Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study by Knight, Stephen R, Holden, Karl A, Merson, Laura, Russell, Clark D, Solomon, Tom, Carson, Gail, Olliaro, Piero, Semple, Malcolm G, Alex, Beatrice, Bach, Benjamin, Dunning, Jake, da Silva Filipe, Ana, Horby, Peter W, Law, Andrew, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Scott, Janet T, de Silva, Thushan, Sigfrid, Louise, Tedder, Richard S, Thwaites, Ryan S, Turtle, Lance CW, Andrikopoulos, Petros, Liggi, Sonia, Sands, Caroline, Fairfield, Cameron J, Shaw, Catherine A, Dalton, Jo, Girvan, Michelle, Hendry, Ross, Greenhalf, William, McDonald, Sarah E, Booth, Laura, Catterall, Benjamin WA, Clarke, Emily A, Dincarslan, Oslem, Dyer, Philip, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L, Jones, Christopher B, Khandaker, Shadia, Lefteri, Daniella, Livoti, Lucia A, Middleton, Joanna, Reynolds, Will, Ridley, P. Matthew, Shaw, Victoria E, Tanianis-Hughes, Jolanta, Trochu, Erwan, Flaherty, Lisa, Massey, Hannah, Aldera, Erin L., Alegria, Ana, Barnass, Stella, Barrett, Nicholas, Basude, Sneha, Baxter, David, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Douthwaite, Sam, Fullerton, Duncan, Garg, Atul, Hawcutt, Daniel B, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Koduri, Gouri, Laird, Steven, Leiner, Tamas, Little, Jeff, McEwen, Ruth, Morris, Craig, Moses, Samuel, Norris, Lillian, Panchatsharam, Selva, Pattison, Natalie, Peters, Mark, Price, David, Prout, Rachel, Richardson, Neil, Rousseau, Guy, Ryan, Brendan, Sharma, Anil, Stambach, Tom, Stewart, Richard, Thompson, Robert, Tridente, Ascanio, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Wilson, Lawrence, Wiselka, Martin, Wootton, Daniel G, Workman, Andrew, Young, Peter

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Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19 by Siggins, Matthew K., Davies, Kate, Fellows, Rosie, Thwaites, Ryan S., Baillie, J. Kenneth, Semple, Malcolm G., Openshaw, Peter J. M., Zelek, Wioleta M., Harris, Claire L., Morgan, B. Paul

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Fewer COVID‐19 Neurological Complications with Dexamethasone and Remdesivir by Grundmann, Alexander, Wu, Chieh‐Hsi, Hardwick, Marc, Baillie, J. Kenneth, Openshaw, Peter J M, Semple, Malcolm G., Böhning, Dankmar, Pett, Sarah, Michael, Benedict D., Thomas, Rhys H., Galea, Ian

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Genetic mechanisms of critical illness in COVID-19 by Pairo-Castineira, Erola, Clohisey, Sara, Klaric, Lucija, Bretherick, Andrew D., Rawlik, Konrad, Pasko, Dorota, Walker, Susan, Parkinson, Nick, Fourman, Max Head, Russell, Clark D., Furniss, James, Richmond, Anne, Gountouna, Elvina, Wrobel, Nicola, Harrison, David, Wang, Bo, Wu, Yang, Meynert, Alison, Griffiths, Fiona, Oosthuyzen, Wilna, Kousathanas, Athanasios, Moutsianas, Loukas, Yang, Zhijian, Zhai, Ranran, Zheng, Chenqing, Grimes, Graeme, Beale, Rupert, Millar, Jonathan, Shih, Barbara, Keating, Sean, Zechner, Marie, Haley, Chris, Porteous, David J., Hayward, Caroline, Yang, Jian, Knight, Julian, Summers, Charlotte, Shankar-Hari, Manu, Klenerman, Paul, Turtle, Lance, Ho, Antonia, Moore, Shona C., Hinds, Charles, Horby, Peter, Nichol, Alistair, Maslove, David, Ling, Lowell, McAuley, Danny, Montgomery, Hugh, Walsh, Timothy, Pereira, Alexandre C., Renieri, Alessandra, Shen, Xia, Ponting, Chris P., Fawkes, Angie, Tenesa, Albert, Caulfield, Mark, Scott, Richard, Rowan, Kathy, Murphy, Lee, Openshaw, Peter J. M., Semple, Malcolm G., Law, Andrew, Vitart, Veronique, Wilson, James F., Baillie, J. Kenneth

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Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients by Ijaz, Samreen, Dicks, Steve, Jegatheesan, Keerthana, Parker, Eleanor, Katsanovskaja, Ksenia, Vink, Elen, McClure, Myra O., Shute, J., Hope, Joshua, Cook, Nicola, Cherepanov, Peter, Turtle, Lance, Paxton, William A., Pollakis, Georgios, Ho, Antonia, Openshaw, Peter J.M., Baillie, J. Kenneth, Semple, Malcolm G., Tedder, Richard S.

