Search Results - Iikubo, Kazuhiko

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  1. 1
    Discovery of ASP5878: Synthesis and structure–activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel inhibitory activity

    Discovery of ASP5878: Synthesis and structure–activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel... by Kuriwaki, Ikumi, Kameda, Minoru, Iikubo, Kazuhiko, Hisamichi, Hiroyuki, Kawamoto, Yuichiro, Kikuchi, Shigetoshi, Moritomo, Hiroyuki, Terasaka, Tadashi, Iwai, Yoshinori, Noda, Atsushi, Tomiyama, Hiroshi, Kikuchi, Aya, Hirano, Masaaki

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  2. 2
    Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2

    Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2 by Kuriwaki, Ikumi, Kameda, Minoru, Hisamichi, Hiroyuki, Kikuchi, Shigetoshi, Iikubo, Kazuhiko, Kawamoto, Yuichiro, Moritomo, Hiroyuki, Kondoh, Yutaka, Amano, Yasushi, Tateishi, Yukihiro, Echizen, Yuka, Iwai, Yoshinori, Noda, Atsushi, Tomiyama, Hiroshi, Suzuki, Tomoyuki, Hirano, Masaaki

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  3. 3
    Synthesis and structure–activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)–anaplastic lymphoma kinase (ALK) inhibitors

    Synthesis and structure–activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)–anaplastic lymphoma kinase (AL... by Iikubo, Kazuhiko, Kurosawa, Kazuo, Matsuya, Takahiro, Kondoh, Yutaka, Kamikawa, Akio, Moritomo, Ayako, Iwai, Yoshinori, Tomiyama, Hiroshi, Shimada, Itsuro

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  4. 4
    Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency

    Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro po... by Kuriwaki, Ikumi, Kameda, Minoru, Iikubo, Kazuhiko, Hisamichi, Hiroyuki, Kawamoto, Yuichiro, Kikuchi, Shigetoshi, Moritomo, Hiroyuki, Kondoh, Yutaka, Terasaka, Tadashi, Amano, Yasushi, Tateishi, Yukihiro, Echizen, Yuka, Iwai, Yoshinori, Noda, Atsushi, Tomiyama, Hiroshi, Nakazawa, Taisuke, Hirano, Masaaki

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  5. 5
    Synthesis and structure–activity relationship of fused-pyrimidine derivatives as a series of novel GPR119 agonists

    Synthesis and structure–activity relationship of fused-pyrimidine derivatives as a series of novel GPR119 agonists by Negoro, Kenji, Yonetoku, Yasuhiro, Moritomo, Ayako, Hayakawa, Masahiko, Iikubo, Kazuhiko, Yoshida, Shigeru, Takeuchi, Makoto, Ohta, Mitsuaki

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  6. 6
    The first direct synthesis of α-mangostin, a potent inhibitor of the acidic sphingomyelinase

    The first direct synthesis of α-mangostin, a potent inhibitor of the acidic sphingomyelinase by Iikubo, Kazuhiko, Ishikawa, Yuichi, Ando, Noritaka, Umezawa, Kazuo, Nishiyama, Shigeru

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  7. 7
    Biological activities of α-mangostin derivatives against acidic sphingomyelinase

    Biological activities of α-mangostin derivatives against acidic sphingomyelinase by Hamada, Motoko, Iikubo, Kazuhiko, Ishikawa, Yuichi, Ikeda, Aya, Umezawa, Kazuo, Nishiyama, Shigeru

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