wilson, Daniel J, Boshoff, Helena I, Barry, Clifton E, Aldrich, Courtney C

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Inside Cover: Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents (ChemMedChem 5/2015) by Altimari, Jarrad M., Hockey, Samantha C., Boshoff, Helena I., Sajid, Andaleeb, Henderson, Luke C.

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Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis by Gorla, Suresh Kumar, Zhang, Yan, Rabideau, Meaghan M, Qin, Aiping, Chacko, Shibin, House, Amanda L, Johnson, Corey R, Mandapati, Kavitha, Bernstein, Hannah M, McKenney, Elizabeth S, Boshoff, Helena, Zhang, Minjia, Glomski, Ian J, Goldberg, Joanna B, Cuny, Gregory D, Mann, Barbara J, Hedstrom, Lizbeth

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Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis by Park, Yumi, Pacitto, Angela, Bayliss, Tracy, Cleghorn, Laura A. T, Wang, Zhe, Hartman, Travis, Arora, Kriti, Ioerger, Thomas R, Sacchettini, Jim, Rizzi, Menico, Donini, Stefano, Blundell, Tom L, Ascher, David B, Rhee, Kyu, Breda, Ardala, Zhou, Nian, Dartois, Veronique, Jonnala, Surendranadha Reddy, Via, Laura E, Mizrahi, Valerie, Epemolu, Ola, Stojanovski, Laste, Simeons, Fred, Osuna-Cabello, Maria, Ellis, Lucy, MacKenzie, Claire J, Smith, Alasdair R. C, Davis, Susan H, Murugesan, Dinakaran, Buchanan, Kirsteen I, Turner, Penelope A, Huggett, Margaret, Zuccotto, Fabio, Rebollo-Lopez, Maria Jose, Lafuente-Monasterio, Maria Jose, Sanz, Olalla, Diaz, Gracia Santos, Lelièvre, Joël, Ballell, Lluis, Selenski, Carolyn, Axtman, Matthew, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Bösche, Markus, Drewes, Gerard, Freiberg, Gail M, Kurnick, Matthew D, Srikumaran, Myron, Kempf, Dale J, Green, Simon R, Ray, Peter C, Read, Kevin, Wyatt, Paul, Barry, Clifton E, Boshoff, Helena I

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Dual-target inhibitors of mycobacterial aminoacyl-tRNA synthetases among -benzylidene-′-thiazol-2-yl-hydrazines by Kovalenko, Oksana P, Volynets, Galyna P, Rybak, Mariia Yu, Starosyla, Sergiy A, Gudzera, Olga I, Lukashov, Sergiy S, Bdzhola, Volodymyr G, Yarmoluk, Sergiy M, Boshoff, Helena I, Tukalo, Michael A

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Dual-target inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N′-thiazol-2-yl-hydrazines† †Electronic supplementary information (ESI) available. See DOI: 1... by Kovalenko, Oksana P., Volynets, Galyna P., Rybak, Mariia Yu, Starosyla, Sergiy A., Gudzera, Olga I., Lukashov, Sergiy S., Bdzhola, Volodymyr G., Yarmoluk, Sergiy M., Boshoff, Helena I., Tukalo, Michael A.

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Novel 1,4-substituted-1,2,3-triazoles as anti-tubercular agents by Altimari, Jarrad M., Hockey, Samantha C., Boshoff, Helena I., Sajid, Andaleeb, Henderson, Luke C.

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Integrated virus-host methylome analysis in head and neck squamous cell carcinoma by Wilson, Gareth A, Lechner, Matthias, Köferle, Anna, Caren, Helena, Butcher, Lee M, Feber, Andrew, Fenton, Tim, Jay, Amrita, Boshoff, Chris, Beck, Stephan

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Updating and curating metabolic pathways of TB by Slayden, Richard A, Jackson, Mary, Zucker, Jeremy, Ramirez, Melissa V, Dawson, Clinton C, Crew, Rebecca, Sampson, Nicole S, Thomas, Suzanne T, Jamshidi, Neema, Sisk, Peter, Caspi, Ron, Crick, Dean C, McNeil, Michael R, Pavelka, Martin S, Niederweis, Michael, Siroy, Axel, Dona, Valentina, McFadden, Johnjoe, Boshoff, Helena, Lew, Jocelyne M

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Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry by Ge, Ying, ElNaggar, Mariam, Sze, Siu Kwan, Oh, Han Bin, Begley, Tadhg P, McLafferty, Fred W, Boshoff, Helena, Barry, Clifton E

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