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Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19 by Thwaites, Ryan S, Sanchez Sevilla Uruchurtu, Ashley, Siggins, Matthew K, Liew, Felicity, Russell, Clark D, Moore, Shona C, Fairfield, Cameron, Carter, Edwin, Abrams, Simon, Short, Charlotte-Eve, Thaventhiran, Thilipan, Bergstrom, Emma, Gardener, Zoe, Ascough, Stephanie, Chiu, Christopher, Docherty, Annemarie B, Hunt, David, Crow, Yanick J, Solomon, Tom, Taylor, Graham P, Turtle, Lance, Harrison, Ewen M, Dunning, Jake, Semple, Malcolm G, Baillie, J Kenneth, Openshaw, Peter Jm

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Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves by Swann, Olivia V., Pollock, Louisa, Holden, Karl A., Munro, Alasdair P. S., Bennett, Aisleen, Williams, Thomas C., Turtle, Lance, Fairfield, Cameron J., Drake, Thomas M., Faust, Saul N., Sinha, Ian P., Roland, Damian, Whittaker, Elizabeth, Ladhani, Shamez N., Nguyen-Van-Tam, Jonathan S., Girvan, Michelle, Donohue, Chloe, Donegan, Cara, Spencer, Rebecca G., Hardwick, Hayley E., Openshaw, Peter J. M., Baillie, J. Kenneth, Harrison, Ewen M., Docherty, Annemarie B., Semple, Malcolm G.

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Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study by Docherty, Annemarie B, Harrison, Ewen M, Green, Christopher A, Hardwick, Hayley E, Pius, Riinu, Norman, Lisa, Holden, Karl A, Read, Jonathan M, Dondelinger, Frank, Carson, Gail, Merson, Laura, Lee, James, Plotkin, Daniel, Sigfrid, Louise, Halpin, Sophie, Jackson, Clare, Gamble, Carrol, Horby, Peter W, Nguyen-Van-Tam, Jonathan S, Ho, Antonia, Russell, Clark D, Dunning, Jake, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G

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Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score by Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M

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Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study by Halpin, Sophie, Donohue, Chloe, Ladhani, Shamez, Horby, Peter W, Docherty, Annemarie B, Semple, Malcolm G, Openshaw, Peter J M, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Horby, Peter W, Klenerman, Paul, Law, Andrew, Moore, Shona C, Palmarini, Massimo, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Thomson, Emma C, Oosthuyzen, Wilna, Norman, Lisa, Pius, Riinu, Mclean, Kenneth A, Saviciute, Egle, Leeming, Gary, Hendry, Ross, Greenhalf, William, Ahmed, Katie A, Asiimwe, Innocent G, Brennan, Benjamin, Catterall, Benjamin WA, Clark, Jordan J, Cole, Sarah, Cox, Helen, Elliott, Angela, Foster, Terry, Greenhalf, Willliam, Jones, Trevor R, Murphy, Ellen G, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis, Jolanta, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Agranoff, Daniel, Angus, Brian, Atkinson, Dougal, Barlow, Gavin, Barrett, Nicholas, Bassford, Christopher, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cupitt, Jason, Dark, Paul, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Fegan, Christopher, Finn, Adam, Fullerton, Duncan, Goldsmith, Arthur, Hardy, Elaine, Havalda, Peter, Holme, Anita, Kendall, Jason, Kerrison, Caroline, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, MacNaughton, Emily, McCullough, Katherine, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Nelson, Mark, Panchatsharam, Selva, Pintus, Stefania, Prout, Rachel, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shanmuga, Prad, Sharma, Anil, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Stambach, Tom, Tridente, Ascanio, Ustianowski, Andrew, Waddy, Sam, Whittaker, Paul, Williams, Martin, Wiselka, Martin, Young, Peter

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SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses by Swets, Maaike C, Russell, Clark D, Harrison, Ewen M, Docherty, Annemarie B, Lone, Nazir, Girvan, Michelle, Hardwick, Hayley E, Visser, Leonardus G, Openshaw, Peter J M, Groeneveld, Geert H, Semple, Malcolm G, Baillie, J Kenneth

