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Asciminib, a novel allosteric inhibitor of BCR‐ABL1, shows synergistic effects when used in combination with imatinib with or without drug resistance
by
Okamoto, Naoki
,
Yagi, Kenta
,
Imawaka, Sayaka
,
Takaoka, Mayu
,
Aizawa, Fuka
,
Niimura, Takahiro
,
Goda, Mitsuhiro
,
Miyata, Koji
,
Kawada, Kei
,
Izawa‐Ishizawa, Yuki
,
Sakaguchi, Satoshi
,
Ishizawa, Keisuke
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Pharmacology research & perspectives
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Pharmacology Research & Perspectives
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Antineoplastic Agents - Pharmacology
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Antineoplastic Combined Chemotherapy Protocols - Pharmacology
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Apoptosis
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Asciminib
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Bcr‐Abl Inhibitors
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Binding Sites
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Cell Cycle
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Cell Growth
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Cell Survival - Drug Effects
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Chronic Myelogenous Leukemia
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Drug Dosages
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Drug Resistance
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Drug Resistance, Neoplasm - Drug Effects
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Drug Resistance, Neoplasm - Genetics
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Drug Synergism
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Fusion Proteins, Bcr-Abl - Antagonists & Inhibitors
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Fusion Proteins, Bcr-Abl - Genetics
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Gene Expression
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Humans
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Imatinib Mesylate - Pharmacology
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