Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer by Hubbard, Gretchen K, Mutton, Laura N, Khalili, May, McMullin, Ryan P, Hicks, Jessica L, Bianchi-Frias, Daniella, Horn, Lucas A, Kulac, Ibrahim, Moubarek, Michael S, Nelson, Peter S, Yegnasubramanian, Srinivasan, De Marzo, Angelo M, Bieberich, Charles J

Get full text

MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer by Baena‐Del Valle, Javier A, Zheng, Qizhi, Esopi, David M, Rubenstein, Michael, Hubbard, Gretchen K, Moncaliano, Maria C, Hruszkewycz, Andrew, Vaghasia, Ajay, Yegnasubramanian, Srinivasan, Wheelan, Sarah J, Meeker, Alan K, Heaphy, Christopher M, Graham, Mindy K, De Marzo, Angelo M

Get full text

MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells by Iwata, Tsuyoshi, Schultz, Denise, Hicks, Jessica, Hubbard, Gretchen K, Mutton, Laura N, Lotan, Tamara L, Bethel, Carlise, Lotz, Matthew T, Yegnasubramanian, Srinivasan, Nelson, William G, Dang, Chi V, Xu, MengMeng, Anele, Uzoma, Koh, Cheryl M, Bieberich, Charles J, De Marzo, Angelo M

Get full text

PD-L1 Expression Varies in Thyroid Cancer Types and Is Associated with Decreased Progression Free Survival (PFS) in Patients with Anaplastic Thyroid Cancer by Shobab, Leila, Al-Souri, Deema, Mathews-Kim, Liza, McCoy, Matthew, Kuenstner, William, Hubbard, Gretchen K, Kumari, Sonam, Chou, Jiling, Lee, Wen, Rosen, Jennifer, Klubo-Gwiezdzinska, Joanna, Atkins, Michael, Wartofsky, Leonard, Vasko, Vasyl, Burman, Kenneth

Get full text

Characterization of novel cell lines derived from a MYC‐driven murine model of lethal metastatic adenocarcinoma of the prostate by Markowski, Mark C., Hubbard, Gretchen K., Hicks, Jessica L., Zheng, Qizhi, King, Alexia, Esopi, David, Rege, Apurv, Yegnasubramanian, Srinivasan, Bieberich, Charles J., De Marzo, Angelo M.

Get full text

Abstract 641: Use of conditional reprogramming to develop and characterize cell cultures from patient-derived xenograft (PDX) models of human lung and ovarian cancer by Borodovsky, Alexandra, McQuiston, Travis J., Dougherty, Brian, Ahmed, Ambar, Whitston, David, Stetson, Daniel, Hubbard, Gretchen K., Challberg, Sharon S., Pollok, Brian A., D’Cruz, Celina M.

Get full text

Abstract 5021: Histopathologic and gene expression analysis in mouse models of long-term chronic prostatic inflammation using human prostate cancer-derived bacterial isolates by Hubbard, Gretchen K., Yu, Shu-Han, Shinohara, Debika Biswal, Vaghasia, Ajay, Nelson, William G., Yegnasubramanian, Srinivasan, De Marzo, Angelo M., Sfanos, Karen S.

Get full text

Abstract 1086: MYC overexpression combined with Pten loss generates genomic instability and rapid metastasis in a new mouse model of lethal prostate adenocarcinoma by Hubbard, Gretchen K., Mutton, Laura N., Khalili, May, McMullin, Ryan P., Hicks, Jessica, Bianchi-Frias, Daniella, Nelson, Peter S., Yegnasubramanian, Srinivasan, De Marzo, Angelo M., Bieberich, Charles J.

Get full text

Abstract LB-160: Human telomerase RNA component (hTR/TERC) is consistently overexpressed in prostate cancer, required for cell proliferation and is positively regulated by MYC by Baena Del Valle, Javier A., Zheng, Qizhi, Rubenstein, Michael, Meeker, Alan K., Heaphy, Christopher M., Hubbard, Gretchen, Bieberich, Charles J., Yegnasubramanian, Srinivasan, Esopi, David, Wheelan, Sarah J., De Marzo, Angelo M.

Get full text