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Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity by Thomson, Emma C., Rosen, Laura E., Shepherd, James G., Spreafico, Roberto, da Silva Filipe, Ana, Wojcechowskyj, Jason A., Davis, Chris, Piccoli, Luca, Pascall, David J., Dillen, Josh, Lytras, Spyros, Czudnochowski, Nadine, Shah, Rajiv, Meury, Marcel, Jesudason, Natasha, De Marco, Anna, Li, Kathy, Bassi, Jessica, O’Toole, Aine, Pinto, Dora, Colquhoun, Rachel M., Culap, Katja, Jackson, Ben, Zatta, Fabrizia, Rambaut, Andrew, Jaconi, Stefano, Sreenu, Vattipally B., Nix, Jay, Zhang, Ivy, Jarrett, Ruth F., Glass, William G., Beltramello, Martina, Nomikou, Kyriaki, Pizzuto, Matteo, Tong, Lily, Cameroni, Elisabetta, Croll, Tristan I., Johnson, Natasha, Di Iulio, Julia, Wickenhagen, Arthur, Ceschi, Alessandro, Harbison, Aoife M., Mair, Daniel, Ferrari, Paolo, Smollett, Katherine, Sallusto, Federica, Carmichael, Stephen, Garzoni, Christian, Nichols, Jenna, Galli, Massimo, Hughes, Joseph, Riva, Agostino, Ho, Antonia, Schiuma, Marco, Semple, Malcolm G., Openshaw, Peter J.M., Fadda, Elisa, Baillie, J. Kenneth, Chodera, John D., Rihn, Suzannah J., Lycett, Samantha J., Virgin, Herbert W., Telenti, Amalio, Corti, Davide, Robertson, David L., Snell, Gyorgy

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A prenylated dsRNA sensor protects against severe COVID-19 by Wickenhagen, Arthur, Sugrue, Elena, Lytras, Spyros, Kuchi, Srikeerthana, Noerenberg, Marko, Turnbull, Matthew L, Loney, Colin, Herder, Vanessa, Allan, Jay, Jarmson, Innes, Cameron-Ruiz, Natalia, Varjak, Margus, Pinto, Rute M, Lee, Jeffrey Y, Iselin, Louisa, Palmalux, Natasha, Stewart, Douglas G, Swingler, Simon, Greenwood, Edward J D, Crozier, Thomas W M, Gu, Quan, Davies, Emma L, Clohisey, Sara, Wang, Bo, Trindade Maranhão Costa, Fabio, Freire Santana, Monique, de Lima Ferreira, Luiz Carlos, Murphy, Lee, Fawkes, Angie, Meynert, Alison, Grimes, Graeme, Da Silva Filho, Joao Luiz, Marti, Matthias, Hughes, Joseph, Stanton, Richard J, Wang, Eddie C Y, Ho, Antonia, Davis, Ilan, Jarrett, Ruth F, Castello, Alfredo, Robertson, David L, Semple, Malcolm G, Openshaw, Peter J M, Palmarini, Massimo, Lehner, Paul J, Baillie, J Kenneth, Rihn, Suzannah J, Wilson, Sam J

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Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study by Drake, Thomas M, Docherty, Annemarie B, Harrison, Ewen M, Quint, Jennifer K, Adamali, Huzaifa, Agnew, Sarah, Babu, Suresh, Barber, Christopher M, Barratt, Shaney, Bendstrup, Elisabeth, Bianchi, Stephen, Villegas, Diego Castillo, Chaudhuri, Nazia, Chua, Felix, Coker, Robina, Chang, William, Crawshaw, Anjali, Crowley, Louise E, Dosanjh, Davinder, Fiddler, Christine A, Forrest, Ian A, George, Peter M, Gibbons, Michael A, Groom, Katherine, Haney, Sarah, Hart, Simon P, Heiden, Emily, Henry, Michael, Ho, Ling-Pei, Hoyles, Rachel K, Hutchinson, John, Hurley, Killian, Jones, Mark, Jones, Steve, Kokosi, Maria, Kreuter, Michael, MacKay, Laura S, Mahendran, Siva, Margaritopoulos, George, Molina-Molina, Maria, Molyneaux, Philip L, O'Brien, Aiden, O'Reilly, Katherine, Packham, Alice, Parfrey, Helen, Poletti, Venerino, Porter, Joanna C, Renzoni, Elisabetta, Rivera-Ortega, Pilar, Russell, Anne-Marie, Saini, Gauri, Spencer, Lisa G, Stella, Giulia M, Stone, Helen, Sturney, Sharon, Thickett, David, Thillai, Muhunthan, Wallis, Tim, Ward, Katie, Wells, Athol U, West, Alex, Wickremasinghe, Melissa, Woodhead, Felix, Hearson, Glenn, Howard, Lucy, Baillie, J Kenneth, Openshaw, Peter J M, Semple, Malcolm G, Stewart, Iain, Jenkins, R Gisli

