Optimization of an azetidine series as inhibitors of colony stimulating factor-1 receptor (CSF-1R) Type II to lead to the clinical candidate JTE-952 by Ikegashira, Kazutaka, Ikenogami, Taku, Yamasaki, Takayuki, Oka, Takahiro, Hase, Yasunori, Miyagawa, Naoki, Inagaki, Koji, Kawahara, Iichiro, Koga, Yoshihisa, Hashimoto, Hiromasa

Get full text

Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models by Ikegashira, Kazutaka, Ikenogami, Taku, Yamasaki, Takayuki, Hase, Yasunori, Yamaguchi, Takayuki, Inagaki, Koji, Doi, Satoki, Adachi, Tsuyoshi, Koga, Yoshihisa, Hashimoto, Hiromasa

Get full text

Discovery of Second Generation RORγ Inhibitors Composed of an Azole Scaffold by Kotoku, Masayuki, Maeba, Takaki, Fujioka, Shingo, Yokota, Masahiro, Seki, Noriyoshi, Ito, Keisuke, Suwa, Yoshihiro, Ikenogami, Taku, Hirata, Kazuyuki, Hase, Yasunori, Katsuda, Yoshiaki, Miyagawa, Naoki, Arita, Kojo, Asahina, Kota, Noguchi, Masato, Nomura, Akihiro, Doi, Satoki, Adachi, Tsuyoshi, Crowe, Paul, Tao, Haiyan, Thacher, Scott, Hashimoto, Hiromasa, Suzuki, Takayoshi, Shiozaki, Makoto

Get full text

Discovery of a Potent and Short−Acting Oral Calcilytic with a Pulsatile Secretion of Parathyroid Hormone by Shinagawa, Yuko, Inoue, Teruhiko, Katsushima, Takeo, Kiguchi, Toshihiro, Ikenogami, Taku, Ogawa, Naoki, Fukuda, Kenji, Hirata, Kazuyuki, Harada, Kazuhito, Takagi, Masaki, Nakagawa, Takashi, Kimura, Shuichi, Matsuo, Yushi, Maekawa, Mariko, Hayashi, Mikio, Soejima, Yuki, Takahashi, Mitsuru, Shindo, Masanori, Hashimoto, Hiromasa

Get full text

Stereoselective synthesis of C-4′-aminouridines (uracil C-4-amino-D-ribonucleosides) by Yokoyama, Masataka, Ikenogami, Taku, Togo, Hideo

Get full text