Where the “ruber” Meets the Road: Using the Genome of the Red Diamond Rattlesnake to Unravel the Evolutionary Processes Driving Venom Evolution by Hirst, Samuel R, Rautsaw, Rhett M, VanHorn, Cameron M, Beer, Marc A, McDonald, Preston J, Rosales García, Ramsés Alejandro, Rodriguez Lopez, Bruno, Rubio Rincón, Alexandra, Franz Chávez, Hector, Vásquez-Cruz, Víctor, Kelly Hernández, Alfonso, Storfer, Andrew, Borja, Miguel, Castañeda-Gaytán, Gamaliel, Frandsen, Paul B, Parkinson, Christopher L, Strickland, Jason L, Margres, Mark J

Get full text

Global Prevalence of Chronic Kidney Disease - A Systematic Review and Meta-Analysis by Hill, Nathan R, Fatoba, Samuel T, Oke, Jason L, Hirst, Jennifer A, O'Callaghan, Christopher A, Lasserson, Daniel S, Hobbs, F D Richard

Get full text

Epiclomal: Probabilistic clustering of sparse single-cell DNA methylation data by P. E. de Souza, Camila, Andronescu, Mirela, Masud, Tehmina, Kabeer, Farhia, Biele, Justina, Laks, Emma, Lai, Daniel, Ye, Patricia, Brimhall, Jazmine, Wang, Beixi, Su, Edmund, Hui, Tony, Cao, Qi, Wong, Marcus, Moksa, Michelle, Moore, Richard A, Hirst, Martin, Aparicio, Samuel, Shah, Sohrab P

Get full text

A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis by Berg, Tobias, Thoene, Silvia, Yap, Damian, Wee, Tracee, Schoeler, Nathalie, Rosten, Patty, Lim, Emilia, Bilenky, Misha, Mungall, Andrew J., Oellerich, Thomas, Lee, Sherry, Lai, Courteney K., Umlandt, Patricia, Salmi, Anisa, Chang, Harry, Yue, Lisa, Lai, David, Cheng, S.-W. Grace, Morin, Ryan D., Hirst, Martin, Serve, Hubert, Marra, Marco A., Morin, Gregg B., Gascoyne, Randy D., Aparicio, Samuel A., Humphries, R. Keith

Get full text

Comprehensive molecular characterization of urothelial bladder carcinoma by Weinstein, John N, Akbani, Rehan, Broom, Bradley M, Wang, Wenyi, Verhaak, Roeland G. W, McConkey, David

Get full text

The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery by Adams, David, Altucci, Lucia, Amit, Ido, Aparicio, Samuel, Arima, Takahiro, Asnafi, Vahid, Bae, Jae-Bum, Bassler, Kevin, Bilenky, Mikhail, Boehm, Bernhard, Bourque, Guillaume, Brors, Benedikt, Bussemakers, Marion J., Chadwick, Lisa, Chen, Wei, Cheung, Tom H., Choi, Nak Hyen, Chung, Ho-Ryun, Clarke, Laura, Dermitzakis, Manolis, Dylag, Tomasz, Eaves, Connie J., Ebert, Peter, Eils, Jürgen, Enver, Tariq, Ferguson-Smith, Anne, Fitzgibbon, Jude, Flicek, Paul, Fraser, Peter, Gasparoni, Nina, Gasparoni, Gilles, Heath, Simon, Helin, Kristian, Hitz, Benjamin C., Horsthemke, Bernhard, Ip, Nancy Y., Ito, Takashi, Jenuwein, Thomas, Joly, Yann, Kanai, Yae, Kang, Hee Gyung, Kiemer, Alexandra K., Kim, Song Cheol, Kim, Bong-Jo, Lehrach, Hans, Leitão, Elsa, Lengauer, Thomas, Lernmark, Åke, Leung, Gilberto K.K., Leung, Danny, Ma, Yussanne, Martin-Subero, Jose Ignacio, Maschke, Karen, Merten, Christoph, Minucci, Saverio, Mitsuyama, Totai, Moore, Richard A., Nordström, Karl, Norstedt, Irene, Ouellette, Francis, Pap, Thomas, Pelicci, Pier Giuseppe, Phillips, Anthony G., Polansky, Julia, Pospisilik, J. Andrew, Prabhakar, Shyam, Procaccini, Dena C., Radbruch, Andreas, Rajewsky, Nikolaus, Rakyan, Vardham, Richardson, David, Rothstein, Mark, Sasaki, Hiroyuki, Sauer, Sascha, Schmidt, Florian, Schultze, Joachim L., Schulyer, Ronald P., Schulz, Marcel, Siebert, Reiner, Sinha, Anupam, Soranzo, Nicole, Spivakov, Mikhail, Steidl, Christian, Suzuki, Narumi, Torrents, David, Tyson, Frederick L., Ullrich, Sebastian, Ushijima, Toshikazu, Valencia, Alfonso, Wallace, Chris, Weber, Stephanie, Weiler, Nina, Weng, Andrew, Wilder, Steven, Yamashita, Yasuhiro, Yap, Desmond Y., Yip, Kevin Y., Yip, Stephen, Zerbino, Daniel, Zipprich, Gideon

