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Search Results - Holyer, Ian D.
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Resistance to anti-PD-1/anti-PD-L1: galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1
by
Mabbitt, Joseph
,
Holyer, Ian D.
,
Roper, James A.
,
Nilsson, Ulf J.
,
Zetterberg, Fredrik R.
,
Vuong, Lynda
,
Mackinnon, Alison C.
,
Pedersen, Anders
,
Slack, Robert J.
Published in
Frontiers in immunology
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Design, Synthesis, and Characterization of I‑BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate
by
Humphreys, Philip G
,
Atkinson, Stephen J
,
Bamborough, Paul
,
Bit, Rino A
,
Chung, Chun-wa
,
Craggs, Peter D
,
Cutler, Leanne
,
Davis, Rob
,
Ferrie, Alan
,
Gong, GangLi
,
Gordon, Laurie J
,
Gray, Matthew
,
Harrison, Lee A
,
Hayhow, Thomas G
,
Haynes, Andrea
,
Henley, Nick
,
Hirst, David J
,
Holyer, Ian D
,
Lindon, Matthew J
,
Lovatt, Cerys
,
Lugo, David
,
McCleary, Scott
,
Molnar, Judit
,
Osmani, Qendresa
,
Patten, Chris
,
Preston, Alex
,
Rioja, Inmaculada
,
Seal, Jonathan T
,
Smithers, Nicholas
,
Sun, Fenglai
,
Tang, Dalin
,
Taylor, Simon
,
Theodoulou, Natalie H
,
Thomas, Clare
,
Watson, Robert J
,
Wellaway, Christopher R
,
Zhu, Linrong
,
Tomkinson, Nicholas C. O
,
Prinjha, Rab K
Published in
Journal of medicinal chemistry
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Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I‑BET787
by
Hirst, David J.
,
Bamborough, Paul
,
Al-Mahdi, Niam
,
Angell, Davina C.
,
Barnett, Heather A.
,
Baxter, Andrew
,
Bit, Rino A.
,
Brown, Jack A.
,
Chung, Chun-wa
,
Craggs, Peter D.
,
Davis, Robert P.
,
Demont, Emmanuel H.
,
Ferrie, Alan
,
Gordon, Laurie J.
,
Harada, Isobel
,
Ho, Tim C. T.
,
Holyer, Ian D.
,
Hooper-Greenhill, Edward
,
Jones, Katherine L.
,
Lindon, Matthew J.
,
Lovatt, Cerys
,
Lugo, David
,
Maller, Claire
,
McGonagle, Grant
,
Messenger, Cassie
,
Mitchell, Darren J.
,
Pascoe, David D.
,
Patel, Vipulkumar K.
,
Patten, Christopher
,
Poole, Darren L.
,
Shah, Rishi R.
,
Rioja, Inmaculada
,
Stafford, Kayleigh A. J.
,
Tape, Daniel
,
Taylor, Simon
,
Theodoulou, Natalie H.
,
Tomlinson, Laura
,
Wall, Ian D.
,
Wellaway, Christopher R.
,
White, Gemma
,
Prinjha, Rab K.
,
Humphreys, Philip G.
Published in
Journal of medicinal chemistry
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BET bromodomain inhibitors show anti-papillomavirus activity in vitro and block CRPV wart growth in vivo
by
Morse, Mary A.
,
Balogh, Karla K.
,
Brendle, Sarah A.
,
Campbell, Colin A.
,
Chen, Mao X.
,
Furze, Rebecca C.
,
Harada, Isobel L.
,
Holyer, Ian D.
,
Kumar, Umesh
,
Lee, Kevin
,
Prinjha, Rab K.
,
Rüdiger, Martin
,
Seal, Jonathan T.
,
Taylor, Simon
,
Witherington, Jason
,
Christensen, Neil D.
Published in
Antiviral research
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Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells
by
Herman, Kimberly D
,
Holyer, Ian
,
Humphries, Duncan C
,
Adamska, Anna
,
Roper, James A
,
Peterson, Kristoffer
,
Zetterberg, Fredrik R
,
Pedersen, Anders
,
MacKinnon, Alison C
,
Slack, Robert J
Published in
International journal of molecular sciences
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