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Generation and Characterisation of KY1066, a Fully Human Antibody Targeting the Enzymatic Activity of Matriptase-2 for the Treatment of Iron Overload in Beta Thalassemia
by
Wake, Matthew
,
Papworth, Jonathan
,
Bayliss, Luke
,
Grimshaw, Benjamin
,
Rynkiewicz, Natalie
,
Paterson, Jemima
,
Poindron, Alicia
,
Spearing, Erin
,
Carter, Emily
,
Hudson, Robyne
,
Petzer, Verena
,
Largounez, Amelie
,
Belot, Audrey
,
Palin, Anais
,
Theurl, Igor
,
Germaschewski, Volker
,
Meynard, Delphine
Published in
Blood
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Abstract P074: MB097: A therapeutic consortium of bacteria clinically-defined by precision microbiome profiling of immune checkpoint inhibitor patients with potent anti-tumor effic...
by
Robinson, Matthew J.
,
Vervier, Kevin
,
Harris, Simon
,
Popple, Amy
,
Klisko, Dominika
,
Hudson, Robyne
,
Bakdash, Ghaith
,
Castan, Laure
,
Villemin, Clelia
,
Adams, David J.
,
Milne, Doreen
,
Booth, Catherine
,
Parkinson, Christine
,
Rabbie, Roy
,
Welsh, Sarah J.
,
Barker, Emily
,
Dalchau, Katie
,
Corrie, Pippa
,
Lawley, Trevor
Published in
Cancer immunology research
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A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice
by
Wake, Matthew
,
Palin, Anaïs
,
Belot, Audrey
,
Berger, Mathieu
,
Lorgouilloux, Megane
,
Bichon, Margot
,
Papworth, Jonathan
,
Bayliss, Luke
,
Grimshaw, Benjamin
,
Rynkiewicz, Natalie
,
Paterson, Jemima
,
Poindron, Alicia
,
Spearing, Erin
,
Carter, Emily
,
Hudson, Robyne
,
Campbell, Millie
,
Petzer, Verena
,
Besson-Fournier, Céline
,
Latour, Chloé
,
Largounez, Amélie
,
Gourbeyre, Ophélie
,
Fay, Alexis
,
Coppin, Hélène
,
Roth, Marie-Paule
,
Theurl, Igor
,
Germaschewski, Volker
,
Meynard, Delphine
Published in
Blood advances
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Blood
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Blood Advances
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Cancer Immunology Research
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Animals
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Beta-Thalassemia - Genetics
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Hematology
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Hepcidins
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Humans
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Iron - Metabolism
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Iron Overload - Drug Therapy
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Life Sciences
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Life Sciences & Biomedicine
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Membrane Proteins
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Mice
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Red Cells, Iron, And Erythropoiesis
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Science & Technology
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Serine Endopeptidases
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Splenomegaly
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