Get full text

Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial by Seymour, Matthew T, Prof, Thompson, Lindsay C, MSc, Wasan, Harpreet S, Prof, Middleton, Gary, MD, Brewster, Alison E, MD, Shepherd, Stephen F, MD, O'Mahony, M Sinead, MBBS, Maughan, Timothy S, Prof, Parmar, Mahesh, Prof, Langley, Ruth E, PhD

Get full text

Clonal Analysis via Barcoding Reveals Diverse Growth and Differentiation of Transplanted Mouse and Human Mammary Stem Cells by Nguyen, Long V., Makarem, Maisam, Carles, Annaick, Moksa, Michelle, Kannan, Nagarajan, Pandoh, Pawan, Eirew, Peter, Osako, Tomo, Kardel, Melanie, Cheung, Alice M.S., Kennedy, William, Tse, Kane, Zeng, Thomas, Zhao, Yongjun, Humphries, R. Keith, Aparicio, Samuel, Eaves, Connie J., Hirst, Martin

Get full text

Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia by Kusakabe, Manabu, Sun, Ann Chong, Tyshchenko, Kateryna, Wong, Rachel, Nanda, Aastha, Shanna, Claire, Gusscott, Samuel, Chavez, Elizabeth A., Lorzadeh, Alireza, Zhu, Alice, Hill, Ainsleigh, Hung, Stacy, Brown, Scott, Babaian, Artem, Wang, Xuehai, Holt, Robert A., Steidl, Christian, Karsan, Aly, Humphries, R. Keith, Eaves, Connie J., Hirst, Martin, Weng, Andrew P.

Get full text

Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases by Kennedy, D., Parappally, C. P., Zafar, S., Samuel, N., Wheatley, K., Nijjar, R. S., Heath, J., Welbourn, H., Blazeby, J. M., Tang, C.‐B., Cowley, J. B., Hodgkins, K. A., Brennan, S., Zhang, C., Jones, M. J., Kimble, A., Jones, E., Gough, M., Downing, J., Chauhan, N., Wild, J. R. L., Rao, S. T V., Siddiqi, N., Sen, G., Old, O. J., Shah, R., Weaver, S., Lammy, S., Mohamed, S., Arhi, C., Giwa Nusrat Iqbal, L., Willson, P. D., Woodman, T., Lloyd, D., Jambulingam, P., Acharya, V., Larkin, D., Law, J., Chang, J., Rate, A. J., Robinson, S., Al‐Muhktar, A., Martin, J., Alagaratnam, S., Hussain, A. A., Kansal, N., Siddiqui, Z., Akhtar, M., Raza, S., Haque, M., Wood, C. P. J., Varghase, J., Bradley, D., Rengifo, C., Finlay, I., Hossack, M. R., Turner, P., Jones, G. H., Carty, N., Panteleimonitis, S., Hargreaves, A., Longbotham, D. A., Khan, M. A., Derbyshire, L., Dickson‐Lowe, R., Mirza, D., Al Amari, K., Kaur, P., Newton, K., Al‐Bahrani, A. Z., Segaran, A., Wadley, M., Hebbar, M., Hossain, T., Pannu, A., Chan, W. M., Connelly, M., Spence, G., Shabo, W., Iskandar, E., McEntee, G. P., Kelly, M. E., McDermott, F., Prince, S., Buchan, J., Grant, A. J., Carter, C. R., Madurska, M., Wilson, M. S. J., Fothergill, L., Skelly, B. L., Rutherford, C. L., Wilkinson, M. D., Malcolm, C., Baker, A. L., Tanner, N., Aleksandrov, D., Templeton, A., Shahin, Y., Luther, A.

