Process control of a dropwise additive manufacturing system for pharmaceuticals using polynomial chaos expansion based surrogate model by Içten, Elçin, Nagy, Zoltan K., Reklaitis, Gintaras V.

Get full text

Continuous Process Improvement in the Manufacture of Carfilzomib, Part 2: An Improved Process for Synthesis of the Epoxyketone Warhead by Beaver, Matthew G, Shi, Xianqing, Riedel, Jan, Patel, Parth, Zeng, Alicia, Corbett, Michael T, Robinson, Jo Anna, Parsons, Andrew T, Cui, Sheng, Baucom, Kyle, Lovette, Michael A, Içten, Elçin, Brown, Derek B, Allian, Ayman, Flick, Tawnya G, Chen, Wendy, Yang, Ning, Walker, Shawn D

Get full text

Knowledge Provenance Management System for a Dropwise Additive Manufacturing System for Pharmaceutical Products by Içten, Elçin, Joglekar, Girish, Wallace, Chelsey, Loehr, Kristen, Sacksteder, Jennifer, Giridhar, Arun, Nagy, Zoltan K, Reklaitis, Gintaras V

Get full text

Dropwise Additive Manufacturing of Pharmaceutical Products for Melt-Based Dosage Forms by Içten, Elçn, Giridhar, Arun, Taylor, Lynne S., Nagy, Zoltan K., Reklaitis, Gintaras V.

Get full text

Dropwise additive manufacturing of pharmaceutical products for amorphous and self emulsifying drug delivery systems by Içten, Elçin, Purohit, Hitesh S., Wallace, Chelsey, Giridhar, Arun, Taylor, Lynne S., Nagy, Zoltan K., Reklaitis, Gintaras V.

Get full text

A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 1: CDI-Promoted Amide Bond Formation by Içten, Elçin, Maloney, Andrew J., Beaver, Matthew G., Shen, Dongying Erin, Zhu, Xiaoxiang, Graham, Lauren R., Robinson, Jo Anna, Huggins, Seth, Allian, Ayman, Hart, Roger, Walker, Shawn D., Rolandi, Pablo, Braatz, Richard D.

Get full text

A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 3: Manganese-Catalyzed Asymmetric Epoxidation, Crystallization, and Filtr... by Maloney, Andrew J., Içten, Elçin, Capellades, Gerard, Beaver, Matthew G., Zhu, Xiaoxiang, Graham, Lauren R., Brown, Derek B., Griffin, Daniel J., Sangodkar, Rahul, Allian, Ayman, Huggins, Seth, Hart, Roger, Rolandi, Pablo, Walker, Shawn D., Braatz, Richard D.

Get full text

A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 2: Enone Synthesis via a Barbier-Type Grignard Process by Içten, Elçin, Maloney, Andrew J., Beaver, Matthew G., Zhu, Xiaoxiang, Shen, Dongying E., Robinson, Jo Anna, Parsons, Andrew T., Allian, Ayman, Huggins, Seth, Hart, Roger, Rolandi, Pablo, Walker, Shawn D., Braatz, Richard D.

Get full text

Green Chemistry as a Driver for Innovation in the Pharmaceutical Industry by Beaver, Matthew G., Caille, Seb, Içten, Elçin, Michalak, Sharon E., St‐Pierre, Gabrielle, Thiel, Oliver R.

Get full text

Drop-on-Demand System for Manufacturing of Melt-based Solid Oral Dosage: Effect of Critical Process Parameters on Product Quality by Içten, Elçin, Giridhar, Arun, Nagy, Zoltan K., Reklaitis, Gintaras V.

Get full text

Real-Time Process Management Strategy for Dropwise Additive Manufacturing of Pharmaceutical Products by Hirshfield, Laura, Içten, Elçin, Giridhar, Arun, Nagy, Zoltan K., Reklaitis, Gintaras V.

Get full text

Multi-omic characterization of antibody-producing CHO cell lines elucidates metabolic reprogramming and nutrient uptake bottlenecks by Gopalakrishnan, Saratram, Johnson, William, Valderrama-Gomez, Miguel A., Icten, Elcin, Tat, Jasmine, Lay, Fides, Diep, Jonathan, Gomez, Natalia, Stevens, Jennitte, Schlegel, Fabrice, Rolandi, Pablo, Kontoravdi, Cleo, Lewis, Nathan E.

Get full text

Guidelines for extracting biologically relevant context-specific metabolic models using gene expression data by Gopalakrishnan, Saratram, Joshi, Chintan J., Valderrama-Gómez, Miguel Á., Icten, Elcin, Rolandi, Pablo, Johnson, William, Kontoravdi, Cleo, Lewis, Nathan E.

Get full text

COSMIC-dFBA: A novel multi-scale hybrid framework for bioprocess modeling by Gopalakrishnan, Saratram, Johnson, William, Valderrama-Gomez, Miguel A., Icten, Elcin, Tat, Jasmine, Ingram, Michael, Fung Shek, Coral, Chan, Pik K., Schlegel, Fabrice, Rolandi, Pablo, Kontoravdi, Cleo, Lewis, Nathan E.

Get full text