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Hospital-acquired SARS-CoV-2 infection in the UK's first COVID-19 pandemic wave by Read, Jonathan M, Green, Chris A, Harrison, Ewen M, Docherty, Annemarie B, Funk, Sebastian, Harrison, Janet, Girvan, Michelle, Hardwick, Hayley E, Turtle, Lance, Dunning, Jake, Nguyen-Van-Tam, Jonathan S, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G

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Estimating distribution of length of stay in a multi-state model conditional on the pathway, with an application to patients hospitalised with Covid-19 by Keogh, Ruth H., Diaz-Ordaz, Karla, Jewell, Nicholas P., Semple, Malcolm G., de Wreede, Liesbeth C., Putter, Hein

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Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, pr... by Fairfield, Cameron J, Drake, Thomas M, Sigfrid, Louise, Docherty, Annemarie B, Girvan, Michelle, Dunning, Jake, Openshaw, Peter J M, Openshaw, Peter JM, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Law, Andrew, Merson, Laura, Moore, Shona C, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Tedder, Richard S, Palmieri, Carlo, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Shaw, Victoria, McDonald, Sarah E, Keating, Seán, Armstrong, Jane A, Ashworth, Milton, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Garcia-Dorival, Isabel, Jones, Christopher B, Khandaker, Shadia, Lant, Suzannah, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McLauchlan, John, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis-Hughes, Jolanta, van Tonder, Libby, Wilcock, Eve, Flaherty, Lisa, MacLean, Alan, Agranoff, Daniel, Aldera, Erin L., Alegria, Ana, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Basude, Sneha, Chadwick, David, Chee, Nigel, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Dark, Paul, Donnison, Phil, Douthwaite, Sam, Dushianthan, Ahilanadan, Eziefula, Chi, Fegan, Chrisopher, Garg, Atul, Hawcutt, Daniel B, Hobrok, Maria, Jennings, Paul, Koduri, Gouri, Laha, Shondipon, Laird, Steven, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, McCullough, Katherine, Mirfenderesky, Mariyam, Mohandas, Kavya, Morris, Craig, Nagel, Megan, Papakonstantino, Danai, Pintus, Stefania, Singh Pooni, Jagtur, Prout, Rachel, Roberts, Devender, Rose, Alistair, Shawcross, Anna, Tatham, Kate, Vuylsteke, Alan, Whittaker, Paul, Wiselka, Martin

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Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID‐19 by Devine, Kerri, Russell, Clark D., Blanco, Giovanny R., Walker, Brian R., Homer, Natalie Z. M., Denham, Scott G., Simpson, Joanna P., Leavy, Olivia C., Elneima, Omer, McAuley, Hamish J. C., Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Saunders, Ruth M., Harris, Victoria C., Houchen‐Wolloff, Linzy, Greening, Neil J., Lone, Nazir I., Thorpe, Mathew, Greenhalf, William, Chalmers, James D., Ho, Ling‐Pei, Horsley, Alex, Marks, Michael, Raman, Betty, Moore, Shona C., Dunning, Jake, Semple, Malcolm G., Andrew, Ruth, Wain, Louise V., Evans, Rachael A., Brightling, Christopher E., Kenneth Baillie, John, Reynolds, Rebecca M.

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Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study by Turtle, Lance, Thorpe, Mathew, Drake, Thomas M, Swets, Maaike, Palmieri, Carlo, Russell, Clark D, Ho, Antonia, Aston, Stephen, Wootton, Daniel G, Richter, Alex, de Silva, Thushan I, Hardwick, Hayley E, Leeming, Gary, Law, Andy, Openshaw, Peter J M, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B

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Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study by Sullivan, Michael K, Lees, Jennifer S, Drake, Thomas M, Docherty, Annemarie B, Oates, Georgia, Hardwick, Hayley E, Russell, Clark D, Merson, Laura, Dunning, Jake, Nguyen-Van-Tam, Jonathan S, Openshaw, Peter, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Ho, Antonia, Mark, Patrick B

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