Get full text

Cost‐effectiveness of emergency versus delayed laparoscopic cholecystectomy for acute gallbladder pathology by Sutton, A. J., Pasquali, S., Khan, R. B., Khan, M. A. S., Samuel, N., Jackson, A., Winter, H., Nijjar, R. S., Weerasinghe, C., Blazeby, J. M., Ho, W.‐M., Reed, J., Carney, K., Bunting, D.M., Wilson, T. R., Bartlett, F., Rae, D. M., Hornby, S. T., Eisawi, A., Abayomi, M., Mohamed, S., Hussain, A., Ebdewi, H., Gravante, G., Iqbal, L. G. N., Woodman, T., Malde, D., Satheesan, S., Boddy, A., Jones, R. P., Acharya, V., Jamdar, S., Sampat, K., Manu, M., Lewis, M., Roberts, G. P., Photi, E., Rodriguez, D., Rate, A. J., Henderson, L. T., Halkias, C., Al‐Muhktar, A., Bajwa, F. M., Choy, A., Pore, N., Taylor, C., Knight, B., Khan, S., Kansal, N., Fordham, I. J., Bausbacher, H., Akhtar, M., Raza, S., Haque, M., Booth, M. I., Wood, C. P. J., Gopalswamy, S., Awan, A., Goscimski, A., Kenny, R., Elkheir, N., Longbotham, D. A., Vijayanand, D., Hussain, A., Derbyshire, L., Appleton, S., Kanakala, V., Kaur, P., Barnes, J., Yao, C., Newton, R. C., Pannu, A., El‐Dhuwaib, Y., Thompson, R. L. E., McCune, K., Mawhinney, A., Jones, C., Clements, J.M., McKenzie, S., Spence, G., McEntee, G. P., Peirce, C., Thakkar, R., Martin, S. T., Nedujchelyn, Y., Ramage, M. I., Holroyd, D. J., Williamson, T. K., Carter, C. R., Lim, P. J., Boyce, K. M., Wilkinson, M. D., Malcolm, C., Radwan, R., Singh‐Ranger, D., Kanavati, O., Dhillon, A., McGuigan, A., Luther, A., Nicholson, J. A.

Get full text

Population-based cohort study of variation in the use of emergency cholecystectomy for benign gallbladder diseases by Vohra, R. S., Kennedy, D., Parappally, C. P., Zafar, S., Wheatley, K., Nijjar, R. S., Heath, J., Welbourn, H., Blazeby, J. M., Tang, C.‐B., Cowley, J. B., Hodgkins, K. A., Brennan, S., Jones, M. J., Jones, E., Kendal, C., Gough, M., Downing, J., Chauhan, N., Wild, J. R. L., Rao, S. T V., Siddiqi, N., Sen, G., Old, O. J., Shah, R., Weaver, S., Lammy, S., Giwa Nusrat Iqbal, L., Willson, P. D., Woodman, T., Lloyd, D., Jambulingam, P., Acharya, V., Larkin, D., Law, J., Chang, J., Rate, A. J., Robinson, S., Al‐Muhktar, A., Subramanium, D., Carter, N. C., Khan, S., Kansal, N., Gurung, K., Akhtar, M., Raza, S., Booth, M. I., Gopalswamy, S., Bullen, N., Psica, A., Li Goh, Y., Riera, M., Macano, C. A. W., Hoban, J. R., Williams, S. V., Hall, C., Elkheir, N., Hargreaves, A., Hussain, A., Henley, N., Ali, S., Dickson‐Lowe, R., Mirza, D., Al Amari, K., Patel, A., Preziosi, G., Segaran, A., Pezzuto, R., Hamilton, E., Farag, S. F., Simpson, D. J., Mawhinney, A., McCain, S., Cieplucha, K., Spence, G., Iskandar, E., McEntee, G. P., Cooke, F., Zeeshan, S., Holroyd, D. J., Jones, M. A., Weber, B., Carter, C. R., Knight, K., Boyd, A. T., Lim, P. J., Luhmann, A., Watson, A. J. M., Nicol, L., Ferguson, G., Lazim, T., Radwan, R., Baker, A. L., Tanner, N., O'Neill, S., Terrace, J., Hopwood, B., Aleksandrov, D., Weber, B., Nicholson, J. A.

Get full text

Correction: The Cholecystectomy As A Day Case (CAAD) Score: A Validated Score of Preoperative Predictors of Successful Day-Case Cholecystectomy Using the CholeS Data Set by El-Sharkawy, A. M., Tewari, N., Vohra, R. S.

Get full text

The Cholecystectomy As A Day Case (CAAD) Score: A Validated Score of Preoperative Predictors of Successful Day-Case Cholecystectomy Using the CholeS Data Set by El-Sharkawy, A. M., Tewari, N., Vohra, R. S.

Get full text

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones by Kusakabe, Manabu, Sun, Ann Chong, Tyshchenko, Kateryna, Wong, Rachel, Nanda, Aastha, Shanna, Claire, Gusscott, Samuel, Chavez, Elizabeth, Lorzadeh, Alireza, Zhu, Alice, Hill, Ainsleigh, Hung, Stacy, Brown, Scott, Babaian, Artem, Wang, Xuehai, Holt, Robert, Steidl, Christian, Karsan, Aly, Humphries, R. Keith, Eaves, Connie J., Hirst, Martin, Weng, Andrew P.

Get full text

Abstract B019: Clinical and molecular correlates of circulating tumor DNA (ctDNA) dynamics in breast tumors resistant to neoadjuvant therapy (NAT) by Magbanua, Mark Jesus M., Wolf, Denise M., Rivera-Hinojosa, Samuel, Ahmed, Ziad, Manon, Nayelis A., Sayaman, Rosalyn, Tin, Antony, Kalashnikova, Ekaterina, Swigart, Lamorna Brown, Hirst, Gillian L., Yau, Christina, Li, Wen, Isaacs, Claudine, Shatsky, Rebecca A., Delson, Amy L., Palsuledesai, Charuta C., Rodriguez, Angel, Liu, Minetta C., Pohlmann, Paula R., Esserman, Laura J., Rugo, Hope S., DeMichele, Angela, Veer, Laura van 't

Get full text

Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance by O’Connor, Michael D, Wederell, Elizabeth, Robertson, Gordon, Delaney, Allen, Morozova, Olena, Poon, Steven S.S, Yap, Damian, Fee, John, Zhao, Yongjun, McDonald, Helen, Zeng, Thomas, Hirst, Martin, Marra, Marco A, Aparicio, Samuel A.J.R, Eaves, Connie J

Get full text

Advanced Clinical Topics in Pediatric Palliative Care (P06) by Hwang, Jennifer Minarcik, MD MHS, Kang, Tammy, MD, Miller, Elissa, MD, Friebert, Sarah, MD FAAP FAAHPM, Santucci, Gina, MSN RN APRN-BC, Morrison, Wynne, MD, Klick, Jeffrey, MD, Goldstein, Richard, MD, Kobler, Kathie, MS APN PCNS-BC CHPPN, Ragsdale, Lindsay Burns, MD, Rossano, Joseph, MD MS FAAP FAAC, Kirsch, Roxanne, MD FRCPC FAAP, Goldfarb, Samuel B., MD, Dodds, Kathryn, MSN CRNP, Hirst, Jeremy, MD, Giamalis, John, PharmD, Berde, Charles, MD PhD

Get full text

Characterization Of The Effects Of Mutated EZH2 On Expression and Epigenome In a Mouse Lymphoma Model by Berg, Tobias, Thoene, Silvia, Yap, Damian, Wee, Tracee, Schoeler, Nathalie, Rosten, Patty, Lim, Emilia, Bilenky, Misha, Mungall, Andrew J, Oellerich, Thomas, Umlandt, Patricia, Salmi, Anisa, Chang, Harry, Yue, Lisa, Lai, David, Cheng, Grace, Serve, Hubert, Morin, Ryan D, Hirst, Martin, Marra, Marco A., Morin, Gregg B., Gascoyne, Randy D., Aparicio, Samuel A., Humphries, R. Keith

Get full text

Mutated EZH2 Collaborates with Myc in Inducing Lymphoma in a Mouse Model by Berg, Tobias, Yap, Damian, Thoene, Silvia, Wee, Tracee, Schoeler, Nathalie, Umlandt, Patricia, Chang, Harry, Yue, Lisa, Lai, David, Cheng, Grace, Morin, Ryan D, Hirst, Martin, Marra, Marco A., Morin, Gregg B., Gascoyne, Randy D., Aparicio, Samuel A., Humphries, R. Keith

Get full text